Vaccaria segetalis

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Other Names:

Historical Use of Vaccaria segetalis

Vaccaria segetalis in Traditional Chinese Medicine


Buliuxing Íõ²»Áô Chinese Name (pinyin): Wangbuliuxing

Chinese Name  :

Common Name  :Vaccaria Seed

Specific Name  : Semen vaccariae

Scientific Name:
Collection  : The plant is collected in summer when the fruit is ripe but not dehiscent and dried in the sun. The seed is gathered, remove from foreign matter and dried again in the sun

Description  : Spheroidal about 2 mm in diameter. Externally black, a few in reddish brown, somewhat lustrous with fine and dense granular protuberance and concave longitudinal furrow on one side. Texture hard, endosperm white, embryo curved in a ring, 2 cotyledons. Odorless, taste slightly astringent and bitter.

Identification  : Powder: greyish brown. Epidermal cells of testa reddish brown or yellowish brown. Polygonal or elongated polygonal in surface view, 50 - 120µm in diameter, anticlinal walls thickened, stellate or sinuate. Inner epidermal cells of testa pale yellowish brown, subsquare or sub-rectangular or polygonal in surface view, anticlinal walls densely beaded, reticulated striations visible on surface. Endosperm cells polygonal, sub-square or surectangular. Lumina filled with starch granules and aleurone grains. Cotyledon cells containing fatty oil droplets.Total ash: Not more than 4.0% (Appendix lX K)

Processing  : Eliminate foreign matter.Stir fried: Stir fry as described under the method for simple stir frying (Appendix 11 D) until most of the seeds burst.

Action  : To promote the menstrual flow and the flow of milk, and to ause the subsidence of swelling.

Indication  : galactostasis, amenorrhea, dysmenorrhea, mastitis with swelling and pain

Precautions  : Used with caution in pregnancy.

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a dry place.

Synonymns for Vaccaria segetalis

Patent Medicines and Medicines with Multiple Ingredients that include Vaccaria segetalis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Vaccaria segetalis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Xin Mao, Hongling Guo, Rongmei Yao, Lei Bao, Jing Sun, Yanyan Bao, Bo Guo, Yingjie Gao, Yujing Shi, Haijiang Zhang, Xiaolan Cui
Crude polysaccharides from the seeds of Vaccaria segetalis prevent the urinary tract infection through the stimulation of kidney innate immunity.
J Ethnopharmacol: 2020;
[PubMed:31962152] [] [DOI] (I a)

Fei Xu, Bao Hou, Xuexue Zhu, Yixiao Liu, Xuelin Shi, Shuangshuang Li, Zhongjie Li, Weiwei Cai, Yuetao Zhou, Liying Qiu
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Acta Parasitol.: 2019, 64(3);520-527
[PubMed:31087260] [] [DOI] (I p)

Yun Liu, Fang-Ming Song, Shi-Ting Ma, Abu Moro, Wen-Yu Feng, Shi-Jie Liao, Xi-Xi Lin, Jin-Min Zhao, Zi-Yi Wang, Jiake Xu, Xin-Li Zhan, Qian Liu
Vaccarin prevents titanium particle-induced osteolysis and inhibits RANKL-induced osteoclastogenesis by blocking NF-κB and MAPK signaling pathways.
J. Cell. Physiol.: 2019, 234(8);13832-13842
[PubMed:30637734] [] [DOI] (I p)

Hongxi Chen, Tongya Guo, Dianrong Wang, Rujie Qin
Vaccaria hypaphorine impairs RANKL-induced osteoclastogenesis by inhibition of ERK, p38, JNK and NF-κB pathway and prevents inflammatory bone loss in mice.
Biomed. Pharmacother.: 2018, 97;1155-1163
[PubMed:29136954] [] [DOI] (I p)

Lei Su, Yan-Yan Jiang, Bin Liu
[Oligopeptides in plant medicines cited in Chinese Pharmacopoeia].
Zhongguo Zhong Yao Za Zhi: 2016, 41(16);2943-2952
[PubMed:28920330] [] [DOI] (P p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects