Quinine

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Quinine is a non-scientific common name that may refer to a number of plant species and varieties.

Nomenclature

Other Names:

Historical Use of Quinine

Quinine in Traditional Chinese Medicine

Description

Historical Use of Quinine in Western Medicine

Quote Paraph: "On bromide of ammonium (•) i. three times a day) [IN THE ORIGINAL TEXT, THE "•)" WAS REPRESENTED AS ONE SYMBOL, A SEMICIRCLE OPENED TO THE LEFT WHICH INSCRIBED A DOT.], the fits ceased for several months, and the lad discontinued attendance, but returned in consequence of a recurrence. On the same treatment, and on bromide and belladonna, the attacks continued very frequent, and although they were lessened by bromide and digitalis, they did not cease until oxide of zinc was substituted for the digitalis, the dose of bromide remaining the same. The attacks then at once ceased, and when he had had no attack for eleven months, quinine was substituted for the bromide and zinc. He has now taken this for three months without any relapse."
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Primary Source: Gowers, WR. Epilepsy and other chronic convulsive diseases. New York. William Wood & Company. 1885. p. 227.

Background

Synonymns for Quinine

Patent Medicines and Medicines with Multiple Ingredients that include Quinine

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Quinine in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Sara Eyal
The Fever Tree: from Malaria to Neurological Diseases.
Toxins (Basel): 2018, 10(12);
[PubMed:30477182] [WorldCat.org] [DOI] (I e)

Xiao Ran, Jing Xiang, Pan-Pan Song, Li Jiang, Ben-Ke Liu, Yue Hu
Effects of gap junctions blockers on fast ripples and connexin in rat hippocampi after status epilepticus.
Epilepsy Res.: 2018, 146;28-35
[PubMed:30056318] [WorldCat.org] [DOI] (I p)

Javier Franco-Pérez, Joaquín Manjarrez-Marmolejo, Cesar Rodríguez-Balderas, Nelly Castro, Paola Ballesteros-Zebadua
Quinine and carbenoxolone enhance the anticonvulsant activity of some classical antiepileptic drugs.
Neurol. Res.: 2018, 40(1);26-33
[PubMed:28988516] [WorldCat.org] [DOI] (I p)

Azeem Danish, Vigneshwaran Namasivayam, Anke C Schiedel, Christa E Müller
Interaction of Approved Drugs with Synaptic Vesicle Protein 2A.
Arch. Pharm. (Weinheim): 2017, 350(3-4);
[PubMed:28220535] [WorldCat.org] [DOI] (I p)

Zahra Faridkia, Parichehr Yaghmaei, Marjan Nassiri-Asl
Protective Effect of Quinine on Chemical Kindling and Passive Avoidance Test in Rats.
Iran Red Crescent Med J: 2016, 18(9);e25490
[PubMed:28144451] [WorldCat.org] [DOI] (P e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects