Choerospondias axillaris

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Nomenclature

Other Names:

Historical Use of Choerospondias axillaris

Choerospondias axillaris in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Guangzao

Chinese Name  :

Common Name  :Axillary Choerospondias Fruit

Specific Name  : Fructus choerospondiatis

Scientific Name:
Collection  : The drug is collected in autumn when ripe, removed from foreign matter and dried.

Description  : Ellipsoid or subovoid, 2 - 3cm. 1.4 - 2 cm in diameter. Externally blackish brown or brown, somewhat lustrous, irregularly shrunken, showing a fruit stalk scar at the base. Pulp thin, brown. Texture hard and brittle. Kernel subovoid, yellowish brown, apex having 5 ocassionally 4 or 6 distinct small holes, each possessing a seed. Odorless, taste sour.

Identification  : 1.Powder: Brown, stone cells of endocarp subrounded, elliptical, fusiform, rectangular or irregular, some elongated to fibre like or branched, 14 - 72µm in diameter, 25 - 294µm long with thickened walls and distinct pit canals, lumina containing pale yellowish brown contents. Fibres oof endocarp lignified with thickened or slightly thickened walls, crisscross arranged and some of lumina containing yellowish brown contents. Cells of exocarp subpolygonal in lateral view, containing brown contents and subrectangular in lateral view, radially elongated, the outer and redial walls cutinized-thickened. Parenchymatous cells of mesocarp containing cluster and few prisms of calcium oxalate, the clusters, 17 - 42µm in diameter, prisms rhomboid or irregular, 10 - 48µm long, 7 - 27µm in diameter.2.To 1g of the powder add 10ml of methanol, heat under reflux for 10 minutes, filter. Spot the filtrate on a piece of filter paper, spray with 0.05% solution of bromophenolblue in ethanol, a yellow color is produced on a blue background.3.To 2g of the powder add 20ml of 70% ethanol, heat under reflux for 15 minutes, filter. Evaporate the filtrate to dryness, dissolve the residue in 10ml of ethyl acetate and filter. Evaporate 1ml of the filtrate to dryness in a porcelain dish, add 1ml of saturated solution of boric acid in acetone and 1ml of 10% citric acid solution in acetone, a yellow color is produced. Evaporate the solution to dryness. Observe under ultra violet light (365nm), a yellowish green fluorescence is shown. Evaporate another 1ml of the filtrate to dryness, dissolve the residue in 1ml of methanol, add 3 - 4 drops of aluminum chloride TS, the yellow color becomes slightly deep. Spot the solution to a piece of filter paper, examine under ultra violet light (365nm), a yellow green fluorescence is shown.

Processing  :

Action  : To promote the flow of qi and blood, to replenish the heart and allay excitement.

Indication  : stagnation of qi and blood with chest pain, palpitation, shortness of breath, preoccupation

Precautions  :

Dosage  : 1.5 to 2.5 g.

Storage  : Preserve in a cool and dry place.

Synonymns for Choerospondias axillaris

Patent Medicines and Medicines with Multiple Ingredients that include Choerospondias axillaris

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Choerospondias axillaris in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Tong Jiang, Xin-Lin Lyu, Xiang-Wei Li, Zi-Yang Li, Dan Yang, Zi-Long Zhang, Jing-Jing Zhu, Zhi-Min Wang, Zhi-Gao Liu, Ji-Yan Liu
[Comparative of functional components, antioxidant and α-glucosidase inhibition activities between Choerospondias axillaris fruit peel vinegar and apple vinegar].
Zhongguo Zhong Yao Za Zhi: 2020, 45(5);1180-1187
[PubMed:32237463] [WorldCat.org] [DOI] (P p)

Yun-Seo Kil, April L Risinger, Cora L Petersen, Huiyun Liang, Tanja Grkovic, Barry R O'Keefe, Susan L Mooberry, Robert H Cichewicz
##Title##
J. Nat. Prod.: 2020, 83(3);584-592
[PubMed:32105068] [WorldCat.org] [DOI] (I p)

Zhancui Dang, Shanshan Su, Guoen Jin, Xingmei Nan, Lan Ma, Zhanqiang Li, Dianxiang Lu, Rili Ge
Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat.
J Ethnopharmacol: 2020, 250;112470
[PubMed:31862407] [WorldCat.org] [DOI] (I p)

Sonia Mann, Ankita Sharma, Ashish Sarkar, Rupsi Kharb, Rajesh Malhotra, Barun Datta, Rajinder K Gupta, Sagarika Biswas
Evaluation of anti-inflammatory effects of Choerospondias axillaris fruit's methanolic extract in synoviocytes and CIA rat model.
Curr Pharm Biotechnol: 2019;
[PubMed:31820687] [WorldCat.org] [DOI] (I a)

Qian Li, Chengmei Liu, Ti Li, David Julian McClements, Yinxin Fu, Jiyan Liu
Comparison of phytochemical profiles and antiproliferative activities of different proanthocyanidins fractions from Choerospondias axillaris fruit peels.
Food Res. Int.: 2018, 113;298-308
[PubMed:30195524] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects