Broussonetia papyrifera

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Other Names:

Historical Use of Broussonetia papyrifera

Broussonetia papyrifera in Traditional Chinese Medicine


Chinese Name (pinyin): Chushizi

Chinese Name  :

Common Name  :Pappermulberry fruit

Specific Name  : Fructus broussonetiae

Scientific Name:
Collection  : The drug is collected in autumn when ripe, wash clean, dried in the sun, removed from greyish white, membranous oersistent calyx and foreign matter.

Description  : Somewhat spherical or ovoid, slightly flattened, about 1.5mm in diameter. Externally reddish brown, showing reticulated wrinkles or grandular prominences with ridges on one side and furrows on the other side some bearing fruit stalk. Texture hard and brittle, easily pressed to break. Endosperm almost white oily, odorless and taste weak.

Identification  : Powder: reddish brown, palisade cell walls of pericarp mucilaginous, remaining denticulate, striate thickened part, fine awn like in shape. Crystaliferous sclenal in surface view, containing clusters of calcium oxalate, subrectangular in section view, inner walls extremely thickened, lumina situated along outside, clusters oblong. Sclerenchymatous cells of endocarp extremely flattened, frequently overlapped in many layers with indistinct boundary. Epidermal cells of testa polygonal in surface view with slight beaded, unlignified walls and yellowish brown content containing lumina.Total ash: not more than 8.0%

Processing  :

Action  : To replenish the kidney, to subdue hyperactivity of the liver, to clear the eye of opacity, and to cause diuresis.

Indication  : aching and weakness of the loins and knees, consumptive fever, dizziness and blurred vision; nebula; edema

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a dry place, protected from moth.

Synonymns for Broussonetia papyrifera

Patent Medicines and Medicines with Multiple Ingredients that include Broussonetia papyrifera

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Broussonetia papyrifera in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Hui Tao, Bingwen Si, Wencai Xu, Yan Tu, Qiyu Diao
Effect of Broussonetia papyrifera L. silage on blood biochemical parameters, growth performance, meat amino acids and fatty acids compositions in beef cattle.
Asian-australas. J. Anim. Sci.: 2019;
[PubMed:32054236] [] [DOI] (P a)

Youfa Luo, Xingyu Wu, Hang Sun, Yonggui Wu
Root-induced changes in aggregation characteristics and potentially toxic elements (PTEs) speciation in a revegetated artificial zinc smelting waste slag site.
Chemosphere: 2020, 243;125414
[PubMed:31783184] [] [DOI] (I p)

Sana Qazi, Javed Iqbal, Junaid Aziz Khan
Assessment of the health impact of paper mulberry (Broussonetia papyrifera L.), an invasive plant species in Islamabad, Pakistan.
Geospat Health: 2019, 14(2);
[PubMed:31724384] [] [DOI] (I e)

Ayman Khamis Elsayed, Junichi Yukawa, Makoto Tokuda
Two new species of Schizomyia (Diptera: Cecidomyiidae) from Japan, with an updated key to larval, pupal and adult Schizomyia in Japan.
Zootaxa: 2019, 4688(3);zootaxa.4688.3.2
[PubMed:31719436] [] [DOI] (I e)

Hyung Won Ryu, Mi Hyeon Park, Ok-Kyoung Kwon, Doo-Young Kim, Jung-Yeon Hwang, Yang Hee Jo, Kyung-Seop Ahn, Bang Yeon Hwang, Sei-Ryang Oh
Anti-inflammatory flavonoids from root bark of Broussonetia papyrifera in LPS-stimulated RAW264.7 cells.
Bioorg. Chem.: 2019, 92;103233
[PubMed:31518759] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects