Viola yedoensis

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Other Names:

Historical Use of Viola yedoensis

Viola yedoensis in Traditional Chinese Medicine


Diding µØ¶¡ Chinese Name (pinyin): Zihuadiding

Chinese Name  :

Common Name  :Viola Herb

Specific Name  : Herba violae

Scientific Name:
Collection  : The drug is collected in spring and autum, removed from foreign matter and dried in the sun.

Description  : Frequently crumpled into masses. The main root long conical, 1 - 3mm in diameter, pale yellowish-brown with fine longitudinal wrinkles. Leaves basal, greyish green when whole, lanceolate or ovate lanceolate, 1.5 - 6cm long, 1 - 2cm wide, apex obtuse, base truncate or somewhat cordate, margins obtusely serrate, both surfaces pubescent, petioles slender, 2 - 6cm long, the upper part with distinct narrow wings. Pedicels slender, petals 5, purple or pale brown, hypanthium, slender tubular. Capsule elliptical or spliting into three, numerous seeds, pale brown, odour slight taste slightly bitter and sticky.

Identification  : Transverse section of leaf: The upper epidermal cells relatively large, tangentially elongated, the outer walls thickened and the inner walls mucilaginous, frequently swollen into semi circle. The lower epidermal cells smaller, occasionally having mucilage cells, the upper and lower epidermis bearing unicellular non-glandular hairs. 32 - 240µm long, 24 - 32µm in diameter with short cuticle striations. Palisade cells 2 - 3 rows, spongy cells, subcircular, containing cluster of calcium oxalate, 11 - 40µm in diameter. Midrib bundles collateral, the inner side of the upper and lower epidermis having 1 - 2 layers of collenchymatous cells.

Processing  : Eliminate foreign matter, wash, cut into pieces and dry.

Action  : To remove toxic heat, to reduce heat from blood, and to induce subsidence of swelling.

Indication  : carbuncles, boils, erysipelas and other cutaneous and subcutaneous pyogenic infections; venomous snake bite

Precautions  :

Dosage  : 15 to 30 g; for external use, appropriate quantity of the fesh herb to be pounded into paste and applied topically.

Storage  : Preserve in a dry place.

Synonymns for Viola yedoensis

Patent Medicines and Medicines with Multiple Ingredients that include Viola yedoensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Viola yedoensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Xinya Hemu, Abbas El Sahili, Side Hu, Kaho Wong, Yu Chen, Yee Hwa Wong, Xiaohong Zhang, Aida Serra, Boon Chong Goh, Dina A Darwis, Ming Wei Chen, Siu Kwan Sze, Chuan-Fa Liu, Julien Lescar, James P Tam
Structural determinants for peptide-bond formation by asparaginyl ligases.
Proc. Natl. Acad. Sci. U.S.A.: 2019, 116(24);11737-11746
[PubMed:31123145] [] [DOI] (I p)

Xiao-Lu Yan, Qiao-Sheng Guo, Hong-Zhuan Shi, Zhong-Yuan Shen, Yi Wang, Zai-Biao Zhu, Dan-Lan Zhai, Xiao-Hong Xie
[Effects of light intensities on growth,physiological characteristic and chemical composition of Viola yedoensis].
Zhongguo Zhong Yao Za Zhi: 2019, 44(6);1119-1125
[PubMed:30989973] [] [DOI] (P p)

She-Fang Huang, Shu-Chen Chu, Yi-Hsien Hsieh, Pei-Ni Chen, Yih-Shou Hsieh
Viola Yedoensis Suppresses Cell Invasion by Targeting the Protease and NF-κB Activities in A549 and Lewis Lung Carcinoma Cells.
Int J Med Sci: 2018, 15(4);280-290
[PubMed:29511364] [] [DOI] (I e)

Dong-Sheng Du, Zhi-Hong Cheng, Dao-Feng Chen
[Anti-complement alkaloids from whole plants of Viola yedoensis].
Zhongguo Zhong Yao Za Zhi: 2017, 42(24);4794-4800
[PubMed:29493149] [] [DOI] (P p)

Ya-Li Wang, Lin Zhang, Meng-Yan Li, Li-Wei Wang, Chao-Mei Ma
Nat. Prod. Res.: 2019, 33(11);1550-1555
[PubMed:29334261] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects