Pseudostellaria heterophylla

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Other Names:

Historical Use of Pseudostellaria heterophylla

Pseudostellaria heterophylla in Traditional Chinese Medicine


Haiershen º¢¶ù²Î Tongzishen ͯ×ӲΠChinese Name (pinyin): Taizishen

Chinese Name  :

Common Name  :Pseudostellaria Root

Specific Name  : Radix pseudostellariae

Scientific Name:
Collection  : The drug is collected in autumn when the stem and leaves are mostly withered, wash clean, removed from rootlet. Either treated with boiling water for a moment and dried in the sun or dried in the sun directly.

Description  : Slenderly fusiform or slat shaped, slightly curved, 3 - 10 cm long, 2 - 6 mm in diameter. Root stock marked with stem scars. Externally yellowish white, relatively smooth but slightly wrinkled longitudinally with rootlet scars at a dent. Texture hard and fragile, fracture even, yellowish white and horny or whitish and starchy. Odour slight, taste sweetish.

Identification  : 1.Transverse section: Cork consisting of 2 - 4 rows of subsquare cells. Cortex thin only consisting of several rows of parenchymatous cells, elongated tangentially. Phloem narrow with broad rays. Cambium in a ring. The majority of root occupied by xylem, vessels sparse and arranged radially, primary xylem occurring triarch to tetriarch. Parenchymatous cells packed with starch granules and clusters of calcium oxalate.2.Macerate warmly 1 g of the powder in 10 ml of methanol, shake for 30 minutes, filter. Use filtrate as the test solution. Prepare a solution of Radix Pseudostillaria reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G containing sodium carboxymethyl cellulose as the coating substance and n-butanol-glacial acetic acid-water (4:1:1) as the mobile phase. Apply separately 1 µl of each of the two solutions to the plate. After developing in a chamber pre-equilibrated with mobile phase for 15 minutes and removal of the plate, dry it in the air, spray with 0.2% ninhydrin ethanol solution. Heat at 105ºC until the colour spots appear clearly. A spot in the chromatogram obtained from the test solution corresponds in colour and position to the spot in the chromatogram obtained from the reference drug solution.

Processing  :

Action  : To replenish qi and invigorate the spleen function, and to promote fluid secretion and moisten the lung.

Indication  : hypofunction of the spleen with lassitude and anorexia; debility and deficiency of qi and yin marked by spontaneous sweating and thirst during convalescence dry cough due to dryness of the lung

Precautions  :

Dosage  : 9 to 30 g.

Storage  : Preserve in a ventilated dry place, protected from moisture and moth.

Synonymns for Pseudostellaria heterophylla

Patent Medicines and Medicines with Multiple Ingredients that include Pseudostellaria heterophylla

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Pseudostellaria heterophylla in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Wei Zheng, Tao Zhou, Jun Li, Weike Jiang, Jinqiang Zhang, Chenghong Xiao, Dequn Wei, Changgui Yang, Rong Xu, Anhui Gong, Chen Zhang, Yan Bi
Front Plant Sci: 2019, 10;1259
[PubMed:31749814] [] [DOI] (P e)

Linkun Wu, Bo Yang, Manlin Li, Jun Chen, Zhigang Xiao, Hongmiao Wu, Qingyu Tong, Xiaomian Luo, Wenxiong Lin
Plant Dis.: 2020, 104(1);25-34
[PubMed:31726014] [] [DOI] (P p)

Qian Yang, Muchen Huang, Xixi Cai, Lee Jia, Shaoyun Wang
Investigation on activation in RAW264.7 macrophage cells and protection in cyclophosphamide-treated mice of Pseudostellaria heterophylla protein hydrolysate.
Food Chem. Toxicol.: 2019, 134;110816
[PubMed:31518602] [] [DOI] (I p)

Dejun Hu, Bangxing Han, Cunwu Chen, Naifu Chen, Baojie Zhu, Jing Zhao, Shaoping Li
Determination of seven oligosaccharides and sucrose in Pseudostellaria heterophylla by pressurized liquid extraction and ultra-high performance liquid chromatography with charged aerosol detector and tandem mass spectrometry.
J Chromatogr A: 2020, 1609;460441
[PubMed:31439440] [] [DOI] (I p)

Qian Yang, Xixi Cai, Muchen Huang, Lee Jia, Shaoyun Wang
Food Funct: 2019, 10(6);3466-3476
[PubMed:31140514] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects