Broussonetia papyrifera

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Nomenclature

Other Names:

Historical Use of Broussonetia papyrifera

Broussonetia papyrifera in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Chushizi

Chinese Name  :

Common Name  :Pappermulberry fruit

Specific Name  : Fructus broussonetiae

Scientific Name:
Collection  : The drug is collected in autumn when ripe, wash clean, dried in the sun, removed from greyish white, membranous oersistent calyx and foreign matter.

Description  : Somewhat spherical or ovoid, slightly flattened, about 1.5mm in diameter. Externally reddish brown, showing reticulated wrinkles or grandular prominences with ridges on one side and furrows on the other side some bearing fruit stalk. Texture hard and brittle, easily pressed to break. Endosperm almost white oily, odorless and taste weak.

Identification  : Powder: reddish brown, palisade cell walls of pericarp mucilaginous, remaining denticulate, striate thickened part, fine awn like in shape. Crystaliferous sclenal in surface view, containing clusters of calcium oxalate, subrectangular in section view, inner walls extremely thickened, lumina situated along outside, clusters oblong. Sclerenchymatous cells of endocarp extremely flattened, frequently overlapped in many layers with indistinct boundary. Epidermal cells of testa polygonal in surface view with slight beaded, unlignified walls and yellowish brown content containing lumina.Total ash: not more than 8.0%

Processing  :

Action  : To replenish the kidney, to subdue hyperactivity of the liver, to clear the eye of opacity, and to cause diuresis.

Indication  : aching and weakness of the loins and knees, consumptive fever, dizziness and blurred vision; nebula; edema

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a dry place, protected from moth.

Synonymns for Broussonetia papyrifera

Patent Medicines and Medicines with Multiple Ingredients that include Broussonetia papyrifera

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Broussonetia papyrifera in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Qi Wang, Yunfei Wei, Yeling Wang, Ziyang Yu, Haiyan Qin, Lilei Zhao, Jiaqi Cheng, Bingyu Shen, Meiyu Jin, Haihua Feng
Total flavonoids of Broussonetia papyrifera alleviate non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signaling pathways.
Biochim Biophys Acta Mol Cell Biol Lipids: 2024, 1869(5);159497
[PubMed:38649009] [WorldCat.org] [DOI] (I a)

Xiangqi Fan, Wei Yu, Qingxiang Wang, Heng Yang, Dayan Tan, Bing Yu, Jun He, Ping Zheng, Jie Yu, Junqiu Luo, Yuheng Luo, Hui Yan, Jianping Wang, Huifen Wang, Quyuan Wang, Xiangbing Mao
Protective effect of Broussonetia papyrifera leaf polysaccharides on intestinal integrity in a rat model of diet-induced oxidative stress.
Int J Biol Macromol: 2024, 268(Pt 1);131589
[PubMed:38643924] [WorldCat.org] [DOI] (I a)

Qiangwen Chen, Changye Zhu, Longfei Guo, Xianchen Bu, Wei Yang, Shuiyuan Cheng, Xin Cong, Feng Xu
Genome-wide identification of HMT gene family explores BpHMT2 enhancing selenium accumulation and tolerance in Broussonetia papyrifera.
Tree Physiol: 2024, 44(4);
[PubMed:38498335] [WorldCat.org] [DOI] (I p)

Shuyan Li, Xiongxiong Li, Yuzhu Sha, Shuai Qi, Xia Zhang, Huning Wang, Zhengwen Wang, Shengguo Zhao, Ting Jiao
Effects of Isochlorogenic Acid on Ewes Rumen Fermentation, Microbial Diversity and Ewes Immunity of Different Physiological Stages.
Animals (Basel): 2024, 14(5);
[PubMed:38473100] [WorldCat.org] [DOI] (P e)

Ahmad Kakakhail, Aimal Rextin, Jeroen Buters, Chun Lin, José M Maya-Manzano, Mehwish Nasim, Jose Oteros, Antonio Picornell, Hillary Pinnock, Jurgen Schwarze, Osman Yusuf
Predicting the main pollen season of Broussonetia Papyrifera (paper mulberry) tree.
PLoS One: 2024, 19(2);e0296878
[PubMed:38306347] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects