Pulsatilla chinensis

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Nomenclature

Other Names:

Historical Use of Pulsatilla chinensis

Pulsatilla chinensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Baitouweng

Chinese Name  :

Common Name  :Pulsatilla Root

Specific Name  : Radix pulsatillae

Scientific Name:
Collection  : The drug is collected in spring and autumn, removed from soil and dried.

Description  : Subcylindrical or conical, slightly tortous, 6 - 20 cm long, 0.5 - 2 cm in diameter. Externally yellowish brown or brown, irregualrly and longitudinally wrinkled or furrowed, bark easily exfoliated, the exposed wood yellow, some exhibiting reticulated fissures and cracks, usually with decayed depressed holes near root stock. Root stock slightly swollen, white tomentose, some showing sheath like pedicel bases. Texture hard and fracture yellowish white or pale yellowish brown in bark and pale yellow in wood. Odour slight, taste slightly bitter and astringent.

Identification  : 1.Powder: Greyish brown, phloem fibres fusiform or spindle shaped, 100 - 390 µm long, 16 - 42 µm in diameter with lignified walls. Non-glandular hairs unicellular, 13 - 33 µm in diameter, the base slightly inflated, the walls mostly lignified. Some showing spiral striations. Bordered pitted, reticulate and spiral vessels, 10 - 72 µm in diameter.2.To 4 g of the powder, add 20 ml of ethanol, heat under reflux for 1 hour and filter. Concentrate the filtrate to about 6 ml on a water bath and cool. Add appropriate quantity of acetone, a precipitate is produced. Filter and transfer about 5 mg of precipitate to a test tube immediately. Add 1 ml of acetic anhydride to dissolve, add 1 ml of sulfuric acid along the tube wall, a red to red violet colour form at the junction of the two liquids.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To remove toxic heat nd relieve bloody dysentery.

Indication  : dysentery due to amebiasis; pudendal itching with excessive leukorrhea

Precautions  :

Dosage  : 9 to 15 g.

Storage  : Preserve in a ventilated dry place.

Synonymns for Pulsatilla chinensis

Patent Medicines and Medicines with Multiple Ingredients that include Pulsatilla chinensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Pulsatilla chinensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

You Jin Nam, Eun Young Lee, Eun-Ju Choi, Sangjin Kang, Jinwan Kim, Yong-Soo Choi, Dong Hyun Kim, Ji Hae An, Inbo Han, Sunghou Lee, Min Ho Lee, Young Ho Kim, Ji Hyung Chung
CRH receptor antagonists from Pulsatilla chinensis prevent CRH-induced premature catagen transition in human hair follicles.
J Cosmet Dermatol: 2020;
[PubMed:32056369] [WorldCat.org] [DOI] (I a)

Ying Zhou, Jinhua Wen, Guangji Wang
Identification of cytochrome P450 isoenzymes involved in the metabolism of 23-hydroxybetulinic acid in human liver microsomes.
Pharm Biol: 2020, 58(1);60-63
[PubMed:31868554] [WorldCat.org] [DOI] (I p)

Tingting Zhang, Yanping Xing, Liang Xu, Guihua Bao, Zhilai Zhan, Yanyun Yang, Jiahao Wang, Shengnan Li, Dachuan Zhang, Tingguo Kang
##Title##
Chin Med: 2019, 14;53
[PubMed:31798674] [WorldCat.org] [DOI] (P e)

Naixin Kang, Wenhua Shen, Yong Zhang, Zhetong Su, Shilin Yang, Yanli Liu, Qiongming Xu
Anti-inflammatory and immune-modulatory properties of anemoside B4 isolated from Pulsatilla chinensis in vivo.
Phytomedicine: 2019, 64;152934
[PubMed:31454651] [WorldCat.org] [DOI] (I p)

Shuyi Xue, Yu Zhou, Jin Zhang, Zhuo Xiang, Yang Liu, Ting Miao, Guoxin Liu, Bangguo Liu, Xu Liu, Lixia Shen, Zhe Zhang, Mingchun Li, Qing Miao
Anemoside B4 exerts anti-cancer effect by inducing apoptosis and autophagy through inhibiton of PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
Am J Transl Res: 2019, 11(4);2580-2589
[PubMed:31105864] [WorldCat.org] (P e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects