Difference between revisions of "Pseudolarix kaempferi"

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Latest revision as of 14:33, 21 March 2013

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Nomenclature

Other Names:

Historical Use of Pseudolarix kaempferi

Pseudolarix kaempferi in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Tujingpi

Chinese Name  :

Common Name  :Golden Larch Bark

Specific Name  : Cortex pseudolaricis

Scientific Name:
Collection  : The drug is collected in summer and dried in the sun.

Description  : Root bark irregularly long slat-shape, twisted and slightly rolled, variable in size, 2-5mm thick. Outer surface greyish yellow, rough wrinkled and greyish white transversely lenticelllate and the rugged external tissues frequently scaling off with reddish brown expose surface. Inner surface yellowish brown to reddish-brown, even with fine longitudinal striations. Texture flexible, fracture splintery, easily detachable in flakes. Odour slight, taste bitter and astringent, stem bark in flattish pieces up to about 8mm thick, the rugged external tissues relativerly thick, the outer surface cracked and the inner surface relatively rough.

Identification  : Powder: Pale brown or brownish-red, stone cells abundant, subrectangular, subrounded or irregular branched 30-96µm in diameter containing yellowish brown masses. Most sieve cells in bundles, 20-40µm in diameter, numerous elliptical sieve areas scattered over the side walls, mucilage cells subrounded, 100-300µm in diameter. Resin cells longitudinally connected into tube form containing reddish brown to yellowish brown resinous matter. Sometimes with prisms of calcium oxalate embedded in them. Walls of cork cells slightly thick, some of them lignified and pitted.

Processing  : Wash clean, soften slightly, cut into slivers and dry in the sun.

Action  : To kill parasites and relieve itching.

Indication  : scabies, tinea

Precautions  :

Dosage  : Appropriate quantity soaked with vinegar or wine, or ground into powder and mixed with water to be apllied topically.

Storage  : Preserve in a dry place.

Synonymns for Pseudolarix kaempferi

Patent Medicines and Medicines with Multiple Ingredients that include Pseudolarix kaempferi

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Pseudolarix kaempferi in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Dan Luo, Fang He, Jingyun Liu, Xueting Dong, Mengying Fang, Yuling Liang, Mengqin Chen, Xuemei Gui, Wenjun Wang, Li Zeng, Xianming Fan, Qibiao Wu
Pseudolaric acid B suppresses NSCLC progression through the ROS/AMPK/mTOR/autophagy signalling pathway.
Biomed Pharmacother: 2024, 175;116614
[PubMed:38670047] [WorldCat.org] [DOI] (I a)

Ke Yang, Jun-Qi Wang, Kai Li, Su-Ning Chen, Fei Yu
Pseudolaric acid B induces apoptosis associated with the mitochondrial and PI3K/AKT/mTOR pathways in triple‑negative breast cancer.
Oncol Rep: 2023, 50(5);
[PubMed:37711030] [WorldCat.org] [DOI] (I p)

Zhen Li, Bin Zhu, Weiqin Chen, Jun Hu, Yingjun Xue, Hongmei Yin, Xiaobo Hu, Weiwei Liu
##Title##
Infect Drug Resist: 2023, 16;5953-5964
[PubMed:37700797] [WorldCat.org] [DOI] (P e)

Zhanxu Liu, Nanya Wang, Zhaoli Meng, Shiying Lu, Gong Peng
Pseudolaric acid B triggers cell apoptosis by activating AMPK/JNK/DRP1/mitochondrial fission pathway in hepatocellular carcinoma.
Toxicology: 2023, 493;153556
[PubMed:37244295] [WorldCat.org] [DOI] (I p)

Bin Zhu, Zhen Li, Hongmei Yin, Jun Hu, Yingjun Xue, Guanyi Zhang, Xin Zheng, Weiqin Chen, Xiaobo Hu
Synergistic Antibiofilm Effects of Pseudolaric Acid A Combined with Fluconazole against Candida albicans via Inhibition of Adhesion and Yeast-To-Hypha Transition.
Microbiol Spectr: 2022, 10(2);e0147821
[PubMed:35297651] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects