Rehmannia glutinosa

From Epilepsy Naturapedia
Jump to: navigation, search
Tcm132.jpg
Tcm p52 000c.jpg
P156 1.jpg
Tcm7.jpg

Nomenclature

Other Names:

Historical Use of Rehmannia glutinosa

Rehmannia glutinosa in Traditional Chinese Medicine

Background

Ganshengdi ¸ÉÉúµØ Shengdi ÉúµØ Shengditan ÉúµØÌ¿ Xiandihuang Ï浯Ȯ Chinese Name (pinyin): Shengdihuang

Chinese Name  :

Common Name  :Rehmannia Root

Specific Name  : Radix Rehmanniae

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 10-30g

Storage  :

Tcm132.jpg
Tcm p52 000c.jpg
P156 1.jpg
Tcm7.jpg

Nomenclature

Other Names:

Historical Use of Rehmannia glutinosa

Rehmannia glutinosa in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Dihuang

Chinese Name  :

Common Name  :Rehmannia root

Specific Name  : Radix rehmanniae

Scientific Name:
Collection  : The drug is collected in autumn, removed from root stock, rootlet and soil, use either in fresh state or baked to almost dry. The former is known as "Xian Dihuang" (Fresh Rehmanniae Root) and the latter is known as "Sheng Dihuang" (Unprocessed Rehmannia Root)

Description  : Xian Dihuang: Fusiform or slat shaped, 8 - 24 cm long, 2 - 9 cm in diameter, the outer bark thin, externally pale reddish yellow with curved longitudinal wrinkles, bue scars, elongated transverse lenticels and irregular scars. Texture fleshy, easily broken, yellowish white, orange red oil dots scattered in bark, fracture yellowish white with vessels arranged radial in wood, odour slight, taste slightly sweet and bitterish.Sheng Dihuang: Mostly in irregular masses or oblong, swollen in the center, slightly tapering at both ends. 6 - 12 cm long, 3 - 6 cm in diameter, some small slit shaped, slightly compressed or twisted. Externally brownish black or brownish greyish with irregular transverse wavy lines. Texture heavy, soft and tenacious, uneasily broken, fracture brownish black or jet black, lustrous, viscous. Odourless, taste slightly sweet.

Identification  : 1.Transverse section: Cork consisting of several layers of cells. In cortex parenchymatous cells loosely arranged, scattered with more secretory cells containing orange yellow oil droplets, stone cells occasionally found. Phloem relatively broad, secretory cells less. Xylem rays broad, vesserls sparse arranged radially. Powder of Sheng Dihuang: Dark brown, cork cells brownish, subrectangular in lateral view, regularly arranged. Parenchymatous cells subrounded, containing subrounded nuclei. Secretory cells mostly similar to ordinary parenchymatous cells in shape, containing orange or orange red oil droplets. Bordered pitted and reticulate vessels up to about 92 µm in diameter.2.To 2 g of the powder add 20 ml of methanol, heat under reflux on a water bath for 1 hour, cool, filter, distill the filtrate to recover methanol, until 5 ml of filtrate is remained. Use the filtrate as the test solution. Dissolve catalpol CRS in methanol to produce a solution containing 0.5 mg per ml used as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G as the coating substance and a mixture of chloroform-methanol-water (70:30:5) as the mobile phase. Apply separately to the plate 5 µl of each of the above two solutions. After developing and removal of the plate, dry it in the air. Spray with anysaldehyde TS, heat at 105ºC for 5 minutes. A spot in the chromatogram obtained from the test solution correspond in colour and position to the spot in the chromatogram obtained from the reference solution.Total ash: Not more than 6.0% (Appendix lX K).Acid insoluble ash: Not more than 2.0% (Appendix lX K).Water soluble extractives: Carry out the method for determination of extractives-cold maceration method (Appendix X A) not less than 65.0%.

Processing  : Eliminate foreign matter, wash clean, cover to soften, cut into thick slices and dry.

Action  : Fresh Radix Rehmanniae: To remove heat and promote production of body fluid, to reduce heat in blood, and to arrest bleeding.

Indication  : fresh: impairment of yin in febrile diseases marked by deep red tongue and thirst; skin eruption and maculation; spitting of blood, epistaxis; sore throat unprepared: febrile diseases with deep red tongue and thirst; dficiency of yin with internal heat; consumptive fever; diabetes caused by internal heat; spitting of blood, epistaxis; skin eruption and maculation

Precautions  :

Dosage  : Fresh Radix Rehmanniae: 12 to 30 g. Radix Rehmanniae (unprocessed); 9 to 15 g.

Storage  : Embed Fresh Radix Rehmannia Root in sand and protect from freezing; unprocessed Rehmannia Root is preserved in a ventilated dry plce, protected from mould and moth.

Tcm132.jpg
Tcm p52 000c.jpg
P156 1.jpg
Tcm7.jpg

Nomenclature

Other Names:

Historical Use of Rehmannia glutinosa

Rehmannia glutinosa in Traditional Chinese Medicine

Background

Shudihuang ÊìµØ»Æ Chinese Name (pinyin): Shudi

Chinese Name  :

Common Name  :Prepared Rehmannia Root

Specific Name  : Radix Rehmanniae Paeparata

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 15-30g

Storage  :

Tcm132.jpg
Tcm p52 000c.jpg
P156 1.jpg
Tcm7.jpg

Nomenclature

Other Names:

Historical Use of Rehmannia glutinosa

Rehmannia glutinosa in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Shudihuang

Chinese Name  :

Common Name  :Rehmannia Root (processed)

Specific Name  : Radix rehumanniae preparata

Scientific Name:
Collection  : The drug is the processed Radix Rehmanniae.Procedure1.Stew the clean Radix Rehmanniae as described under the method for stewing with wine (Appendix ll D) until the wine is absorbed entirely, take out, dry in the sun until the muscilage in bark is slightly dried. Cut into thick slices or pieces and dry thoroughly. To each 100 kg of Radix Rehmanniae add 30 - 50 kg of yellow rice wine.2.Steam the clean Radix Rehmanniae as described under the method for steaming (Appendix ll D) until it becomes blackish and shiny. Take out, dry in the sun to be 80% dried, cut into thick slices or pieces and dry thoroughly.

Description  : Occurring in regular slices and pieces, broken lumps, varying in size and thickness. Externally jet-black, lustrous, more sticky. Texture soft and flexible, uneasily broken, jet-black, lustrous. Odourless, taste sweet.

Identification  : To 1 g of the powder add 10 ml of ethanol, macerate for 24 hors, filter and use the filtrate as the test solution. Dissolve 5-(hydroxy methyl) furfural CRS in ethanol to produce a solution containing o.5 mg per ml as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel GF254 as the coating substance and petroleum ether (60 - 90ºC).-ethyl acetate (1:1) as the mobile phase. Apply separately 10 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air. Examine under the ultra violet light (254 nm), the spot in the chromatogram obtained with the test solution correspond in position and colour to the spot in the chromatogram obtained with the reference solution.Extractives: Comply with the test for Radix Rehmannia.

Processing  :

Action  : To nourish yin and replenish blood, reinforce the essence of life and marrow.

Indication  : dficiency of liver and kidney yin marked by aching and limpness of the lins and knees, consumptive fever, night sweating and seminal emission; diabetes caused by internal heat; anemia; palpitation; menstrual disorders, abnormal uterine bleeding; dizziness, tinnitus; premature greying of beard and hair

Precautions  :

Dosage  : 9 to 15 g.

Storage  : Preserve in a ventilated nd dry place.

Synonymns for Rehmannia glutinosa

Patent Medicines and Medicines with Multiple Ingredients that include Rehmannia glutinosa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Rehmannia glutinosa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Zhuo Xu, Xin-Xin Dai, Qing-Yang Zhang, Shu-Lan Su, Hui Yan, Yue Zhu, Er-Xin Shang, Da-Wei Qian, Jin-Ao Duan
Protective effects and mechanisms of Rehmannia glutinosa leaves total glycoside on early kidney injury in db/db mice.
Biomed. Pharmacother.: 2020, 125;109926
[PubMed:32028239] [WorldCat.org] [DOI] (I a)

Hong-Ying Li, Jiang-Ji Fang, Hua-Dan Shen, Xue-Qiong Zhang, Xiao-Ping Ding, Jun-Feng Liu
"Quantity-effect" research strategy for comparison of antioxidant activity and quality of Rehmanniae Radix and Rehmannia Radix Praeparata by on-line HPLC-UV-ABTS assay.
BMC Complement Med Ther: 2020, 20(1);16
[PubMed:32020888] [WorldCat.org] [DOI] (I e)

Yan Chen, Qingpu Liu, Zengfu Shan, Wangyang Mi, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng, Weisheng Feng
Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy.
Front Pharmacol: 2019, 10;1477
[PubMed:31920663] [WorldCat.org] [DOI] (P e)

Xin Wang, Cuiting Wu, Ming Xu, Cong Cheng, Youping Liu, Xin Di
Optimisation for simultaneous determination of iridoid glycosides and oligosaccharides in Radix Rehmannia by microwave assisted extraction and HILIC-UHPLC-TQ-MS/MS.
Phytochem Anal: 2020;
[PubMed:31899590] [WorldCat.org] [DOI] (I a)

Subrat Kumar Bhattamisra, Kah Heng Yap, Vikram Rao, Hira Choudhury
Multiple Biological Effects of an Iridoid Glucoside, Catalpol and Its Underlying Molecular Mechanisms.
Biomolecules: 2019, 10(1);
[PubMed:31878316] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects