Viola yedoensis

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Nomenclature

Other Names:

Historical Use of Viola yedoensis

Viola yedoensis in Traditional Chinese Medicine

Background

Diding µØ¶¡ Chinese Name (pinyin): Zihuadiding

Chinese Name  :

Common Name  :Viola Herb

Specific Name  : Herba violae

Scientific Name:
Collection  : The drug is collected in spring and autum, removed from foreign matter and dried in the sun.

Description  : Frequently crumpled into masses. The main root long conical, 1 - 3mm in diameter, pale yellowish-brown with fine longitudinal wrinkles. Leaves basal, greyish green when whole, lanceolate or ovate lanceolate, 1.5 - 6cm long, 1 - 2cm wide, apex obtuse, base truncate or somewhat cordate, margins obtusely serrate, both surfaces pubescent, petioles slender, 2 - 6cm long, the upper part with distinct narrow wings. Pedicels slender, petals 5, purple or pale brown, hypanthium, slender tubular. Capsule elliptical or spliting into three, numerous seeds, pale brown, odour slight taste slightly bitter and sticky.

Identification  : Transverse section of leaf: The upper epidermal cells relatively large, tangentially elongated, the outer walls thickened and the inner walls mucilaginous, frequently swollen into semi circle. The lower epidermal cells smaller, occasionally having mucilage cells, the upper and lower epidermis bearing unicellular non-glandular hairs. 32 - 240µm long, 24 - 32µm in diameter with short cuticle striations. Palisade cells 2 - 3 rows, spongy cells, subcircular, containing cluster of calcium oxalate, 11 - 40µm in diameter. Midrib bundles collateral, the inner side of the upper and lower epidermis having 1 - 2 layers of collenchymatous cells.

Processing  : Eliminate foreign matter, wash, cut into pieces and dry.

Action  : To remove toxic heat, to reduce heat from blood, and to induce subsidence of swelling.

Indication  : carbuncles, boils, erysipelas and other cutaneous and subcutaneous pyogenic infections; venomous snake bite

Precautions  :

Dosage  : 15 to 30 g; for external use, appropriate quantity of the fesh herb to be pounded into paste and applied topically.

Storage  : Preserve in a dry place.

Synonymns for Viola yedoensis

Patent Medicines and Medicines with Multiple Ingredients that include Viola yedoensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Viola yedoensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Yan Mao, Xiangyi Kong, Zengenni Liang, Chenglin Yang, Siqi Wang, Hui Fan, Can Ning, Wenguang Xiao, You Wu, Jing Wu, Liyun Yuan, Zhihang Yuan
Viola yedoensis Makino alleviates heat stress-induced inflammation, oxidative stress, and cell apoptosis in the spleen and thymus of broilers.
J Ethnopharmacol: 2024, 319(Pt 3);117350
[PubMed:37907144] [WorldCat.org] [DOI] (I p)

Side Hu, Abbas El Sahili, Srujana Kishore, Yee Hwa Wong, Xinya Hemu, Boon Chong Goh, Sang Zhipei, Zhen Wang, James P Tam, Chuan-Fa Liu, Julien Lescar
Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase.
Plant Cell: 2022, 34(12);4936-4949
[PubMed:36099055] [WorldCat.org] [DOI] (I p)

Hairong Zeng, Bei Zhao, Die Zhang, Xin Rui, Xudong Hou, Xingxing Chen, Benrui Zhang, Yi Yuan, Hongping Deng, Guangbo Ge
Viola yedoensis Makino formula alleviates DNCB-induced atopic dermatitis by activating JAK2/STAT3 signaling pathway and promoting M2 macrophages polarization.
Phytomedicine: 2022, 103;154228
[PubMed:35689898] [WorldCat.org] [DOI] (I p)

Saeideh Saadat, Sima Beigoli, Mohammad Reza Khazdair, Fatemeh Amin, Mohammad Hossein Boskabady
Experimental and Clinical Studies on the Effects of Natural Products on Noxious Agents-Induced Lung Disorders, a Review.
Front Nutr: 2022, 9;867914
[PubMed:35662950] [WorldCat.org] [DOI] (P e)

Pei-Fang Yang, Hong-Zhuan Shi, Qiao-Sheng Guo, Kun Zhao, Li Liu
[Screening and validation of RT-qPCR reference genes of Viola yedoensis under different light intensities].
Zhongguo Zhong Yao Za Zhi: 2021, 46(21);5620-5626
[PubMed:34951215] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects