Echinops latifolius

From Epilepsy Naturapedia
Jump to: navigation, search
P476 2.jpg
P476 1.jpg
Tcm p5514 01 005.jpg

Nomenclature

Other Names:

Historical Use of Echinops latifolius

Echinops latifolius in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Yuzhou Loulu

Chinese Name  :

Common Name  :Broadleaf Globethistle Root

Specific Name  : Radix echinopsis

Scientific Name:
Collection  : The drug is collected in spring or autumn, removed from rootlets and dried.

Description  : Subcylindrical, slightly tortous, 10 - 25 cm long. 0.5 - 1.5cm in diameter. Externally greyish yellow or greyish-brown, wrinkled longitudinally, top brown fibrous rigid hairy. Texture hard, uneasily broken, fracture bark brown, wood showing radial striations, coloured in yellow alternating with black. Odour slight, taste slightly astringent.

Identification  : Powder: Brownish yellow, phloem fibres in bundles, 20 - 42 µm in diameter with thickened walls, the interspaces of cells containing brown resinous substance. Xylem fibres slender, acuminate at two ends, 12 - 30 µm in diameter, walls relatively thick. Bordered pitted vessels and reticulated vessels more frequent, 20 - 120µm in diameter. Stone cells less frequent, subrounded, rectangular or square. 35 - 150 µm in diameter, markedly striated and pitted canalled. The interspaces of stone cells containing brown resinous substance. Inulin visible.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To remove heat and counteract toxicity, drainage of pus, stanch bleeding, to cure sores and carbuncles, increase the secretion of milk.

Indication  : carbuncle; mastitis with swelling and pain; galactostasis; scrofula and ulcers; ascariasis

Precautions  : Contraindicated in pregnancy.

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a ventilated dry place.

P476 2.jpg
P476 1.jpg
Tcm p5514 01 005.jpg

Nomenclature

Other Names:

Historical Use of Echinops latifolius

Echinops latifolius in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Loulu

Chinese Name  :

Common Name  :Uniflower Swisscentaury

Specific Name  : Radix rhapontici

Scientific Name:
Collection  : The drug is collected in spring and autumn, removed from rootlet and soil and dried in the sun.

Description  : Conical or flatted lumps, mostly twisted, varying in length, 1-2 cm in diameter. Externally greyish brown or dark brown, rough with longitudinal furrows and rhombic, netted clefts. Outer bark easily exfoliated. Root stock swollen with the remains of the stem and scaly leaf bases, top with greyish white pubescents. Texture light, fragile, easily broken, fracture irregular, greyish yellow, cleft, greyish black or brownish black in the center. Odour characteristic, taste slightly bitter.

Identification  : To 1 g of the powder add 20 ml of methanol, ultra-sonicate for 20 minutes, filter, evaporate the filtrate on a water bath to dryness. Dissolve the residue in 1 ml of ethyl acetate and use it as the test solution. Prepare a solution of Radix Rhpontici reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G as the coating substance and cyclohexane butanone (4:1) as the mobile phase. Apply separately 5 µl of each of the two solutions to the plate. After developing and removal of the plate, dry it in the air. Examine under ultra violet light (365 nm). A spot in the chromatogram obtained from the test solution correspond in color to the spot in the chromatogram obtained from the reference drug solution.

Processing  : Eliminate foreign matter, wash, clean soften thoroughly, cut into thick slices and dry in the sun.

Action  : To remove toxic heat for treating subcutaneous infections, to promote lactation, and to relieve muscular contracture.

Indication  : mastitis with swelling and pain, carbuncle, scrofula and ulcers; galactostasis; arthritis with ankylosis

Precautions  : Used with caution in pregnancy.

Dosage  : 5 to 9 g.

Storage  : Preserve in a ventilated and dry place.

Synonymns for Echinops latifolius

Patent Medicines and Medicines with Multiple Ingredients that include Echinops latifolius

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Echinops latifolius in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Qinghao Jin, Jin Woo Lee, Hari Jang, Ji Eun Choi, Hyung Sik Kim, Dongho Lee, Jin Tae Hong, Mi Kyeong Lee, Bang Yeon Hwang
Corrigendum to "Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius" [Bioorg. Med. Chem. Lett. 26 (2016) 5995-5998].
Bioorg. Med. Chem. Lett.: 2017, 27(6);1490
[PubMed:28202326] [WorldCat.org] [DOI] (I p)

Qinghao Jin, Jin Woo Lee, Hari Jang, Ji Eun Choi, Hyung Sik Kim, Dongho Lee, Jin Tae Hong, Mi Kyeong Lee, Bang Yeon Hwang
Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius.
Bioorg. Med. Chem. Lett.: 2016, 26(24);5995-5998
[PubMed:27865705] [WorldCat.org] [DOI] (I p)

Cheng-Gui Miao, Guo-Liang Zhou, Mei-Song Qin, Jian-Zhong Chen, Cheng-Feng Li, Bing Zhang
[Treatment of rheumatoid arthritis with flavonoids of Echinps latifolius Tausch in rat model].
Zhejiang Da Xue Xue Bao Yi Xue Ban: 2015, 44(1);43-8
[PubMed:25851974] [WorldCat.org] (P p)

Yi Wang, Xian Li, Lin-Hao Li, Da-Li Meng, Zhan-Lin Li, Ning Li
Two new thiophenes from Echinops latifolius and their phototoxic activities.
Planta Med.: 2007, 73(7);696-8
[PubMed:17564953] [WorldCat.org] [DOI] (P p)

Y Wang, X Li, D-L Meng, Z-L Li, P Zhang, J Xu
Thiophenes from Echinops latifolius.
J Asian Nat Prod Res: 2006, 8(7);585-8
[PubMed:17135040] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects