Sanguisorba officinalis

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Other Names:

Historical Use of Sanguisorba officinalis

Sanguisorba officinalis in Traditional Chinese Medicine


Diyutan µØÓÜÌ¿ Shengdiyu ÉúµØÓÜ Chinese Name (pinyin): Diyu

Chinese Name  :

Common Name  :Sanguisorba Root

Specific Name  : Radix sanguisorbae

Scientific Name:
Collection  : The drug is collected in spring during budding or autumn after withering, remove from rootlet, washed clean, dried or cut into slices while fresh an dried.

Description  : Irregular fusiform or cylindrical, slightly curved or twisted, 5 - 25 cm long, 0.5 - 2 cm in diameter. Externally greyish brown, brown or dark purple, rough with longitudinal wrinkles, transverse fissures and rootlet scars. Texture hard, fracture relatively even, bark with numerous yellowish white to yellowish brown. Wooly fibres, wood yellow or yellowish brown and approximately arranged radially. Slices irregularly rounded or elliptical. 2 - 5 mm thick, cut surface purplish red or brown. Odourless, taste slightly bitter and astringent.

Identification  : 1.To 2 g of the powder add 20 ml of ethanol, heat under reflux for about 10 minutes and filter. To the filtrate add ammonia TS dropwise to adjust to pH 8 - 9 and filter. Evaporate the filtrate to dryness. Dissolve the residue in 10 ml of water and filter. Evaporate 5 ml of the filtrate to dryness, add 1 ml of acetic andhydride and 2 drops of sulfuric acid, a red violet color is produced, becoming dark brown on standing.2.To a small quantity of the precipitate obtained under Identification (1), add 2 ml of water and 2 drops of ferric chloride TS. A bluish black colour is produced.Assay: Weigh accurately 10 g of the powder (through no. 3 sieve) Carry out the method for the determination of tanninoids (Appendix X B). It contains not less than 10.0% of tanninoids.

Processing  : Eliminate foreign matter, for the drug not sliced, wash clean, remove remains of stems, soften thoroughly, cut into thin slices and dry.(Carbonized): Stir fry the slices as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred while its inner part becomes brown.

Action  : To arrest bleeding by dispelling heat for blood, and to counteract toxicity and cure sores.

Indication  : hematochezia, hemorrhoidal bleeding, bloddy dysentery, abnormal uterine bleeding; scalds and burns; carbuncles, boils and sores

Precautions  : Incompatible with Rhizoma et Radix Veratri.

Dosage  : 9 to 15 g; for external use, appropriate quntity to be ground into powder nd applied topically.

Storage  : Preserve in a ventilated dry place, protected from moth.

Synonymns for Sanguisorba officinalis

Patent Medicines and Medicines with Multiple Ingredients that include Sanguisorba officinalis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Sanguisorba officinalis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Chongfei Bai, Yueshan Sun, Xianchao Pan, Jing Yang, Xiaoxuan Li, Anguo Wu, Dalian Qin, Shousong Cao, Wenjun Zou, Jianming Wu
Front Pharmacol: 2019, 10;1646
[PubMed:32047442] [] [DOI] (P e)

Rongshen Wang, Jinfeng Sun, Mei Jin, Chao Ye, Jiaming Wang, Long Jin, Ying Jie Ma, Wei Zhou, Gao Li
Nat. Prod. Res.: 2020;1-10
[PubMed:32037886] [] [DOI] (I a)

Lin-Jie Zhu, Lin Chen, Chong-Fei Bai, An-Guo Wu, Si-Cheng Liang, Fei-Hong Huang, Shou-Song Cao, Le Yang, Wen-Jun Zou, Jian-Ming Wu
A rapid and sensitive UHPLC-MS/MS method for the determination of ziyuglycoside I and its application in a preliminary pharmacokinetic study in healthy and leukopenic rats.
Biomed. Pharmacother.: 2020, 123;109756
[PubMed:31864212] [] [DOI] (I p)

Rongshen Wang, Jinfeng Sun, Mei Jin, Lan Jin, Yanqiu Qi, Lihua Cao, Wei Zhou, Gao Li
Nat. Prod. Res.: 2019;1-5
[PubMed:31795750] [] [DOI] (I a)

Magdalena Szejk-Arendt, Kamila Czubak-Prowizor, Anna Macieja, Tomasz Poplawski, Alicja Klaudia Olejnik, Izabela Pawlaczyk-Graja, Roman Gancarz, Halina Malgorzata Zbikowska
Polyphenolic-polysaccharide conjugates from medicinal plants of Rosaceae/Asteraceae family protect human lymphocytes but not myeloid leukemia K562 cells against radiation-induced death.
Int. J. Biol. Macromol.: 2019;
[PubMed:31765747] [] [DOI] (I a)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects