Rubia cordifolia

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P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Qiancao

Chinese Name  :

Common Name  :India Madder Root

Specific Name  : Herba rubiae

Scientific Name:
Collection  : The drug is collected in spring and summer, removed from soil and dry.

Description  : Rhizome nodular, marked with numerous fascilcled roots varying in thickness. Roots cylindrical, somewhat curved, 10 - 25 cm long, 0.2 - 1 cm in diameter, externally reddish brown or dark brown with fine longitudinal wrinkles and a few rootlet scars. The place where the outer bark has exfoliated appearing yellowish red. Texture fragile, easily broken, fracture even, bark narrow and purplish red, wood broad, pale yellowish red, exhibiting numerous pores of vessels. Odourless, taste bitterish with an irritating sensation to the tongue when chewed for a long time.

Identification  : 1.Transverse section of the root: Cork cells 6 - 12 layered containing brown contents. Parenchymatous cells in cortex sometimes containing reddish brown granules. Cells in phloem relatively small. Cambium ring less distinct. The majority of root occupied by wood, completely lignified, xylem rays indistinct. Parenchymatous cells containing raphides of calcium oxalate.2.Shake 0.2 g of the powder with 5 ml of ether for several minutes and filter. To the filtrate add 1 ml of sodium hydroxide TS, shake and allow to stand. The water layer shows a red color. The ether layer is colorless. Examine the ether layer under an ultra violet light (365 nm) a sky blue fluorescence is shown.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.

Processing  : Eliminate foreign matter, wash, soften thoroughly, cut into thick slices or section and dry.Carbonized: Stir fry slices or sections of Radix Rubiae as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred.

Action  : To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge.

Indication  : spitting of blood, epistaxis, abnormal uterine bleeding, traumatic bleeding; amenorrhea with blood stasis; arthralgia, traumatic swelling and pain

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place.

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Qiancaotan Üç²ÝÌ¿ Chinese Name (pinyin): Qiancaogen

Chinese Name  :

Common Name  :Rubia Root

Specific Name  : Radix Rubiae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-10g

Storage  :

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Qiancao

Chinese Name  :

Common Name  :India Madder Root

Specific Name  : Herba rubiae

Scientific Name:
Collection  : The drug is collected in spring and summer, removed from soil and dry.

Description  : Rhizome nodular, marked with numerous fascilcled roots varying in thickness. Roots cylindrical, somewhat curved, 10 - 25 cm long, 0.2 - 1 cm in diameter, externally reddish brown or dark brown with fine longitudinal wrinkles and a few rootlet scars. The place where the outer bark has exfoliated appearing yellowish red. Texture fragile, easily broken, fracture even, bark narrow and purplish red, wood broad, pale yellowish red, exhibiting numerous pores of vessels. Odourless, taste bitterish with an irritating sensation to the tongue when chewed for a long time.

Identification  : 1.Transverse section of the root: Cork cells 6 - 12 layered containing brown contents. Parenchymatous cells in cortex sometimes containing reddish brown granules. Cells in phloem relatively small. Cambium ring less distinct. The majority of root occupied by wood, completely lignified, xylem rays indistinct. Parenchymatous cells containing raphides of calcium oxalate.2.Shake 0.2 g of the powder with 5 ml of ether for several minutes and filter. To the filtrate add 1 ml of sodium hydroxide TS, shake and allow to stand. The water layer shows a red color. The ether layer is colorless. Examine the ether layer under an ultra violet light (365 nm) a sky blue fluorescence is shown.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.

Processing  : Eliminate foreign matter, wash, soften thoroughly, cut into thick slices or section and dry.Carbonized: Stir fry slices or sections of Radix Rubiae as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred.

Action  : To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge.

Indication  : spitting of blood, epistaxis, abnormal uterine bleeding, traumatic bleeding; amenorrhea with blood stasis; arthralgia, traumatic swelling and pain

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place.

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Qiancaotan Üç²ÝÌ¿ Chinese Name (pinyin): Qiancaogen

Chinese Name  :

Common Name  :Rubia Root

Specific Name  : Radix Rubiae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-10g

Storage  :

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Qiancao

Chinese Name  :

Common Name  :India Madder Root

Specific Name  : Herba rubiae

Scientific Name:
Collection  : The drug is collected in spring and summer, removed from soil and dry.

Description  : Rhizome nodular, marked with numerous fascilcled roots varying in thickness. Roots cylindrical, somewhat curved, 10 - 25 cm long, 0.2 - 1 cm in diameter, externally reddish brown or dark brown with fine longitudinal wrinkles and a few rootlet scars. The place where the outer bark has exfoliated appearing yellowish red. Texture fragile, easily broken, fracture even, bark narrow and purplish red, wood broad, pale yellowish red, exhibiting numerous pores of vessels. Odourless, taste bitterish with an irritating sensation to the tongue when chewed for a long time.

Identification  : 1.Transverse section of the root: Cork cells 6 - 12 layered containing brown contents. Parenchymatous cells in cortex sometimes containing reddish brown granules. Cells in phloem relatively small. Cambium ring less distinct. The majority of root occupied by wood, completely lignified, xylem rays indistinct. Parenchymatous cells containing raphides of calcium oxalate.2.Shake 0.2 g of the powder with 5 ml of ether for several minutes and filter. To the filtrate add 1 ml of sodium hydroxide TS, shake and allow to stand. The water layer shows a red color. The ether layer is colorless. Examine the ether layer under an ultra violet light (365 nm) a sky blue fluorescence is shown.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.

Processing  : Eliminate foreign matter, wash, soften thoroughly, cut into thick slices or section and dry.Carbonized: Stir fry slices or sections of Radix Rubiae as described under the method for carbonizing by stir frying (Appendix ll D) until the outer part is charred.

Action  : To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge.

Indication  : spitting of blood, epistaxis, abnormal uterine bleeding, traumatic bleeding; amenorrhea with blood stasis; arthralgia, traumatic swelling and pain

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place.

P308 1.jpg
Tcm275.jpg

Nomenclature

Other Names:

Historical Use of Rubia cordifolia

Rubia cordifolia in Traditional Chinese Medicine

Background

Qiancaotan Üç²ÝÌ¿ Chinese Name (pinyin): Qiancaogen

Chinese Name  :

Common Name  :Rubia Root

Specific Name  : Radix Rubiae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-10g

Storage  :

Synonymns for Rubia cordifolia

Patent Medicines and Medicines with Multiple Ingredients that include Rubia cordifolia

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Rubia cordifolia in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

R Rodríguez-Vázquez, A Mato, M López-Pedrouso, D Franco, M A Sentandreu, C Zapata
Measuring quantitative proteomic distance between Spanish beef breeds.
Food Chem: 2020, 315;126293
[PubMed:32028200] [WorldCat.org] [DOI] (I p)

Kidong Kang, Khong Trong Quan, Hee Sun Byun, So-Ra Lee, Xuezhe Piao, Eunjin Ju, Kyeong Ah Park, Kyung-Cheol Sohn, Han-Ming Shen, MinKyun Na, Gang Min Hur
3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ.
FASEB J.: 2020;
[PubMed:32027418] [WorldCat.org] [DOI] (I a)

Shanyong Yi, Qianwen Lin, Xuejia Zhang, Jing Wang, Yuanyuan Miao, Ninghua Tan
##Title##
Biomed Res Int: 2020, 2020;5824841
[PubMed:31998793] [WorldCat.org] [DOI] (I e)

Ivo Marx, Katya Rubia, Olaf Reis, Valdas Noreika
A short note on the reliability of perceptual timing tasks as commonly used in research on developmental disorders.
Eur Child Adolesc Psychiatry: 2020;
[PubMed:31955249] [WorldCat.org] [DOI] (I a)

Li Ma, Pei Hu, Junfang Zhang, Wugeng Cui, Xin Zhao
Purpurin exerted antidepressant-like effects on behavior and stress axis reactivity: evidence of serotonergic engagement.
Psychopharmacology (Berl.): 2020;
[PubMed:31900524] [WorldCat.org] [DOI] (I a)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects