Polygonatum odoratum

From Epilepsy Naturapedia
Jump to: navigation, search
P103 2.jpg
Tcm77.jpg

Nomenclature

Other Names:

Historical Use of Polygonatum odoratum

Polygonatum odoratum in Traditional Chinese Medicine

Background

Weirui ÝÚÞ¨ Chinese Name (pinyin): Yuzhu

Chinese Name  :

Common Name  :Fragrant Solomonseal Rhizome

Specific Name  : Rhizoma Polygonati Odorati

Scientific Name:
Collection  : The drug is collected in autumn, removed from the fibrous root, washed clean , dried in the sun to soften, repeatedly rubbed and dried in the air until the drug is devoid of hard core and dried in the sun thoroughly. Or after washing steamed thoroughly or rubbed to translucent after thoroughly steaming and dried in the sun.

Description  : Long cylindrical, slightly compressed, few branched, 4 - 18 cm long, 0.3 - 1.6 cm in diameter. Externally yellowish white or yellowish brown, translucent with longitudinal wrinkles and slightly raised annulations exhibiting white rounded dotted fibrous root scars and a disk like stem scar. Texture hard fragile or slightly soft, easily broken, fracture horny or granular. Odour slight, taste sweetish and viscous in chewing.

Identification  : Transverse section: Epidermal cells oblate or compressed rectangular, outer walls slightly thickened cutinized. Numerous mucilage cells scattered throughout parenchyma, 80 - 140 µm in diameter, containing raphides of calcium oxalate. Collateral bundles, a few amphivasal bundles scattered.Assay: Standard preparation: Weigh accurately 60 mg of anhydrous glucose CRS dried previously to constant weight at 105ºC (Appendix lX G) in a 100 ml volumetric flask, dissolve in water and dilute to volume (containing 0.6mg of anhydrous glucose per ml).Preparation of standard curve: Measure accurately 0.0,11.0, 1.5, 2.0, 2.5, 3.0 ml of the reference solution in 50 ml volumetric flask, dilute with water to volume and mix well. Transfer 2 ml accurately measured of each of the resulting solution to stoppered tube respectively, add 1 ml of 4% phenol solution, mix well, add 0.7ml of sulfuric acid quickly, shake, keep in a 40ºC water bath for 30 minutes then moved to the ice bath for 5 minutes. Carry out the method for spectrophotometry (Appendix V B). Measure the absorbance at 490nm, taking the first tube as a blank and plot the standard curve using absorbance as ordinate and concentration as abcissa.Procedure: Weigh accurately 1 g of the coarse powder in a round bottom flask, add 100 ml of water, heat under reflux for 1 hour, filter with absorbent cotton. Repeat the extraction as above once, combine the filtrate, concentrate and transfer to a 100ml volumetric flask, dilute with water to volume, mix well. Measure accurately 2 ml of the solution. Add 10 ml of ethanol, stir and centrifuge, discard the supernatants and dissolve the precipitate in water to a 50ml volumetric flask and dilute to volume. Measure 2 ml of the resulting solution, carry out the procedure as describe under preparation of standard curve, beginning at the word "add 1 ml of 4% phenol?", measure the absorbance, read out the weight of the polysaccharide of Rhizoma Polygonati Odorati (µg) in the test solution from the standard curve and calculate. It contains not less than 6.0% of Polysaccharide calculated as glucose (C6H12O6) on the dried basis.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices or sections and dry.

Action  :

Indication  : impairment of yin of the lung and the stomach with dry cough, dryness of the throat and thirst; diabetes caused by internal heat

Precautions  :

Dosage  : 10-30g

Storage  :

Synonymns for Polygonatum odoratum

Patent Medicines and Medicines with Multiple Ingredients that include Polygonatum odoratum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Polygonatum odoratum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Shengxiang Zhang, Yuanyuan Shi, Luqi Huang, Chenkai Wang, Derui Zhao, Kelong Ma, Jiawen Wu, Daiyin Peng
Comparative transcriptomic analysis of rhizomes, stems, and leaves of Polygonatum odoratum (Mill.) Druce reveals candidate genes associated with polysaccharide synthesis.
Gene: 2020, 744;144626
[PubMed:32224272] [WorldCat.org] [DOI] (I a)

Ping Zhao, Xia Li, Ying Wang, Lanyi Yan, Lanping Guo, Luqi Huang, Wenyuan Gao
Characterisation and saccharide mapping of polysaccharides from four common Polygonatum spp.
Carbohydr Polym: 2020, 233;115836
[PubMed:32059888] [WorldCat.org] [DOI] (I p)

Ping Zhao, Huifang Zhou, Chengcheng Zhao, Xia Li, Ying Wang, Ying Wang, Luqi Huang, Wenyuan Gao
Purification, characterization and immunomodulatory activity of fructans from Polygonatum odoratum and P. cyrtonema.
Carbohydr Polym: 2019, 214;44-52
[PubMed:30926006] [WorldCat.org] [DOI] (I p)

Yan Wang, Yanquan Fei, Lirui Liu, Yunhua Xiao, Yilin Pang, Jinhe Kang, Zheng Wang
Polygonatum odoratum Polysaccharides Modulate Gut Microbiota and Mitigate Experimentally Induced Obesity in Rats.
Int J Mol Sci: 2018, 19(11);
[PubMed:30428630] [WorldCat.org] [DOI] (I e)

Deli Ning, Ming Jin, Tao Xv, Jikai Sun, Min Li
##Title##
Oncol Lett: 2018, 16(3);3545-3554
[PubMed:30127960] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects