Rubia cordifolia

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Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Qiancao

Chinese Name  :

Common Name  :India Madder Root

Specific Name  : Herba rubiae

Scientific Name:
Collection  : The drug is collected in spring and summer, removed from soil and dry.

Description  : Rhizome nodular, marked with numerous fascilcled roots varying in thickness. Roots cylindrical, somewhat curved, 10 - 25 cm long, 0.2 - 1 cm in diameter, externally reddish brown or dark brown with fine longitudinal wrinkles and a few rootlet scars. The place where the outer bark has exfoliated appearing yellowish red. Texture fragile, easily broken, fracture even, bark narrow and purplish red, wood broad, pale yellowish red, exhibiting numerous pores of vessels. Odourless, taste bitterish with an irritating sensation to the tongue when chewed for a long time.

Identification  : 1.Transverse section of the root: Cork cells 6 - 12 layered containing brown contents. Parenchymatous cells in cortex sometimes containing reddish brown granules. Cells in phloem relatively small. Cambium ring less distinct. The majority of root occupied by wood, completely lignified, xylem rays indistinct. Parenchymatous cells containing raphides of calcium oxalate.2.Shake 0.2 g of the powder with 5 ml of ether for several minutes and filter. To the filtrate add 1 ml of sodium hydroxide TS, shake and allow to stand. The water layer shows a red color. The ether layer is colorless. Examine the ether layer under an ultra violet light (365 nm) a sky blue fluorescence is shown.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.

Processing  : Eliminate foreign matter, wash, soften thoroughly, cut into thick slices or section and dry.Carbonized: Stir fry slices or sections of Radix Rubiae as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred.

Action  : To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge.

Indication  : spitting of blood, epistaxis, abnormal uterine bleeding, traumatic bleeding; amenorrhea with blood stasis; arthralgia, traumatic swelling and pain

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place.

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Qiancaotan Üç²ÝÌ¿ Chinese Name (pinyin): Qiancaogen

Chinese Name  :

Common Name  :Rubia Root

Specific Name  : Radix Rubiae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-10g

Storage  :

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Qiancao

Chinese Name  :

Common Name  :India Madder Root

Specific Name  : Herba rubiae

Scientific Name:
Collection  : The drug is collected in spring and summer, removed from soil and dry.

Description  : Rhizome nodular, marked with numerous fascilcled roots varying in thickness. Roots cylindrical, somewhat curved, 10 - 25 cm long, 0.2 - 1 cm in diameter, externally reddish brown or dark brown with fine longitudinal wrinkles and a few rootlet scars. The place where the outer bark has exfoliated appearing yellowish red. Texture fragile, easily broken, fracture even, bark narrow and purplish red, wood broad, pale yellowish red, exhibiting numerous pores of vessels. Odourless, taste bitterish with an irritating sensation to the tongue when chewed for a long time.

Identification  : 1.Transverse section of the root: Cork cells 6 - 12 layered containing brown contents. Parenchymatous cells in cortex sometimes containing reddish brown granules. Cells in phloem relatively small. Cambium ring less distinct. The majority of root occupied by wood, completely lignified, xylem rays indistinct. Parenchymatous cells containing raphides of calcium oxalate.2.Shake 0.2 g of the powder with 5 ml of ether for several minutes and filter. To the filtrate add 1 ml of sodium hydroxide TS, shake and allow to stand. The water layer shows a red color. The ether layer is colorless. Examine the ether layer under an ultra violet light (365 nm) a sky blue fluorescence is shown.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.

Processing  : Eliminate foreign matter, wash, soften thoroughly, cut into thick slices or section and dry.Carbonized: Stir fry slices or sections of Radix Rubiae as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred.

Action  : To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge.

Indication  : spitting of blood, epistaxis, abnormal uterine bleeding, traumatic bleeding; amenorrhea with blood stasis; arthralgia, traumatic swelling and pain

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place.

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Qiancaotan Üç²ÝÌ¿ Chinese Name (pinyin): Qiancaogen

Chinese Name  :

Common Name  :Rubia Root

Specific Name  : Radix Rubiae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-10g

Storage  :

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Qiancao

Chinese Name  :

Common Name  :India Madder Root

Specific Name  : Herba rubiae

Scientific Name:
Collection  : The drug is collected in spring and summer, removed from soil and dry.

Description  : Rhizome nodular, marked with numerous fascilcled roots varying in thickness. Roots cylindrical, somewhat curved, 10 - 25 cm long, 0.2 - 1 cm in diameter, externally reddish brown or dark brown with fine longitudinal wrinkles and a few rootlet scars. The place where the outer bark has exfoliated appearing yellowish red. Texture fragile, easily broken, fracture even, bark narrow and purplish red, wood broad, pale yellowish red, exhibiting numerous pores of vessels. Odourless, taste bitterish with an irritating sensation to the tongue when chewed for a long time.

Identification  : 1.Transverse section of the root: Cork cells 6 - 12 layered containing brown contents. Parenchymatous cells in cortex sometimes containing reddish brown granules. Cells in phloem relatively small. Cambium ring less distinct. The majority of root occupied by wood, completely lignified, xylem rays indistinct. Parenchymatous cells containing raphides of calcium oxalate.2.Shake 0.2 g of the powder with 5 ml of ether for several minutes and filter. To the filtrate add 1 ml of sodium hydroxide TS, shake and allow to stand. The water layer shows a red color. The ether layer is colorless. Examine the ether layer under an ultra violet light (365 nm) a sky blue fluorescence is shown.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.

Processing  : Eliminate foreign matter, wash, soften thoroughly, cut into thick slices or section and dry.Carbonized: Stir fry slices or sections of Radix Rubiae as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred.

Action  : To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge.

Indication  : spitting of blood, epistaxis, abnormal uterine bleeding, traumatic bleeding; amenorrhea with blood stasis; arthralgia, traumatic swelling and pain

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place.

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Qiancaotan Üç²ÝÌ¿ Chinese Name (pinyin): Qiancaogen

Chinese Name  :

Common Name  :Rubia Root

Specific Name  : Radix Rubiae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-10g

Storage  :

Synonymns for Rubia cordifolia

Patent Medicines and Medicines with Multiple Ingredients that include Rubia cordifolia

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Rubia cordifolia in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Syeda Fatima, Nazia Aslam, Sofia Khalid, Kalim Ullah, Khizar Abbas, Shahzad Hussain, Syed Sajid Hussain Shah, Zia-Ur-Rahman Qureshi, Mughal Qayum, Muhammad Hassham Hassan Bin Asad
##Title##
Biomed Res Int: 2021, 2021;6618349
[PubMed:33816618] [WorldCat.org] [DOI] (I e)

Alfonso Barrós-Loscertales, Sergio Elías Hernández, Yaqiong Xiao, José Luis González-Mora, Katya Rubia
Resting State Functional Connectivity Associated With Sahaja Yoga Meditation.
Front Hum Neurosci: 2021, 15;614882
[PubMed:33796013] [WorldCat.org] [DOI] (P e)

Cristina Pascual-Izquierdo, Julio Del Rio-Garma, Javier de la Rubia, Aurora Viejo, Eva Mingot, Joan Cid, Xavier Solanich, Jesús Fernández-Sojo, Jesús Martín-Sánchez, Luis Hernández, José María García-Gala, Nieves Alonso, Victoria González, Ana Oliva, Inés Gómez-Seguí, Rosa Goterris, Luisa Guerra, Faustino García-Candel, Marta Fernández-Docampo, María Luisa Antelo, Ángel Salgado-Barreira, Ramón Salinas, Spanish Apheresis Group (GEA) and Spanish Thrombotic Thrombocytopenic Purpura Registry (REPTT)
Incidence, diagnosis, and outcome of immune-mediated thrombotic thrombocytopenic purpura: A nationwide survey by the Spanish registry of thrombotic thrombocytopenic purpura.
J Clin Apher: 2021;
[PubMed:33780553] [WorldCat.org] [DOI] (I a)

Alessandro Mengozzi, Georgios Georgiopoulos, Marco Falcone, Giusy Tiseo, Nicola Riccardo Pugliese, Meletios A Dimopoulos, Lorenzo Ghiadoni, Greta Barbieri, Francesco Forfori, Laura Carrozzi, Massimo Santini, Fabio Monzani, Salvatore De Marco, Francesco Menichetti, Agostino Virdis, Stefano Masi, Pisa Covid Study Group
The relationship between cardiac injury, inflammation and coagulation in predicting COVID-19 outcome.
Sci Rep: 2021, 11(1);6515
[PubMed:33753759] [WorldCat.org] [DOI] (I e)

Merel C Postema, Martine Hoogman, Sara Ambrosino, Philip Asherson, Tobias Banaschewski, Cibele E Bandeira, Alexandr Baranov, Claiton H D Bau, Sarah Baumeister, Ramona Baur-Streubel, Mark A Bellgrove, Joseph Biederman, Janita Bralten, Daniel Brandeis, Silvia Brem, Jan K Buitelaar, Geraldo F Busatto, Francisco X Castellanos, Mara Cercignani, Tiffany M Chaim-Avancini, Kaylita C Chantiluke, Anastasia Christakou, David Coghill, Annette Conzelmann, Ana I Cubillo, Renata B Cupertino, Patrick de Zeeuw, Alysa E Doyle, Sarah Durston, Eric A Earl, Jeffery N Epstein, Thomas Ethofer, Damien A Fair, Andreas J Fallgatter, Stephen V Faraone, Thomas Frodl, Matt C Gabel, Tinatin Gogberashvili, Eugenio H Grevet, Jan Haavik, Neil A Harrison, Catharina A Hartman, Dirk J Heslenfeld, Pieter J Hoekstra, Sarah Hohmann, Marie F Høvik, Terry L Jernigan, Bernd Kardatzki, Georgii Karkashadze, Clare Kelly, Gregor Kohls, Kerstin Konrad, Jonna Kuntsi, Luisa Lazaro, Sara Lera-Miguel, Klaus-Peter Lesch, Mario R Louza, Astri J Lundervold, Charles B Malpas, Paulo Mattos, Hazel McCarthy, Leyla Namazova-Baranova, Rosa Nicolau, Joel T Nigg, Stephanie E Novotny, Eileen Oberwelland Weiss, Ruth L O'Gorman Tuura, Jaap Oosterlaan, Bob Oranje, Yannis Paloyelis, Paul Pauli, Felipe A Picon, Kerstin J Plessen, J Antoni Ramos-Quiroga, Andreas Reif, Liesbeth Reneman, Pedro G P Rosa, Katya Rubia, Anouk Schrantee, Lizanne J S Schweren, Jochen Seitz, Philip Shaw, Tim J Silk, Norbert Skokauskas, Juan C Soliva Vila, Michael C Stevens, Gustavo Sudre, Leanne Tamm, Fernanda Tovar-Moll, Theo G M van Erp, Alasdair Vance, Oscar Vilarroya, Yolanda Vives-Gilabert, Georg G von Polier, Susanne Walitza, Yuliya N Yoncheva, Marcus V Zanetti, Georg C Ziegler, David C Glahn, Neda Jahanshad, Sarah E Medland, ENIGMA ADHD Working Group, Paul M Thompson, Simon E Fisher, Barbara Franke, Clyde Francks
Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets.
J Child Psychol Psychiatry: 2021;
[PubMed:33748971] [WorldCat.org] [DOI] (I a)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects