- 1 Nomenclature
- 2 Historical Use of Polygonatum odoratum
- 3 Background
- 4 Pharmaceutical Information
- 5 Evidence or the Use of Polygonatum odoratum in the Treatment of Epilepesy
- 6 Safety
Historical Use of Polygonatum odoratum
Polygonatum odoratum in Traditional Chinese Medicine
Chinese Name (pinyin): Yuzhu
Chinese Name :
Common Name :Fragrant Solomonseal Rhizome
Specific Name : Rhizoma Polygonati Odorati
Collection : The drug is collected in autumn, removed from the fibrous root, washed clean , dried in the sun to soften, repeatedly rubbed and dried in the air until the drug is devoid of hard core and dried in the sun thoroughly. Or after washing steamed thoroughly or rubbed to translucent after thoroughly steaming and dried in the sun.
Description : Long cylindrical, slightly compressed, few branched, 4 - 18 cm long, 0.3 - 1.6 cm in diameter. Externally yellowish white or yellowish brown, translucent with longitudinal wrinkles and slightly raised annulations exhibiting white rounded dotted fibrous root scars and a disk like stem scar. Texture hard fragile or slightly soft, easily broken, fracture horny or granular. Odour slight, taste sweetish and viscous in chewing.
Identification : Transverse section: Epidermal cells oblate or compressed rectangular, outer walls slightly thickened cutinized. Numerous mucilage cells scattered throughout parenchyma, 80 - 140 µm in diameter, containing raphides of calcium oxalate. Collateral bundles, a few amphivasal bundles scattered.Assay: Standard preparation: Weigh accurately 60 mg of anhydrous glucose CRS dried previously to constant weight at 105ºC (Appendix lX G) in a 100 ml volumetric flask, dissolve in water and dilute to volume (containing 0.6mg of anhydrous glucose per ml).Preparation of standard curve: Measure accurately 0.0,11.0, 1.5, 2.0, 2.5, 3.0 ml of the reference solution in 50 ml volumetric flask, dilute with water to volume and mix well. Transfer 2 ml accurately measured of each of the resulting solution to stoppered tube respectively, add 1 ml of 4% phenol solution, mix well, add 0.7ml of sulfuric acid quickly, shake, keep in a 40ºC water bath for 30 minutes then moved to the ice bath for 5 minutes. Carry out the method for spectrophotometry (Appendix V B). Measure the absorbance at 490nm, taking the first tube as a blank and plot the standard curve using absorbance as ordinate and concentration as abcissa.Procedure: Weigh accurately 1 g of the coarse powder in a round bottom flask, add 100 ml of water, heat under reflux for 1 hour, filter with absorbent cotton. Repeat the extraction as above once, combine the filtrate, concentrate and transfer to a 100ml volumetric flask, dilute with water to volume, mix well. Measure accurately 2 ml of the solution. Add 10 ml of ethanol, stir and centrifuge, discard the supernatants and dissolve the precipitate in water to a 50ml volumetric flask and dilute to volume. Measure 2 ml of the resulting solution, carry out the procedure as describe under preparation of standard curve, beginning at the word "add 1 ml of 4% phenol?", measure the absorbance, read out the weight of the polysaccharide of Rhizoma Polygonati Odorati (µg) in the test solution from the standard curve and calculate. It contains not less than 6.0% of Polysaccharide calculated as glucose (C6H12O6) on the dried basis.
Processing : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices or sections and dry.
Indication : impairment of yin of the lung and the stomach with dry cough, dryness of the throat and thirst; diabetes caused by internal heat
Dosage : 10-30g
Synonymns for Polygonatum odoratum
Patent Medicines and Medicines with Multiple Ingredients that include Polygonatum odoratum
Evidence or the Use of Polygonatum odoratum in the Treatment of Epilepesy
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
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