Siegesbeckia pubescens

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P473 2.jpg
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Other Names:

Historical Use of Siegesbeckia pubescens

Siegesbeckia pubescens in Traditional Chinese Medicine


Chinese Name (pinyin): Xixiancao

Chinese Name  :

Common Name  :Siegesbeckia Herb

Specific Name  : Herba siegesbeckiae

Scientific Name:
Collection  : The drug is collected in summer and autumn before or at flowering stage, removed from foreign matter and dried in sun.

Description  : Stems subsquare, frequently branched, 30 - 110cm long, 0.3 - 1cm in diameter, externally greyish green, yellowish brown or purplish brown with longitudinal striations covered with grey pubscences, nodes distinct, slightly swollen, texture fragile, easily broken, fracture yellowish white or green pith broad, whitish, hollowed. Leaves opposite, Lamina frequently crumpled and rolled when whole, ovate greyish green, margin obtusely serrate, both surfaces with white pubescences, trinervous. Some showing yellow capitulum involcre, odour slight, taste slightly bitter.

Identification  :

Processing  : Eliminate foreign matter, wash, soften slightly, cut into sections and dry.Processed with wine: Clean sections and steam as describe under the method for steaming with wine (Appendix ll D) using 20kg of yellow rice wine per 100 kg of Herba Siegesbeckiae.

Action  : To relieve rheumatic conditions, to improve the motility of joints, and to counteract toxicity.

Indication  : rheumatic arthralgia with aching and weakness of the loins and knees, and numbness of the limbs; hemiplegia; rubella, sores with exudation

Precautions  :

Dosage  : 9 to 12 g.

Storage  : Preserve in a ventilated dry place.

Synonymns for Siegesbeckia pubescens

Patent Medicines and Medicines with Multiple Ingredients that include Siegesbeckia pubescens

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Siegesbeckia pubescens in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Jianbin Wang, Menghua Wu, Chun Gao, Hongzheng Fu
Semisynthesis of epoxy-pimarane diterpenoids from kirenol and their FXa inhibition activities.
Bioorg. Med. Chem.: 2019, 27(7);1320-1326
[PubMed:30792102] [] [DOI] (I p)

Qian Ru Zhang, Zhang Feng Zhong, Wei Sang, Wei Xiong, Hong Xun Tao, Guan Ding Zhao, Zhi Xin Li, Qiu Shuo Ma, Anfernee Kai Wing Tse, Yuan Jia Hu, Hua Yu, Yi Tao Wang
Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations.
J Ethnopharmacol: 2019, 228;200-209
[PubMed:30240786] [] [DOI] (I p)

Xiaoxu Gao, Jiangchun Wei, Lina Hong, Sanpeng Fan, Gaosheng Hu, Jingming Jia
Molecules: 2018, 23(9);
[PubMed:30200186] [] [DOI] (I e)

Wei Sang, Zhangfeng Zhong, Kegang Linghu, Wei Xiong, Anfernee Kai Wing Tse, Wai San Cheang, Hua Yu, Yitao Wang
Chin Med: 2018, 13;37
[PubMed:30002726] [] [DOI] (P e)

Hari Jang, Jin Woo Lee, Jun Gu Kim, Hye Ryoung Hong, Thi Phoung Linh Le, Jin Tae Hong, Youngsoo Kim, Mi Kyeong Lee, Bang Yeon Hwang
Nitric oxide inhibitory constituents from Siegesbeckia pubescens.
Bioorg. Chem.: 2018, 80;81-85
[PubMed:29890361] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects