Potentilla chinensis

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Nomenclature

Other Names:

Historical Use of Potentilla chinensis

Potentilla chinensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Weilingcai

Chinese Name  :

Common Name  :Chinese Cinquefoil

Specific Name  : Herba potentillae chinensis

Scientific Name:
Collection  : The drug is collected in spring before the sprouting of the stem, remove from soil and dried in the sun.

Description  : roots cylindrical or subconical, slightly twisted, sometimes branched, 5 - 17cm long, 0.5 - 1cm diameter, externally dark brown or dark purplish red striated longitudinally, the coarse outer bark easily exfoliate, roots stocks slightly swollen, texture hard, easily broken, bark in fracture thin, dark brown, easily separated from wood rays arranged radially. Basal leaves, odd pinnate, petioled, leaflets narrowly long elliptical, margin pinnatipartite, the lower surface and petiole densely covered with greyish white, pubescences. Odour slight taste astringent and slightly bitter.

Identification  : 1.Powder: Greyish brown, non-glandular, hairs numerous, unicellular, straight or curve some twisted into a loose mass, slender, 7 - 37µm in diameter up to about 4000µm long with thickened walls. Mesophyll cells containing clusters of calcium oxalate, 6 - 65µm in diameter and small prisms occasionally. Wood fibres long fusiform, 7 - 14µm in diameter, walls slightly thickened and distinctly pitted. Cork cells subpolygonal or flattened rectangular containing yellowish-brown contents.2.To 1g of the powder add 10 ml of petroleum ether (90 - 120ºC), macerate warmly for 3 hours., filter, evaporate the residue of petroleum ether to dryness, add 10ml of ethanol to the residue, filter, concentrate the filtrate to about 1ml and use it as the test solution. Prepare a solution of Herba Potentillae Chinensis reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G conatining sodium carboxymethyl cellulose as the coating substance and a mixture of toluene-ethyl-formate-formic acid (5:4:1) as the mobile phase. Apply separately to the plate 6µl of each of the above two solutions. After developing and removal of the plate, dry it in the air, spray with a mixture of 2% ferric chloride solution and potassium ferricyanide TS mixed in equal portions. A blue spot in the chromatogram obtained from the test solution correspond in colour and position to spot in the chromatogram obtained from the reference solution.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into sections and dry in the sun.

Action  : To remove toxic heat and reduce heat in blood, and to relieve dysentery.

Indication  : dysentery with bloody stools, chronic dysentery; hemorrhoidal bleeding; carbuncles and sores

Precautions  :

Dosage  : 9 to 15 g; for external use, appropriate quantity of the fresh herb to be decocted for washing or pounded into paste for topical application.

Storage  : Preserve in a ventilated dry place.

Synonymns for Potentilla chinensis

Patent Medicines and Medicines with Multiple Ingredients that include Potentilla chinensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Potentilla chinensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Dandan Wang, Lingling Lao, Xiaohong Pang, Qian Qiao, Lijun Pang, Zhongwen Feng, Facheng Bai, Xuemei Sun, Xing Lin, Jinbin Wei
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Int. Immunopharmacol.: 2018, 65;256-267
[PubMed:30340105] [WorldCat.org] [DOI] (I p)

Chang Zhang, Yue Jiang, Jia Liu, Meina Jin, Nan Qin, Ying Chen, Wenyan Niu, Hongquan Duan
AMPK/AS160 mediates tiliroside derivatives-stimulated GLUT4 translocation in muscle cells.
Drug Des Devel Ther: 2018, 12;1581-1587
[PubMed:29910604] [WorldCat.org] [DOI] (I e)

Guang Wan, Jin-Gang Tao, Guo-Dong Wang, Shen-Peng Liu, Hong-Xing Zhao, Qiu-Dong Liang
In vitro antitumor activity of the ethyl acetate extract of Potentilla chinensis in osteosarcoma cancer cells.
Mol Med Rep: 2016, 14(4);3634-40
[PubMed:27573158] [WorldCat.org] [DOI] (I p)

Songlin Shi, Zongshan Li, Hao Wang, Georg von Arx, Yihe Lü, Xing Wu, Xiaochun Wang, Guohua Liu, Bojie Fu
Roots of forbs sense climate fluctuations in the semi-arid Loess Plateau: Herb-chronology based analysis.
Sci Rep: 2016, 6;28435
[PubMed:27323906] [WorldCat.org] [DOI] (I e)

Yi Sun, Ying Wang, Bi-lin Tan, Yan-ru Deng
[Comparison of Six Flavonoid Components of Closely-Related Plants Agrimonia pilosa,Potentilla chinensis and Potentilla discolor].
Zhong Yao Cai: 2016, 39(5);991-5
[PubMed:30132635] [WorldCat.org] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects