Vitex rotundifolia

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Nomenclature

Other Names:

Historical Use of Vitex rotundifolia

Vitex rotundifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Manjingzi

Chinese Name  :

Common Name  :Fruit of Shrub Chastetree

Specific Name  : Fructus Viticis

Scientific Name:
Collection  : The drug is collected from autumn when ripe. Removed from foreign matter and dried in the sun.

Description  : Spheroidal, 4 - 6mm in diameter, externally greyish black or blackish brown, covered with greyish white frost like hairs, bearing 4 longitudinal shallow furrows, apex slightly concave with greyish white, persistent calyx and short fruit stalk at the base. Calyx is 1/3 - 2/3 length of the fruit, 5 toothed, 2 of them relatively deep, covered with densely pubescent. Texture light and hard, uneasily broken. Transverse section showing 4 loculi, each with one seed. Odour characteristic and aromatic, taste weak and slightly pungent.

Identification  : Powder: Greyish brown, epidermal cells of calyx subrounded, walls frequently sinous, non-glndular hairs 2 - 3 celled, apical cell relatively wide with warty protrudings. Cells of epicarp polygonal with cuticle striations and scar of the hairs bearing glandular hairs and non-glandular hairs in two types. One with a unicellular head and a 1 - 2 celled stalk and the other a 2 -6 celled, 14 - 68µm long, often curved, warty walled. Cells of mesocarp oblong or subrounded, walls slightly lignified and with distinct pits. Vittae frequently broken containing secretions, adjacent cells containing pale yellow oil droplets. Stone cells of endocarp elliptical or subsquare. 10 - 35µm in diameter. Cells of testa rounded or subrounded, 42 - 73µm in diameter with reticulate striated and lignified walls.

Processing  : Eliminate foreign matterStir fried: Clean, stir fry gently as describe under the method for simple stir frying (Appendix ll D), break to pieces before use.

Action  :

Indication  : headache in upper respiratory tract infection; painful swelling of the gums; inflammation of the eye with lacrimation, blurring of vision and dizziness

Precautions  :

Dosage  :

Storage  :

Synonymns for Vitex rotundifolia

Patent Medicines and Medicines with Multiple Ingredients that include Vitex rotundifolia

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Vitex rotundifolia in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Chinmoy Bhuyan, Dipankar Saha, Bipul Rabha
Repellent activity of Vitex negundo and Curcuma longa herbal extract against simulium species in India.
J Vector Borne Dis: 2024;
[PubMed:38634372] [WorldCat.org] [DOI] (I a)

Hyung-Mun Yun, Hyun Sook Kwon, Joon Yeop Lee, Kyung-Ran Park
Vitexicarpin Induces Apoptosis and Inhibits Metastatic Properties via the AKT-PRAS40 Pathway in Human Osteosarcoma.
Int J Mol Sci: 2024, 25(7);
[PubMed:38612399] [WorldCat.org] [DOI] (I e)

Imane Zoufri, Mohammed Merzouki, Malika Ammari, Younesse El-Byari, Mohamed Chedadi, Amina Bari, Fatima Zahra Jawhari
Performance of vertical flow constructed wetland for the treatment of effluent from a brassware industry in city of Fez, Morocco: a laboratory scale study.
Int J Phytoremediation: 2024;1-13
[PubMed:38591171] [WorldCat.org] [DOI] (I a)

Gunjan Garg, Alok Bharadwaj, Shweta Chaudhary, Veena Gupta
##Title##
World J Exp Med: 2024, 14(1);88064
[PubMed:38590309] [WorldCat.org] [DOI] (P e)

Tarun Kumar Kar, Sananda Sil, Angshita Ghosh, Ananya Barman, Sandip Chattopadhyay
Mitigation of letrozole induced polycystic ovarian syndrome associated inflammatory response and endocrinal dysfunction by Vitex negundo seeds.
J Ovarian Res: 2024, 17(1);76
[PubMed:38589892] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects