Valerian

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Valerian is a non-scientific common name that may refer to a number of plant species and varieties.

Nomenclature

Other Names:

Historical Use of Valerian

Valerian in Traditional Chinese Medicine

Description

Historical Use of Valerian in Western Medicine

Quote Paraph: "The greater part, however, of those taken from the vegetable kingdom, are manifestly inert and insignificant. Even the root of the wild valerian hardly supports its credit."
Sec Auth: Eadie MJ and Bladin PF
Title: A Disease Once Sacred. John Libbey & Company Ltd, 2001
Page: 192
Source: A Disease Once Sacred, John Libbey & Company Ltd, 2001, M.J. Eadie and P.F. Bladin
Complete: Eadie MJ, Bladin PF. A disease once sacred: a history of the medical understanding of epilepsy. Eastleigh: John Libbey; 2001. p. 192.
Primary Source: First Lines of the Practice of Physic by William Cullen

Background

Synonymns for Valerian

Patent Medicines and Medicines with Multiple Ingredients that include Valerian

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Valerian in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

A Kapucu, S Ustunova, K Akgun-Dar
Valeriana officinalis extract and 7-Nitroindozole ameliorated seizure behaviours, and 7-Nitroindozole reduced blood pressure and ECG parameters in pentylenetetrazole-kindled rats.
Pol J Vet Sci: 2020, 23(3);349-357
[PubMed:33006866] [WorldCat.org] [DOI] (I p)

María Eva González-Trujano, Gerardo Contreras-Murillo, Claudia Andrea López-Najera, Fernando Josué Hidalgo-Flores, Andrés Navarrete-Castro, Concepción Gamboa Sánchez, Víctor Manuel Magdaleno-Madrigal
Anticonvulsant activity of Valeriana edulis roots and valepotriates on the pentylenetetrazole-induced seizures in rats.
J Ethnopharmacol: 2021, 265;113299
[PubMed:32841694] [WorldCat.org] [DOI] (I p)

Hwayoung Lee, Jiyun Im, Hansol Won, Jun Young Kim, Hyung-Ki Kim, Jun-Tack Kwon, Young Ock Kim, Sanghyun Lee, Ik-Hyun Cho, Sang Won Lee, Hak-Jae Kim
Antinociceptive effect of Valeriana fauriei regulates BDNF signaling in an animal model of fibromyalgia.
Int J Mol Med: 2018, 41(1);485-492
[PubMed:29115388] [WorldCat.org] [DOI] (I p)

Fahimeh Moradi-Afrapoli, Samad Nejad Ebrahimi, Martin Smiesko, Matthias Hamburger
##Title##
J Nat Prod: 2017, 80(5);1548-1557
[PubMed:28485933] [WorldCat.org] [DOI] (I p)

Kiyohisa Yanagisawa
Transition of Psychotropic Drugs in Japanese Pharmacopoeia (JP) (Part 17) Transitions in the Standards and Test Methods of Valproic Acid and Sodium Valproate in Japanese Pharmacopoeia (JP), Pharmacopoeia of the USA (USP), British Pharmacopoeia (BP), and the Knowledge and Judgment about Japanese Valeriana, and Valproic Acid from Valeric Acid
Yakushigaku Zasshi: 2018, 51(1);40-57
[PubMed:30183146] [WorldCat.org] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects