Polygala sibirica

From Epilepsy Naturapedia
Jump to: navigation, search
P199 1.jpg
P198 2.jpg


Other Names:

Historical Use of Polygala sibirica

Polygala sibirica in Traditional Chinese Medicine


Chaoyuanzhi ³´Ô¶Ö¾ Yuanzhirou Ô¶Ö¾Èâ Chinese Name (pinyin): Yuanzhi

Chinese Name  :

Common Name  :Polygala Root

Specific Name  : Radix polygalae

Scientific Name:
Collection  : The drug is collected in spring and autumn, removed from rootlet and soil and dried in the sun.

Description  : Cylindrical somewhat curved. 3 - 15 cm long, 3 - 8 mm in diameter. Externally greyish yellow to greyish brown with dense and dented transverse wrinkles, longitudinal wrinkles and fissures, old roots with denser and deeply dented transverse wrinkles, somewhat nodular. Texture hard and fragile, uneasily broken, fracture brownish yellow in bark. Yellowish white in wood. Bark easily separating from wood. Odour slight, taste bitter and slightly pungent with an irritative sensation in the throat on chewing.

Identification  : 1.Transverse section: Cork of 10 or more rows of cells. Cortex of 20 or more rows of parenchymatous cells, tangentially cleft. Phloem relatively broad, usually radial clefted. Cambium in a ring. Xylem well develop, all lignified, rays 1 -3 rows of cells wide. Parenchymatous cells mostly containing fixed oil drops, some containing clusters and prisms of calcium oxalate.2.Place about 0.5g of the powder into a stoppered test tube. Add 10 ml of hot water. Keep the temperature for 10 minutes and shake vigorously for 1 minute. A persistent foam is produced, persisting for at least 10 minutes.Total ash: Not more than 6.0%

Processing  : Eliminate foreign matter, wash briefly, soften thoroughly, cut into sections and dry.Radix Polygalae (prepared): Decoct Radix Glycyrrhizae with a quantity of water, remove the residue. Add clean Radix Polygalae, decoct gently until the liquid is exhausted and dry , using 6 kg of Radix Glycyrrhizae for 100 kg of Radix Polygalae.

Action  : To induce sedation and benefit the mentality, to promote expectoration, and to cause subsidence of swelling.

Indication  : insomnia, dream-disturbed sleep, forgetfulness, palpitation, trance; cough with sputum difficult to expectorate; boils and sores, swelling and pain in the breast

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a ventilated dry place.

Synonymns for Polygala sibirica

Patent Medicines and Medicines with Multiple Ingredients that include Polygala sibirica

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Polygala sibirica in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Shasha Yu, Haiyu Ji, Xiaodan Dong, Anjun Liu, Juan Yu
FAS/FAS-L-mediated apoptosis and autophagy of SPC-A-1 cells induced by water-soluble polysaccharide from Polygala tenuifolia.
Int. J. Biol. Macromol.: 2020, 150;449-458
[PubMed:32027895] [WorldCat.org] [DOI] (I a)

Shiwei Chao, Qin Xu, Shaoning Dong, Min Guo, Xusheng Liu, Xueren Cheng
J. Int. Med. Res.: 2020, 48(1);300060519894124
[PubMed:32000547] [WorldCat.org] [DOI] (I p)

Aline Maire du Poset, Andrea Zitolo, Fabrice Cousin, Ali Assifaoui, Adrien Lerbret
Evidence for an egg-box-like structure in iron(ii)-polygalacturonate hydrogels: a combined EXAFS and molecular dynamics simulation study.
Phys Chem Chem Phys: 2020, 22(5);2963-2977
[PubMed:31956870] [WorldCat.org] [DOI] (I p)

Yuji Tokumoto, Kayo Hashimoto, Takashi Soyano, Seishiro Aoki, Wataru Iwasaki, Mai Fukuhara, Tomomi Nakagawa, Kazuhiko Saeki, Jun Yokoyama, Hironori Fujita, Masayoshi Kawaguchi
Assessment of Polygala paniculata (Polygalaceae) characteristics for evolutionary studies of legume-rhizobia symbiosis.
J. Plant Res.: 2020, 133(1);109-122
[PubMed:31828682] [WorldCat.org] [DOI] (I p)

Georgios Schoretsanitis, Jose de Leon, Chin B Eap, John M Kane, Michael Paulzen
Clinically Significant Drug-Drug Interactions with Agents for Attention-Deficit/Hyperactivity Disorder.
CNS Drugs: 2019, 33(12);1201-1222
[PubMed:31776871] [WorldCat.org] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects