Scrophularia ningpoensis

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Nomenclature

Other Names:

Historical Use of Scrophularia ningpoensis

Scrophularia ningpoensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Xuanshen

Chinese Name  :

Common Name  :Figwort Root

Specific Name  : Radix scrophulariae

Scientific Name:
Collection  : The drug is collected in winter when stem and leaves wither, removed from rhizome, bud, rootlet and soil, dried in the sun or baked to half dry. Piled up for 3 - 6 days, processed for several times until dried completely.

Description  : Subcylindrical, slightly thick at the middle part and slender at the lower part, sometimes slightly curved, 6 - 20 cm long, 1 - 3 cm in diameter. Externally greyish yellow or greyish brown with irregular longitudinal grooves, transverse lenticels, sparse transverse fissures and numerous rootlet scars. Texture compact, easily broken, fracture black, somewhat lustrous. Odour characteristic resembling caramel, taste sweetish and slightly bitter.

Identification  : Transverse section: Cortex relatively broad, stone cells scattered singly or 2 - 5 in groups, polygonal, subrounded or subsquare with thicker walls and distinct striations. Phloem rays much cleft, cambium in a ring. Xylem rays broad, also much cleft, vessels less, subpolygonal up to 113 µm in diameter, accompanied with wood fibres. Parenchymatous cells containing nucleus-like substance.Total ash: Not more than 5.0%

Processing  : Eliminate remains of rhizomes and foreign matter, wash clean, soften thoroughly, cut into slices and dry or soak briefly in water. Steam thoroughly, air dry briefly then cut into thin slices and dry completely.

Action  : To reduce heat from blood, to nourish yin, to quench fire, and to counteract toxicity.

Indication  : febrile diseases with impairment of yin manifested by deep red tongue and intense thirst, or with eruptions; constipation due to impairment of body fluid; phthisis with cough; conjunctivitis, sore throat, scrofula, diphtheria, boils and sores

Precautions  : Incompatible with Rhizoma et Radix Veratri.

Dosage  : 9 to 15 g.

Storage  : Preserve in a dry place, protected from mould and moth.

Synonymns for Scrophularia ningpoensis

Patent Medicines and Medicines with Multiple Ingredients that include Scrophularia ningpoensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Scrophularia ningpoensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Ke Wang, Yeliang Lou, Huang Xu, Xiaoming Zhong, Zhen Huang
Harpagide from Scrophularia protects rat cortical neurons from oxygen-glucose deprivation and reoxygenation-induced injury by decreasing endoplasmic reticulum stress.
J Ethnopharmacol: 2020;112614
[PubMed:32007630] [WorldCat.org] [DOI] (I a)

Junping Zheng, Man Chen, Cheng Ye, Xiongjie Sun, Nan Jiang, Xiaojuan Zou, Huabing Yang, Hongtao Liu
BuZangTongLuo decoction improved hindlimb ischemia by activating angiogenesis and regulating gut microbiota in diabetic mice.
J Ethnopharmacol: 2020, 248;112330
[PubMed:31654796] [WorldCat.org] [DOI] (I p)

Shuwei Ma, Xingyan Liu, Bin Cheng, Zhandong Jia, Hui Hua, Yang Xin
Chemical characterization of polysaccharides isolated from scrophularia ningpoensis and its protective effect on the cerebral ischemia/reperfusin injury in rat model.
Int. J. Biol. Macromol.: 2019, 139;955-966
[PubMed:31400420] [WorldCat.org] [DOI] (I p)

Hong-Bo Xu, Chun-Hui Gao, Xing-Hang Cai, Kang Yang, Yu Zhang, Juan-Juan Wang, Huai-Li Xu, Lu Zhang, Su-Yun Chen, Zhi-Shu Tang
[Preparation and quality standard of standard decoction of Scrophulariae Radix pieces].
Zhongguo Zhong Yao Za Zhi: 2019, 44(12);2493-2498
[PubMed:31359716] [WorldCat.org] [DOI] (P p)

Zhan-Yun Shen, Bo Zhu, Quan-Long Zhang, Lu-Ping Qin
[Isolation and identification of endophytic fungi producing harpagoside and harpagide from Scrophularia ningpoensis].
Zhongguo Zhong Yao Za Zhi: 2019, 44(10);2046-2050
[PubMed:31355559] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects