Uncaria rhynchophylla

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Nomenclature

Other Names:

Historical Use of Uncaria rhynchophylla

Uncaria rhynchophylla in Traditional Chinese Medicine

Background

Nengouteng ÄÛ¹³ÌÙ Shuangouteng Ë«¹³ÌÙ Chinese Name (pinyin): Gouteng

Chinese Name  :

Common Name  :Hooked Uncaria

Specific Name  : Ramulus uncariae cum uncis

Scientific Name:
Collection  : The drug is collected in autumn and winter, removed from leaf, cut into section and dried in the sun.

Description  : Cylindrical or subsquare, 2 - 3 cm long, 2 - 5 mm in diameter. Externally reddish brown to purplish red with fine longitudinal striations, glabrous or yellowish green to greyish brown. Sometimes with white dotted lenticels covered with yellowish brown pubescence. Most nodes of stem branch with two opposite downward curved hooks (sterile peduncles). Some only with a hook at one side and with raised scars at the other side, hooks relatively flattened or rounded, apex acute, base relatively broad, dotted scars of falling petiole and ring shaped stipule scars visible on the branch at the hook base. Texture hard and tenacious, fracture yellowish brown, bark fibrous, pith yellowish white or hollowed. Odourless, taste weak.

Identification  : Moisten 1 g of the powder with concentrated ammonia, add 30 ml of chloroform, extract for 30 minutes, filter and evaporate the filtrate to dryness. Dissolve the residue in 5 ml of hydrochloric acid solution (1Õ100). Filter into three test tubes. To the first tube add 1 - 2 drops of potassium iodobismuthate TS, a yellow precipitate is produced, to the second tube add 1 - 2 drops of mercuric potassium iodide TS, a white precipitate is produced. To the third tube add 1 - 2 drops of silicontungstic acid TS, a white precipitate is produced.

Processing  :

Action  : To remove heat, subdue hyperactivity of the liver, and arrest convulsions.

Indication  : headache, dizziness, convulsion, eclampsia, hypertension

Precautions  :

Dosage  : 3 to 12 g, to be added when the decoction is nearly done.

Storage  : Preserve in a dry place.

Synonymns for Uncaria rhynchophylla

Patent Medicines and Medicines with Multiple Ingredients that include Uncaria rhynchophylla

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Uncaria rhynchophylla in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Jian-Gang Zhang, Xiao-Yan Huang, Yun-Bao Ma, Ji-Jun Chen, Chang-An Geng
UFLC-PDA-MS/MS Profiling of Seven Uncaria Species Integrated with Melatonin/5-Hydroxytryptamine Receptors Agonistic Assay.
Nat Prod Bioprospect: 2020;
[PubMed:31933166] [WorldCat.org] [DOI] (P a)

Zhiqi Wen, Mingzhen He, Chunyan Peng, Yifei Rao, Junmao Li, Zhifeng Li, Lijun Du, Yan Li, Maofu Zhou, Ouyang Hui, Yulin Feng, Shilin Yang
##Title##
Front Pharmacol: 2019, 10;1425
[PubMed:31920639] [WorldCat.org] [DOI] (P e)

Yue Wang, Qing-Lan Guo, Ruo-Fei Li, Cheng-Bo Xu, Cheng-Gen Zhu, Jian-Gong Shi
Two folate-derived analogues from an aqueous decoction of Uncaria rhynchophylla.
Chin J Nat Med: 2019, 17(12);928-934
[PubMed:31882048] [WorldCat.org] [DOI] (I p)

Qiang Guo, Xiali Si, Yuntao Shi, Hongshuai Yang, Xinyu Liu, Hong Liang, Pengfei Tu, Qingying Zhang
##Title##
J. Nat. Prod.: 2019, 82(12);3288-3301
[PubMed:31804070] [WorldCat.org] [DOI] (I p)

Jia-Hao Liang, Zhi-Lin Luan, Xiang-Ge Tian, Wen-Yu Zhao, Ya-Li Wang, Cheng-Peng Sun, Xiao-Kui Huo, Sa Deng, Bao-Jing Zhang, Zhan-Jun Zhang, Xiao-Chi Ma
##Title##
J. Nat. Prod.: 2019, 82(12);3302-3310
[PubMed:31789520] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects