Vladimiria souliei

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Nomenclature

Other Names:

Historical Use of Vladimiria souliei

Vladimiria souliei in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Chuanmuxiang

Chinese Name  :

Common Name  :Common Vladimiriae root

Specific Name  : Radix vladimiriae

Scientific Name:
Collection  : The drug is collected in autumn , removed from rootlet, soil, and gelatinous matter on root stock and dried.

Description  : Cylindrical or semi cylindrical and longitudinally furrowed, somewhat curved, 10 - 30 cm long. 1 - 3 cm in diameter. Externally yellowish brown or deep brown, longitudinally wrinkled, showing numerous fine veins like vegetable sponge at the place where the outer bark fallen off. Root stock occasionally with black viscous gelatinous substance commonly known as "oil head". Relatively light, texture hard and fragile, easily broken, fracture yellowish white or yellow with sparsely scattered deep yellow oil dots and some clefts, wood broad with radial striations. Sometimes the central part rotten wood like odour, slightly aromatic, taste bitter, sticky on chewing.

Identification  : ransverse section: Cork consisting of several layers of brown cells. Phloem ray relatively broad, sieve tube groups and fibre bundles, alternately arranged with xylem vessels groups and fibre bundles, regularly radiated. Cambium ring undulated, fibre bundle yellow, lignified accompanied by stone cells. Pith present or withered. Oil cavities scattered in rays and throughout parenchyma in pith. Inulin visible in parenchymatous cells.Total ash: Not more than 4.0%

Processing  : Eliminate foreign matter and "oil head", wash clean, soften thoroughly cut into thick slices and dry.Roast: Spread several layers of rough paper made of straw in a wire shallow basket, put a layer of undried clean slices of Radix Vladimiriae on every layer of the paper, cover the slices with the paper, roast on a cook stove or in drying shed until the volatile oil is absorbed by the paper and take out and dry in the air

Action  : To promote the flow of qi and relieve pain.

Indication  : pain and distension in the epigastrium and abdomen with borborygmi, diarrhea, tenesms; discomfort int the hypochondriac regions, pain in the liver, diseases of the gall bladder

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a cool and dry place.

Synonymns for Vladimiria souliei

Patent Medicines and Medicines with Multiple Ingredients that include Vladimiria souliei

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Vladimiria souliei in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Robert A Hill, Andrew Sutherland
Hot off the press.
Nat Prod Rep: 2019, 36(2);258-262
[PubMed:30667456] [WorldCat.org] [DOI] (I p)

Jingxin Mao, Man Yi, Rui Wang, Yuanshe Huang, Min Chen
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Front Pharmacol: 2018, 9;1469
[PubMed:30618760] [WorldCat.org] [DOI] (P e)

Jingxin Mao, Man Yi, Yunyi Tao, Yuanshe Huang, Min Chen
Costunolide isolated from Vladimiria souliei inhibits the proliferation and induces the apoptosis of HepG2 cells.
Mol Med Rep: 2019, 19(2);1372-1379
[PubMed:30569137] [WorldCat.org] [DOI] (I p)

Zhi-Li Wu, Qun Wang, Jin-Xin Wang, Hong-Yuan Dong, Xi-Ke Xu, Yun-Heng Shen, Hui-Liang Li, Wei-Dong Zhang
Vlasoulamine A, a Neuroprotective [3.2.2]Cyclazine Sesquiterpene Lactone Dimer from the Roots of Vladimiria souliei.
Org. Lett.: 2018, 20(23);7567-7570
[PubMed:30421929] [WorldCat.org] [DOI] (I p)

Zhi-Li Wu, Qun Wang, Hong-Yuan Dong, Hui-Liang Li, Shu-Mei Wang, Wei-Dong Zhang
Five rare dimeric sesquiterpenes exhibiting potential neuroprotection activity from Vladimiria souliei.
Fitoterapia: 2018, 128;192-197
[PubMed:29782902] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects