Uncaria hirsuta

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Nomenclature

Other Names:

Historical Use of Uncaria hirsuta

Uncaria hirsuta in Traditional Chinese Medicine

Background

Nengouteng ÄÛ¹³ÌÙ Shuangouteng Ë«¹³ÌÙ Chinese Name (pinyin): Gouteng

Chinese Name  :

Common Name  :Hooked Uncaria

Specific Name  : Ramulus uncariae cum uncis

Scientific Name:
Collection  : The drug is collected in autumn and winter, removed from leaf, cut into section and dried in the sun.

Description  : Cylindrical or subsquare, 2 - 3 cm long, 2 - 5 mm in diameter. Externally reddish brown to purplish red with fine longitudinal striations, glabrous or yellowish green to greyish brown. Sometimes with white dotted lenticels covered with yellowish brown pubescence. Most nodes of stem branch with two opposite downward curved hooks (sterile peduncles). Some only with a hook at one side and with raised scars at the other side, hooks relatively flattened or rounded, apex acute, base relatively broad, dotted scars of falling petiole and ring shaped stipule scars visible on the branch at the hook base. Texture hard and tenacious, fracture yellowish brown, bark fibrous, pith yellowish white or hollowed. Odourless, taste weak.

Identification  : Moisten 1 g of the powder with concentrated ammonia, add 30 ml of chloroform, extract for 30 minutes, filter and evaporate the filtrate to dryness. Dissolve the residue in 5 ml of hydrochloric acid solution (1Õ100). Filter into three test tubes. To the first tube add 1 - 2 drops of potassium iodobismuthate TS, a yellow precipitate is produced, to the second tube add 1 - 2 drops of mercuric potassium iodide TS, a white precipitate is produced. To the third tube add 1 - 2 drops of silicontungstic acid TS, a white precipitate is produced.

Processing  :

Action  : To remove heat, subdue hyperactivity of the liver, and arrest convulsions.

Indication  : headache, dizziness, convulsion, eclampsia, hypertension

Precautions  :

Dosage  : 3 to 12 g, to be added when the decoction is nearly done.

Storage  : Preserve in a dry place.

Synonymns for Uncaria hirsuta

Patent Medicines and Medicines with Multiple Ingredients that include Uncaria hirsuta

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Uncaria hirsuta in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Chien-Min Lin, Yi-Tzu Lin, Tai-Lin Lee, Zuha Imtiyaz, Wen-Chi Hou, Mei-Hsien Lee
In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland.
J Food Drug Anal: 2020, 28(1);147-158
[PubMed:31883603] [WorldCat.org] [DOI] (I p)

Huiqin Pan, Changliang Yao, Shuai Yao, Wenzhi Yang, Wanying Wu, Dean Guo
A metabolomics strategy for authentication of plant medicines with multiple botanical origins, a case study of Uncariae Rammulus Cum Uncis.
J Sep Sci: 2019;
[PubMed:31858716] [WorldCat.org] [DOI] (I a)

Jian-Gang Zhang, Ji-Jun Chen, Chang-An Geng
[Advances in indole alkaloids from traditional Chinese medicine of Uncariae Ramulus Cum Uncis documented in Chinese Pharmacopoeia].
Zhongguo Zhong Yao Za Zhi: 2019, 44(4);685-695
[PubMed:30989880] [WorldCat.org] [DOI] (P p)

Jinjun Hou, Ruihong Feng, Yibei Zhang, Huiqin Pan, Shuai Yao, Sumei Han, Zijin Feng, Luying Cai, Wanying Wu, De-An Guo
Characteristic Chromatogram: A Method of Discriminate and Quantitative Analysis for Quality Evaluation of Uncaria Stem with Hooks.
Planta Med.: 2018, 84(6-07);449-456
[PubMed:29216668] [WorldCat.org] [DOI] (I p)

Hui-Qin Pan, Wen-Zhi Yang, Dan Zhao, Cheng Luo, Chang-Liang Yao, Xiao-Jian Shi, Yi-Bei Zhang, Shi-You Li, Ying Bi, Zhen Wang, Shuai Yao, Wan-Ying Wu, De-An Guo
New monoterpenoid oxindole alkaloid derivatives from the stems of Uncaria hirsuta Havil. and their cytotoxicity and tandem mass spectrometric fragmentation.
Fitoterapia: 2017, 116;85-92
[PubMed:27889541] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects