Smilax glabra

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Other Names:

Historical Use of Smilax glabra

Smilax glabra in Traditional Chinese Medicine


Chinese Name (pinyin): Tufuling

Chinese Name  :

Common Name  :Smilax Glabra Rhizome

Specific Name  : Rhizoma smilacis glabrae

Scientific Name:
Collection  : The drug is collected in summer or autumn, removed from fibrous root, wash clean and dried or slice while fresh and dried.

Description  : Sub-cylindrical, slightly flattened or irregularly slat-shape and lump-shape with knob-like outgrowths and short branches. 5 - 22 cm long, 2 - 5 cm in diameter. Externally yellowish brown or greyish brown, uneven with stiff remains of fibrous roots and the tops of branches possessing rounded bud scars. Some outer bark irregularly fissured and exhibiting remains of scales. Texture hard. Slices oblong or irregular shape, 1 - 5 mm thick, edge irregular, transverse cut surface whitish to pale red brown, starchy, dotted vascular bundles and numerous small light, spots visible. Texture slightly tough, dusting on breaking, viscous and slippery when moistened. Odorless, taste slightly sweet and astringent.

Identification  : Powder: Pale brown, starch granules abundant, simple granules subspherical, polygonal or sub-square. 8 - 48 µm in diameter, hilum cleft, stellate, Y shape or pointed. Striations visible in large granules, compound granules consisting of 2 - 4 components. Raphides of calcium oxalate occuring in mucilage cells or scattered throughout, needle crystal 40 - 144 µm long, about 5 µm in diameter, stone cells sub-elliptical, sub-square or triangular, 25 - 128 µm in diameter with fine and close pit canals. Deep brown stone cells elongated, about 50 µm in diameter, walls heavily thickened on the three sides and thin on one side. Border pitted vessels and tracheids more frequent, most bordered pits elongated to scalariform.

Processing  : Eliminate foreign matter, soak the drug in water, wash clean, soften thoroughly, cut into thin slices and dry.

Action  : To remove damp, to counteract toxicity, and to improve the lobility of joints.

Indication  : dysuria with turbid discharge, leukorrhea, carbuncle, lymphadenitis, chronic eczema, contracture of limbs and muscle pain in syphilis with mercury poisoning

Precautions  :

Dosage  : 15 to 60 g.

Storage  : Preserve in a ventilated and dry place.

Synonymns for Smilax glabra

Patent Medicines and Medicines with Multiple Ingredients that include Smilax glabra

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Smilax glabra in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

SiddiqueAkber Ansari, Ahmed Bari, Riaz Ullah, Maghimaa Mathanmohun, Vishnu Priya Veeraraghavan, Zhongwei Sun
Gold nanoparticles synthesized with Smilax glabra rhizome modulates the anti-obesity parameters in high-fat diet and streptozotocin induced obese diabetes rat model.
J. Photochem. Photobiol. B, Biol.: 2019, 201;111643
[PubMed:31698218] [] [DOI] (I p)

Chuyang Lin, Su-Mei Cao, Ellen T Chang, Zhiwei Liu, Yonglin Cai, Zhe Zhang, Guomin Chen, Qi-Hong Huang, Shang-Hang Xie, Yu Zhang, Jingping Yun, Wei-Hua Jia, Yuming Zheng, Jian Liao, Yufeng Chen, Longde Lin, Qing Liu, Ingemar Ernberg, Guangwu Huang, Yi Zeng, Yi-Xin Zeng, Hans-Olov Adami, Weimin Ye
Chinese nonmedicinal herbal diet and risk of nasopharyngeal carcinoma: A population-based case-control study.
Cancer: 2019, 125(24);4462-4470
[PubMed:31544233] [] [DOI] (I p)

Liping Huang, Jiao Deng, Guangtong Chen, Meng Zhou, Jian Liang, Bo Yan, Jicheng Shu, Yonghong Liang, Huilian Huang
The anti-hyperuricemic effect of four astilbin stereoisomers in Smilax glabra on hyperuricemic mice.
J Ethnopharmacol: 2019, 238;111777
[PubMed:30851369] [] [DOI] (I p)

Lisha Dong, Jinqiu Zhu, Hongzhi Du, Heng Nong, Xichen He, Xiaoyu Chen
Evid Based Complement Alternat Med: 2018, 2018;6279328
[PubMed:30622606] [] [DOI] (P e)

Siwei Wang, Yuejuan Fang, Xinfen Yu, Lu Guo, Xiaoxi Zhang, Daozong Xia
The flavonoid-rich fraction from rhizomes of Smilax glabra Roxb. ameliorates renal oxidative stress and inflammation in uric acid nephropathy rats through promoting uric acid excretion.
Biomed. Pharmacother.: 2019, 111;162-168
[PubMed:30579255] [] [DOI] (I p)



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Pregnancy and Breastfeeding

Adverse Effects