Ziziphus inermis

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Other Names:

Historical Use of Ziziphus inermis

Ziziphus inermis in Traditional Chinese Medicine


Hongzao ºìÔæ Chinese Name (pinyin): Dazao

Chinese Name  :

Common Name  :Chinese Date

Specific Name  : Fructus jujubae

Scientific Name:
Collection  : The drug is collected in autumn when ripe and dried in the sun.

Description  : Ellipsoidal or spheroidal, 2 - 3.5cm long, 1.5 - 2.5cm in diameter. Externally dark red, somewhat lustrous, irregularly wrinkled. Base dented with a short fruit stalk. Axocarp thin, mesocarp brownish yellow or pale brown, fleshy, soft, sugary and oily. Kernel fusiform, acute at the both ends, texture hard, odor slightly aromatic and taste sweet.Total ash: not more than 2.0%

Identification  :

Processing  : Eliminate foreign matter, wash clean, dry in the sun. Cut or remove the kernel before use.

Action  : To tonify the spleen and replenish qi, to nourish blood, and to ease the mind.

Indication  :

Precautions  :

Dosage  : 6 to 15 g.

Storage  : Preserve in a dry place, protected from moth.

Synonymns for Ziziphus inermis

Patent Medicines and Medicines with Multiple Ingredients that include Ziziphus inermis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Ziziphus inermis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Huynh Nguyen Khanh Tran, Thao Quyen Cao, Jeong Ah Kim, Mi Hee Woo, Byung Sun Min
Anti-inflammatory and cytotoxic activities of constituents isolated from the fruits of Ziziphus jujuba var. inermis Rehder.
Fitoterapia: 2019, 137;104261
[PubMed:31284019] [WorldCat.org] [DOI] (I p)

Maryam Mardani, Parisa Badiee, Mahnaz Gharibnavaz, AmirReza Jassebi, Hadis Jafarian, Fatemeh Ghassemi
J Conserv Dent: 2018, 21(4);359-362
[PubMed:30122813] [WorldCat.org] [DOI] (P p)

Minna Shin, Bo-Mi Lee, Okwha Kim, Huynh Nguyen Khanh Tran, Suhyun Lee, Cheol Hwangbo, Byung-Sun Min, Jeong-Hyung Lee
Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production.
Food Funct: 2018, 9(7);3895-3905
[PubMed:29968885] [WorldCat.org] [DOI] (I p)

Sameh S M Soliman, Mohammad H Semreen, Ali A El-Keblawy, Arbab Abdullah, Priya Uppuluri, Ashraf S Ibrahim
Assessment of herbal drugs for promising anti-Candida activity.
BMC Complement Altern Med: 2017, 17(1);257
[PubMed:28482836] [WorldCat.org] [DOI] (I e)

Soojin Lee, Huijin Gim, Ji Hwan Shim, Hyun Jung Kim, Jong Rok Lee, Sang Chan Kim, Young Kyu Kwon, Ki-Tae Ha, Insuk So, Byung Joo Kim
The traditional herbal medicine, Ge-Gen-Tang, inhibits pacemaker potentials by nitric oxide/cGMP dependent ATP-sensitive K(+) channels in cultured interstitial cells of Cajal from mouse small intestine.
J Ethnopharmacol: 2015, 170;201-9
[PubMed:26003723] [WorldCat.org] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects