Pulsatilla chinensis
Contents
Nomenclature
Other Names:
Historical Use of Pulsatilla chinensis
Pulsatilla chinensis in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Baitouweng
Chinese Name :
Common Name :Pulsatilla Root
Specific Name : Radix pulsatillae
Scientific Name:
Collection : The drug is collected in spring and autumn, removed from soil and dried.
Description : Subcylindrical or conical, slightly tortous, 6 - 20 cm long, 0.5 - 2 cm in diameter. Externally yellowish brown or brown, irregualrly and longitudinally wrinkled or furrowed, bark easily exfoliated, the exposed wood yellow, some exhibiting reticulated fissures and cracks, usually with decayed depressed holes near root stock. Root stock slightly swollen, white tomentose, some showing sheath like pedicel bases. Texture hard and fracture yellowish white or pale yellowish brown in bark and pale yellow in wood. Odour slight, taste slightly bitter and astringent.
Identification : 1.Powder: Greyish brown, phloem fibres fusiform or spindle shaped, 100 - 390 µm long, 16 - 42 µm in diameter with lignified walls. Non-glandular hairs unicellular, 13 - 33 µm in diameter, the base slightly inflated, the walls mostly lignified. Some showing spiral striations. Bordered pitted, reticulate and spiral vessels, 10 - 72 µm in diameter.2.To 4 g of the powder, add 20 ml of ethanol, heat under reflux for 1 hour and filter. Concentrate the filtrate to about 6 ml on a water bath and cool. Add appropriate quantity of acetone, a precipitate is produced. Filter and transfer about 5 mg of precipitate to a test tube immediately. Add 1 ml of acetic anhydride to dissolve, add 1 ml of sulfuric acid along the tube wall, a red to red violet colour form at the junction of the two liquids.
Processing : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.
Action : To remove toxic heat nd relieve bloody dysentery.
Indication : dysentery due to amebiasis; pudendal itching with excessive leukorrhea
Precautions :
Dosage : 9 to 15 g.
Storage : Preserve in a ventilated dry place.
Synonymns for Pulsatilla chinensis
Patent Medicines and Medicines with Multiple Ingredients that include Pulsatilla chinensis
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Pulsatilla chinensis in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Zeping Fan, Yaru Cui, Lanying Chen, Peng Liu, Wenbin Duan
23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling.
Cancer Immunol Immunother: 2024, 73(5);83
[PubMed:38554148]
[WorldCat.org]
[DOI]
(I e)
Junfeng Tan, Zengguang Zhang, Dan Zheng, Yu Mu, Bixuan Cao, Junwei Yang, Li Han, Xueshi Huang
Structure-activity relationship and biofilm formation-related gene targets of oleanolic acid-type saponins from Pulsatilla chinensis against Candida albicans.
Bioorg Chem: 2024, 146;107311
[PubMed:38547720]
[WorldCat.org]
[DOI]
(I p)
Mingyue Xiao, Ronghua Luo, Qinghua Liang, Honglv Jiang, Yanli Liu, Guoqiang Xu, Hongwei Gao, Yongtang Zheng, Qiongming Xu, Shilin Yang
##Title##
Chin Herb Med: 2024, 16(1);106-112
[PubMed:38375049]
[WorldCat.org]
[DOI]
(I e)
Che Bian, Yan-Ping Xing, He-Fei Xue, Wen-Juan Hou, Yan-Yun Yang, Liang Xu, Ting-Guo Kang
##Title##
Mitochondrial DNA B Resour: 2024, 9(2);233-236
[PubMed:38313466]
[WorldCat.org]
[DOI]
(I e)
Mingzhen Xue, Cheng Yang, Wensi Huang, Yifei He, Chen Yang, Yaru Xue, Yuandong Zheng, Xingxing Diao, Xiachang Wang
Pharmacokinetics and metabolite identification of 23-hydroxybetulinic acid in rats by using liquid chromatography-mass spectrometry method.
J Chromatogr B Analyt Technol Biomed Life Sci: 2024, 1234;124016
[PubMed:38266610]
[WorldCat.org]
[DOI]
(I p)
