Whitmania acranulate

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Other Names:

Historical Use of Whitmania acranulate

Whitmania acranulate in Traditional Chinese Medicine


Chinese Name (pinyin): Shuizhi

Chinese Name  :

Common Name  :Leetch

Specific Name  : Hirudo

Scientific Name:
Collection  : The drug is collected in summer and autumn, scalded to death with boiling water, dried in the sun or at low temperature.

Description  : Body of Whitmania pigra: Flattened spindle shaped with a large number of segments, 4 - 10cm long, 0.5 - 2cm wide. Dorsal side blackish brown, slightly convex with black speckles forming 5 longitudinal stripes, ventral side even, brownish yellow, lateral sides brownish yellow. Anterior end somewhat pointed, posterior end blunt with a sucker at the anterior and posterior ends respectively. The anterior sucker inconspicious, the posterior sucker larger. Texture fragile, easily broken, fracture gelatinous, odour slightly stinking.

Identification  :

Processing  : Wash clean, cut into sections and dry.Scalded: Scald section of Hirudo with talc powder as described under the method for scalding (Appendix ll D) until it becomes slightly expanded.

Action  : To eliminate blood stasis and to stimulate menstrual discharge.

Indication  : mass formation in the abdomen, amenorrhea due to blood stasis; traumatic injuries

Precautions  : Contraindicated in pregnancy.

Dosage  : 1.5 to 3 g.

Storage  : Preserve in a dry place, protected from moth.

Synonymns for Whitmania acranulate

Patent Medicines and Medicines with Multiple Ingredients that include Whitmania acranulate

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Whitmania acranulate in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Xin Lu, Qiao-Sheng Guo, Hong-Zhuan Shi, Shuai Wang, Pan-Pan Chen, Hui-Ning Zhang, Xiao-Lu Yan
[Effects of MT on growth and gonad development of natural overwintering Whitmania pigra].
Zhongguo Zhong Yao Za Zhi: 2019, 44(20);4426-4432
[PubMed:31872628] [WorldCat.org] [DOI] (P p)

Junping Zheng, Man Chen, Cheng Ye, Xiongjie Sun, Nan Jiang, Xiaojuan Zou, Huabing Yang, Hongtao Liu
BuZangTongLuo decoction improved hindlimb ischemia by activating angiogenesis and regulating gut microbiota in diabetic mice.
J Ethnopharmacol: 2020, 248;112330
[PubMed:31654796] [WorldCat.org] [DOI] (I p)

Shuai Wang, Qiao-Sheng Guo, Hong-Zhuan Shi, Xin Lu, Pan-Pan Chen, Hui-Ning Zhang, Xiao-Lu Yan
[Effects of 17β-E2 on growth and gonad development of overwintering Whitmania pigra].
Zhongguo Zhong Yao Za Zhi: 2019, 44(15);3239-3245
[PubMed:31602878] [WorldCat.org] [DOI] (P p)

Shen-Hong Ren, Zhao-Jun Liu, Yuan Cao, Yi Hua, Cong Chen, Wei Guo, Yi Kong
A novel protease-activated receptor 1 inhibitor from the leech Whitmania pigra.
Chin J Nat Med: 2019, 17(8);591-599
[PubMed:31472896] [WorldCat.org] [DOI] (I p)

Xiao-Lan Yao, Han Liu, Peng Li, Wen-Pei Chen, Shi-Xia Guan, Yang Chen, Yi-Na Wu, Bao-Qin Lin
Aqueous Extract of Whitmania Pigra Whitman Alleviates Thrombus Burden Via Sirtuin 1/NF-κB Pathway.
J. Surg. Res.: 2020, 245;441-452
[PubMed:31445496] [WorldCat.org] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects