Verbena officinalis

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Other Names:

Historical Use of Verbena officinalis

Verbena officinalis in Traditional Chinese Medicine


Chinese Name (pinyin): Mabiancao

Chinese Name  :

Common Name  :European verbena herb

Specific Name  : Herba verbanae

Scientific Name:
Collection  : The drug is collected at flowering from June to August, remove from foreign matter and dried in the sun.

Description  : Stems square, frequently branched with longitudinal furrows on the four sides. 0.5 - 1m long, externally greenish brown, rough, texture hard and fragile, fracture medullated or hollowed. Leaves opposite crumpled and mostly broken, greenish brown when whole, lamina 3 partite, spike slender with numerous small flowers. Odorless and taste bitter.

Identification  : To 2g of the powder add 60ml of 80% methanol, heat under reflux on a water bath for 1 hour, filter, evaporate the filtrate to dryness. Dissolve the residue in 2ml of methanol and use it as the test solution. Prepare a solution of Herbe verbenae reference drug in the same manner as the reference drug solution. Dissolve oleanolic CRS to produce a solution containing 1mg per ml used as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G containing sodium carboxymethyl cellulose as the coating substance and chloroform-methanol-isopropanol (16:0.5:0.25 as the mobile phase. Apply separately to the plate 2 - 4µl each of the above three solutions. After developing and removal of the plate, dry it in the air, spray with a mixture of vanillin ethanol solution (1:100) and a water solution of perchloric acid (3:100) (mix in equal portions before use), dry it in the air until the colored spots appear clearly. A spot in the chromatogram obtained from the test solution corresponds in colour and position to the spot in the chromatogram obtained from the reference solution and the reference drug solution.

Processing  : Eliminate remain roots and foreign matter, wash clean, soften briefly, cut into sections and dry in the sun.

Action  : To promote the flow of blood and to relieve blood stasis, to stop malarial attacks, to counteract toxicity, and to cause diuresis.

Indication  : abdominal mass; amenorrhea and dysmenorrhea; malaria; throat inflammation, carbuncles, boils, urinary tract infection; edema

Precautions  :

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a dry place.

Synonymns for Verbena officinalis

Patent Medicines and Medicines with Multiple Ingredients that include Verbena officinalis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Verbena officinalis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Paweł Kubica, Agnieszka Szopa, Barbara Prokopiuk, Łukasz Komsta, Bożena Pawłowska, Halina Ekiert
The influence of light quality on the production of bioactive metabolites - verbascoside, isoverbascoside and phenolic acids and the content of photosynthetic pigments in biomass of Verbena officinalis L. cultured in vitro.
J. Photochem. Photobiol. B, Biol.: 2020, 203;111768
[PubMed:31931383] [] [DOI] (I p)

Nora Gibitz-Eisath, Miriam Eichberger, Regina Gruber, Christoph Seger, Sonja Sturm, Hermann Stuppner
Towards eco-friendly secondary plant metabolite quantitation: Ultra high performance supercritical fluid chromatography applied to common vervain (Verbena officinalis L.).
J Sep Sci: 2019;
[PubMed:31769179] [] [DOI] (I a)

Guan-Wen Chen, Tai-Yuan Chen, Pei-Ming Yang
Differential effect of herbal tea extracts on free fatty acids-, ethanol- and acetaminophen-induced hepatotoxicity in FL83B hepatocytes.
Drug Chem Toxicol: 2019;1-6
[PubMed:31736373] [] [DOI] (I a)

Mekonnen Sisay, Negussie Bussa, Tigist Gashaw, Getnet Mengistu
Investigating In Vitro Antibacterial Activities of Medicinal Plants Having Folkloric Repute in Ethiopian Traditional Medicine.
J Evid Based Integr Med: 2019, 24;2515690X19886276
[PubMed:31707813] [] [DOI] (I p)

Mekonnen Sisay, Negussie Bussa, Tigist Gashaw
J Evid Based Integr Med: 2019, 24;2515690X19853264
[PubMed:31204502] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects