Pseudolarix kaempferi

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Nomenclature

Other Names:

Historical Use of Pseudolarix kaempferi

Pseudolarix kaempferi in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Tujingpi

Chinese Name  :

Common Name  :Golden Larch Bark

Specific Name  : Cortex pseudolaricis

Scientific Name:
Collection  : The drug is collected in summer and dried in the sun.

Description  : Root bark irregularly long slat-shape, twisted and slightly rolled, variable in size, 2-5mm thick. Outer surface greyish yellow, rough wrinkled and greyish white transversely lenticelllate and the rugged external tissues frequently scaling off with reddish brown expose surface. Inner surface yellowish brown to reddish-brown, even with fine longitudinal striations. Texture flexible, fracture splintery, easily detachable in flakes. Odour slight, taste bitter and astringent, stem bark in flattish pieces up to about 8mm thick, the rugged external tissues relativerly thick, the outer surface cracked and the inner surface relatively rough.

Identification  : Powder: Pale brown or brownish-red, stone cells abundant, subrectangular, subrounded or irregular branched 30-96µm in diameter containing yellowish brown masses. Most sieve cells in bundles, 20-40µm in diameter, numerous elliptical sieve areas scattered over the side walls, mucilage cells subrounded, 100-300µm in diameter. Resin cells longitudinally connected into tube form containing reddish brown to yellowish brown resinous matter. Sometimes with prisms of calcium oxalate embedded in them. Walls of cork cells slightly thick, some of them lignified and pitted.

Processing  : Wash clean, soften slightly, cut into slivers and dry in the sun.

Action  : To kill parasites and relieve itching.

Indication  : scabies, tinea

Precautions  :

Dosage  : Appropriate quantity soaked with vinegar or wine, or ground into powder and mixed with water to be apllied topically.

Storage  : Preserve in a dry place.

Synonymns for Pseudolarix kaempferi

Patent Medicines and Medicines with Multiple Ingredients that include Pseudolarix kaempferi

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Pseudolarix kaempferi in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Jiayi Chen, Rongxue Du, Wei Wang, Fang An, Lu Ye, Hong Chen, Tao Jiang, Tan Li, Jihong Zhao
The anti-inflammatory effects of Pseudorlaric acid D on atherosclerosis.
Biomed. Pharmacother.: 2020, 125;109993
[PubMed:32058223] [WorldCat.org] [DOI] (I a)

Su-Jung Choi, Chi-Hyun Ahn, In-Hyoung Yang, Bohwan Jin, Won Woo Lee, Ji-Hoon Kim, Min-Hye Ahn, Neeti Swarup, Kyoung-Ok Hong, Ji-Ae Shin, Nam-Tae Woo, Seong Doo Hong, Jae-Il Lee, Sung-Dae Cho
Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5.
Molecules: 2019, 24(20);
[PubMed:31623058] [WorldCat.org] [DOI] (I e)

Hai Zhang, Jia-Chuan Li, Han Luo, Lin Zhao, Zhi-Dan Zhang, Xiao-Fei Shen
Pseudolaric acid B exhibits anti-cancer activity on human hepatocellular carcinoma through inhibition of multiple carcinogenic signaling pathways.
Phytomedicine: 2019, 59;152759
[PubMed:31004883] [WorldCat.org] [DOI] (I p)

Yue Wang, Hongmei Gao, Ting Wu, Zengyan Wang, Fengmei Song, Antian Chen, Jing Zhang, Wenyan Zhang, Hui Zhang, Jinghua Yu
Pseudolaric acid B induced autophagy, but not apoptosis, in MRC5 human fibroblast cells.
Oncol Lett: 2018, 15(1);863-870
[PubMed:29399151] [WorldCat.org] [DOI] (P p)

Zhen Yang, Meilun Liu, Wei Wang, Yiteng Wang, Bo Cao, Ying Gao, Hong Chen, Tan Li
Pseudolaric acid B attenuates atopic dermatitis-like skin lesions by inhibiting interleukin-17-induced inflammation.
Sci Rep: 2017, 7(1);7918
[PubMed:28801611] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects