Rhaponticum uniflorum
Contents
Nomenclature
Other Names:
Historical Use of Rhaponticum uniflorum
Rhaponticum uniflorum in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Loulu
Chinese Name :
Common Name :Uniflower Swisscentaury
Specific Name : Radix rhapontici
Scientific Name:
Collection : The drug is collected in spring and autumn, removed from rootlet and soil and dried in the sun.
Description : Conical or flatted lumps, mostly twisted, varying in length, 1-2 cm in diameter. Externally greyish brown or dark brown, rough with longitudinal furrows and rhombic, netted clefts. Outer bark easily exfoliated. Root stock swollen with the remains of the stem and scaly leaf bases, top with greyish white pubescents. Texture light, fragile, easily broken, fracture irregular, greyish yellow, cleft, greyish black or brownish black in the center. Odour characteristic, taste slightly bitter.
Identification : To 1 g of the powder add 20 ml of methanol, ultra-sonicate for 20 minutes, filter, evaporate the filtrate on a water bath to dryness. Dissolve the residue in 1 ml of ethyl acetate and use it as the test solution. Prepare a solution of Radix Rhpontici reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G as the coating substance and cyclohexane butanone (4:1) as the mobile phase. Apply separately 5 µl of each of the two solutions to the plate. After developing and removal of the plate, dry it in the air. Examine under ultra violet light (365 nm). A spot in the chromatogram obtained from the test solution correspond in color to the spot in the chromatogram obtained from the reference drug solution.
Processing : Eliminate foreign matter, wash, clean soften thoroughly, cut into thick slices and dry in the sun.
Action : To remove toxic heat for treating subcutaneous infections, to promote lactation, and to relieve muscular contracture.
Indication : mastitis with swelling and pain, carbuncle, scrofula and ulcers; galactostasis; arthritis with ankylosis
Precautions : Used with caution in pregnancy.
Dosage : 5 to 9 g.
Storage : Preserve in a ventilated and dry place.
Synonymns for Rhaponticum uniflorum
Patent Medicines and Medicines with Multiple Ingredients that include Rhaponticum uniflorum
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Rhaponticum uniflorum in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Anyuta A Toropova, Yanina G Razuvaeva, Daniil N Olennikov, Kristina V Markova, Sergey V Lemza
##Title##
Nat Prod Res: 2023, 37(22);3878-3883
[PubMed:36495287]
[WorldCat.org]
[DOI]
(I p)
Daniil N Olennikov
##Title##
Biomolecules: 2022, 12(11);
[PubMed:36421734]
[WorldCat.org]
[DOI]
(I e)
Dong Zhen, Chunyan Liu, Tianpeng Huang, Danni Fu, Xue Bai, Qianqian Ma, Mingyang Jiang, Guohua Gong
Ethanol extracts of Rhaponticum uniflorum (L.) DC inflorescence ameliorate LPS-mediated acute lung injury by alleviating inflammatory responses via the Nrf2/HO-1 signaling pathway.
J Ethnopharmacol: 2022, 296;115497
[PubMed:35738472]
[WorldCat.org]
[DOI]
(I p)
Hu Boqin, Qiang Zhou, Liqiang Wang, Mei Jiang, Guohua Gong, Chang Liu, Chengxi Wei
##Title##
Mitochondrial DNA B Resour: 2022, 7(1);303-305
[PubMed:35128058]
[WorldCat.org]
[DOI]
(I e)
Boqin Hu, Dong Zhen, Meirong Bai, Tianqi Xuan, Yu Wang, Mingjie Liu, Lijun Yu, Dongsong Bai, Danni Fu, Chengxi Wei
Ethanol extracts of Rhaponticum uniflorum (L.) DC flowers attenuate doxorubicin-induced cardiotoxicity via alleviating apoptosis and regulating mitochondrial dynamics in H9c2 cells.
J Ethnopharmacol: 2022, 288;114936
[PubMed:35007682]
[WorldCat.org]
[DOI]
(I p)
