Pepper is a non-scientific common name that may refer to a number of plant species and varieties.
Historical Use of Pepper
Pepper in Traditional Chinese Medicine
Historical Use of Pepper in Western Medicine
Quote Paraph: "The inhalation of fumes from a mixture of myrrh, ginger, pepper, ammonium salts and black cumin was recommended, as an additional way of administering anti-epileptic substances analogous to the way Avicenna said the ancient Greeks treated the disorder by inhalation of the fumes of the peony flower."
Sec Auth: Eadie MJ and Bladin PF
Title: A Disease Once Sacred. John Libbey & Company Ltd, 2001
Source: A Disease Once Sacred, John Libbey & Company Ltd, 2001, M.J. Eadie and P.F. Bladin
Complete: Eadie MJ, Bladin PF. A disease once sacred: a history of the medical understanding of epilepsy. Eastleigh: John Libbey; 2001. p. 177.
Synonymns for Pepper
Patent Medicines and Medicines with Multiple Ingredients that include Pepper
Evidence or the Use of Pepper in the Treatment of Epilepesy
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
1st Five Results: pubmed search
Dan Zhu, Wei-Guang Zhang, Xue-Dan Nie, Si-Wen Ding, Dong-Tai Zhang, Lei Yang
Rational design of ultra-small photoluminescent copper nano-dots loaded PLGA micro-vessels for targeted co-delivery of natural piperine molecules for the treatment for epilepsy.
J. Photochem. Photobiol. B, Biol.: 2020, 205;111805
Mario Mastrangelo, Chiara Alfonsi, Isabella Screpanti, Laura Masuelli, Barbara Tavazzi, Davide Mei, Flavia Giannotti, Renzo Guerrini, Vincenzo Leuzzi
Broadening phenotype of adenylosuccinate lyase deficiency: A novel clinical pattern resembling neuronal ceroid lipofuscinosis.
Mol Genet Metab Rep: 2019, 21;100502
Tianjing Ren, Min Xiao, Mengbi Yang, Jiajia Zhao, Yufeng Zhang, Mengyun Hu, Yan Cheng, Hong Xu, Chunbo Zhang, Xiaoyu Yan, Zhong Zuo
Reduced Systemic and Brain Exposure with Inhibited Liver Metabolism of Carbamazepine After Its Long-Term Combination Treatment with Piperine for Epilepsy Control in Rats.
AAPS J: 2019, 21(5);90
Tianjing Ren, Mengyun Hu, Yan Cheng, Tsum Lam Shek, Min Xiao, Nicolas James Ho, Chunbo Zhang, Sharon Shui Yee Leung, Zhong Zuo
Piperine-loaded nanoparticles with enhanced dissolution and oral bioavailability for epilepsy control.
Eur J Pharm Sci: 2019, 137;104988
Tianjing Ren, Mengbi Yang, Min Xiao, Junjie Zhu, Wen Xie, Zhong Zuo
Time-dependent inhibition of carbamazepine metabolism by piperine in anti-epileptic treatment.
Life Sci.: 2019, 218;314-323
Side Effect and Warnings
Pregnancy and Breastfeeding