Belamcanda chinensis

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Nomenclature

Other Names:

Historical Use of Belamcanda chinensis

Belamcanda chinensis in Traditional Chinese Medicine

Background

Sheganpian Éä¸ÉƬ Chinese Name (pinyin): Shegan

Chinese Name  :

Common Name  :Belamcanda Rhizome

Specific Name  : Rhizoma belamcandae

Scientific Name:
Collection  : The drug is collected in early spring while the plant budding or in the late autumn while the aerial part withering, removed from the fibrous root and soil and dried.

Description  : Irregularly nodular, 3 - 10 cm long, 1 - 2 cm in diameter. Externally yellowish brown, dark brown or blackish brown, shrunken with abundantly annular striations. Several dish shaped and sunken stem scars occurring at the upper part, stem bases remained occasionally, remains of thin roots and root scars occurring at the lower part. Texture hard, fracture yellow, granular, odour slight, taste bitter and slightly pungent.

Identification  : 1. Transverse section: Epidermis sometimes remaining. Cork containing of more layers of cells. Cortex sparsely scattered with leaf trace bundles, endodermis indistinct. Vascular bundles of stele amphivasal and collateral, densely arranged near the outer side parenchymatous cells containing columnar crystal of calcium oxalate, starch granules and oil drops.Powder: Orange, crystal of calcium oxalate abundant, columnar, often broken, the intact ones 49 - 240 -315 µm long, up to 49 µm in diameter. Simple starch granules sub rounded or elliptical, 2 - 17 µm in diameter, hilum dotted compound granules very occasional composed of 2- 5 components. Parenchymatous cells sub rounded or ellipsoidal, walls slightly thickened or beaded with simple pits. Cork cells brown, polygonal in surface view, walls thin and slightly sinuous, some containing brown contents.3.To 1 g of the powder add 10 ml of methanol, ultrasonicate for 30 minutes, filter evaporate the filtrate to 1.5 ml and use it as the test solution. Prepare a solution of Rhizoma Belamcandae reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using polyamide film as the coating substance and chloroform-methanol-butanone (3:1:1) as the mobile phase. Apply separately 1 µl of each of the above two solutions to the film. After developing and removal of the membrane, dry it in the air, spray with aluminum chloride TS. Examine under ultra violet light (365 nm). The fluorescent spots in the chromatogram obtained with the test solution correspond in position and color to the spots in the chromatogram obtained with the reference drug solution.Extractives: Carry out the method for determination of extractives (Appendix X A, determination of ethanol soluble extractives), hot extraction method, not less than 18.0%

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thin slices and dry. In irregular or long slat shape, fracture yellow or brownish yellow. Carry out the determination of extractives as described above, not less than 18.0%.

Action  : To remove toxic heat, eliminate phlegm, and soothe the sore throat.

Indication  : sore throat, cough and dyspnea with copious expectoration due to accumulation of toxic heat, phlegm and fire

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a dry place.

Synonymns for Belamcanda chinensis

Patent Medicines and Medicines with Multiple Ingredients that include Belamcanda chinensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Belamcanda chinensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Cheng-Chuang Lin, Yuan-Yuan Wang, Si-Min Chen, Yun-Tao Liu, Ji-Qiang Li, Fang Li, Jie-Chen Dai, Tong Zhang, Feifei Qiu, Huazhen Liu, Zhenhua Dai, Zhong-De Zhang
Shegan-Mahuang Decoction ameliorates asthmatic airway hyperresponsiveness by downregulating Th2/Th17 cells but upregulating CD4+FoxP3+ Tregs.
J Ethnopharmacol: 2020, 253;112656
[PubMed:32035217] [WorldCat.org] [DOI] (I a)

Etta Y Liu, Zoey X Zheng, Brody Z Zheng, Yingjie Xia, Maggie S Guo, Tina T Dong, Karl W K Tsim
Tectorigenin, an isoflavone aglycone from the rhizome of Belamcanda chinensis, induces neuronal expression of erythropoietin via accumulation of hypoxia-inducible factor-1α.
Phytother Res: 2019;
[PubMed:31845440] [WorldCat.org] [DOI] (I a)

Dongjin Noh, Jin Gyu Choi, Young Bae Lee, Young Pyo Jang, Myung Sook Oh
Protective effects of Belamcandae Rhizoma against skin damage by ameliorating ultraviolet-B-induced apoptosis and collagen degradation in keratinocytes.
Environ. Toxicol.: 2019, 34(12);1354-1362
[PubMed:31436008] [WorldCat.org] [DOI] (I p)

Jiayuan Li, Gang Ni, Yanfei Liu, Zhenpeng Mai, Renzhong Wang, Dequan Yu
##Title##
J. Nat. Prod.: 2019, 82(7);1759-1767
[PubMed:31246464] [WorldCat.org] [DOI] (I p)

Shui Liu, Jianfeng Wang, Jian Zhang, Tingting Wang, Yonglin Zhou, Qianghua Lv, Naiyu Hu, Xue Shen, Xuming Deng
Tectorigenin reduces type IV pilus-dependent cell adherence in Clostridium perfringens.
FEMS Microbiol. Lett.: 2019, 366(10);
[PubMed:31125043] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects