Polygala sibirica
Contents
Nomenclature
Other Names:
Historical Use of Polygala sibirica
Polygala sibirica in Traditional Chinese Medicine
Background
Chaoyuanzhi ³´Ô¶Ö¾
Yuanzhirou Ô¶Ö¾Èâ
Chinese Name (pinyin): Yuanzhi
Chinese Name :
Common Name :Polygala Root
Specific Name : Radix polygalae
Scientific Name:
Collection : The drug is collected in spring and autumn, removed from rootlet and soil and dried in the sun.
Description : Cylindrical somewhat curved. 3 - 15 cm long, 3 - 8 mm in diameter. Externally greyish yellow to greyish brown with dense and dented transverse wrinkles, longitudinal wrinkles and fissures, old roots with denser and deeply dented transverse wrinkles, somewhat nodular. Texture hard and fragile, uneasily broken, fracture brownish yellow in bark. Yellowish white in wood. Bark easily separating from wood. Odour slight, taste bitter and slightly pungent with an irritative sensation in the throat on chewing.
Identification : 1.Transverse section: Cork of 10 or more rows of cells. Cortex of 20 or more rows of parenchymatous cells, tangentially cleft. Phloem relatively broad, usually radial clefted. Cambium in a ring. Xylem well develop, all lignified, rays 1 -3 rows of cells wide. Parenchymatous cells mostly containing fixed oil drops, some containing clusters and prisms of calcium oxalate.2.Place about 0.5g of the powder into a stoppered test tube. Add 10 ml of hot water. Keep the temperature for 10 minutes and shake vigorously for 1 minute. A persistent foam is produced, persisting for at least 10 minutes.Total ash: Not more than 6.0%
Processing : Eliminate foreign matter, wash briefly, soften thoroughly, cut into sections and dry.Radix Polygalae (prepared): Decoct Radix Glycyrrhizae with a quantity of water, remove the residue. Add clean Radix Polygalae, decoct gently until the liquid is exhausted and dry , using 6 kg of Radix Glycyrrhizae for 100 kg of Radix Polygalae.
Action : To induce sedation and benefit the mentality, to promote expectoration, and to cause subsidence of swelling.
Indication : insomnia, dream-disturbed sleep, forgetfulness, palpitation, trance; cough with sputum difficult to expectorate; boils and sores, swelling and pain in the breast
Precautions :
Dosage : 3 to 9 g.
Storage : Preserve in a ventilated dry place.
Synonymns for Polygala sibirica
Patent Medicines and Medicines with Multiple Ingredients that include Polygala sibirica
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Polygala sibirica in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Yuanyuan Li, Huimin Zheng, Qiuhui Yao, Yongbo Ma, Lei Wang, Qian Liu, Yuhong Liu
Preparation, structural characteristics and pharmacological activity of polysaccharides from Polygala tenuifolia: A review.
Carbohydr Res: 2024, 539;109117
[PubMed:38626569]
[WorldCat.org]
[DOI]
(I a)
Guoqiang Guan, Houkang Cao, Zixuan Tang, Kefeng Zhang, Mingli Zhong, Rui Lv, Weimin Wan, Fengyue Guo, Yongwang Wang, Ya Gao
Mechanistic studies on the alleviation of ANIT-induced cholestatic liver injury by Polygala fallax Hemsl. polysaccharides.
J Ethnopharmacol: 2024, 328;118108
[PubMed:38574780]
[WorldCat.org]
[DOI]
(I p)
Heng Kong, Yuan-Yuan Han, Gai-Ling Yang, Kang Li, Lu Yu, Xun-Kai Xie, Guang-Yuan Xia, Peng-Ju Wei, Wan-Rong Zhang, Chu-Hua Li
Tenuifolin improves learning and memory by regulating long-term potentiation and dendritic structure of hippocampal CA1 area in healthy female mice but not male mice.
Behav Brain Res: 2024, 466;114974
[PubMed:38554850]
[WorldCat.org]
[DOI]
(I a)
Kaize Shen, Yu Xiong, Yanfang Liu, Xingwang Fan, Rui Zhu, Zumao Hu, Congying Li, Yan Hua
##Title##
J Fungi (Basel): 2024, 10(3);
[PubMed:38535204]
[WorldCat.org]
[DOI]
(I e)
Guocui Liang, Chengxia Gao, Liwei Zhang, Huizhi Du
##Title##
Nat Prod Res: 2024;1-5
[PubMed:38529756]
[WorldCat.org]
[DOI]
(I a)
