Podophyllum emodi

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P52 1.jpg

Nomenclature

Other Names:

Historical Use of Podophyllum emodi

Podophyllum emodi in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Xiaoyelian

Chinese Name  :

Common Name  :Common Sinopodophyllum Fruit

Specific Name  : Fructus podophylli

Scientific Name:
Collection  : The drug is collected in autumn when ripe, remove from foreign matter and dried.

Description  : Ellipsoidal or subspheroidal, mostly flattened, 3 - 5.5cm long, 2 - 4cm in diameter. Externally purplish red or purplish brown, shrunken, seeds sometimes visible. Apex slightly acute, fruit stalk yellowish brown, mostly fallen. Sarcocarp adhering to pericarp, forming a thin slice, easily broken, containing numerous seeds. Seeds subovoid, about 4mm long, externally reddish-purple with fine furrows and small protrusion at one end. Texture hard, kernel white, oily. Odor slight, taste sour, sweet and astringent, seeds bitter.

Identification  :

Processing  :

Action  : To regulate menstruation and promote the flow of blood.

Indication  : amenorrhea due to blood stasis, difficult labor, missed labor, placenta retention

Precautions  :

Dosage  : 3 to 9 g; usually made into pills or powder.

Storage  : Preserve in a dry place.

P52 1.jpg

Nomenclature

Other Names:

Historical Use of Podophyllum emodi

Podophyllum emodi in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Xiaoyelian

Chinese Name  :

Common Name  :Common Sinopodophyllum Fruit

Specific Name  : Fructus podophylli

Scientific Name:
Collection  : The drug is collected in autumn when ripe, remove from foreign matter and dried.

Description  : Ellipsoidal or subspheroidal, mostly flattened, 3 - 5.5cm long, 2 - 4cm in diameter. Externally purplish red or purplish brown, shrunken, seeds sometimes visible. Apex slightly acute, fruit stalk yellowish brown, mostly fallen. Sarcocarp adhering to pericarp, forming a thin slice, easily broken, containing numerous seeds. Seeds subovoid, about 4mm long, externally reddish-purple with fine furrows and small protrusion at one end. Texture hard, kernel white, oily. Odor slight, taste sour, sweet and astringent, seeds bitter.

Identification  :

Processing  :

Action  : To regulate menstruation and promote the flow of blood.

Indication  : amenorrhea due to blood stasis, difficult labor, missed labor, placenta retention

Precautions  :

Dosage  : 3 to 9 g; usually made into pills or powder.

Storage  : Preserve in a dry place.

Synonymns for Podophyllum emodi

Patent Medicines and Medicines with Multiple Ingredients that include Podophyllum emodi

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Podophyllum emodi in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Hamidreza Ardalani, Amir Avan, Majid Ghayour-Mobarhan
Podophyllotoxin: a novel potential natural anticancer agent.
Avicenna J Phytomed: 2017, 7(4);285-294
[PubMed:28884079] [WorldCat.org] (P p)

Sheng Hu, Qiang Zhou, Wan-Rui Wu, Yi-Xing Duan, Zhi-Yong Gao, Yuan-Wei Li, Qiang Lu
Anticancer effect of deoxypodophyllotoxin induces apoptosis of human prostate cancer cells.
Oncol Lett: 2016, 12(4);2918-2923
[PubMed:27698880] [WorldCat.org] [DOI] (P p)

Yan-Jun Sun, Li-Xin Pei, Kai-Bo Wang, Yin-Shi Sun, Jun-Min Wang, Yan-Li Zhang, Mei-Ling Gao, Bao-Yu Ji
Preparative Isolation of Two Prenylated Biflavonoids from the Roots and Rhizomes of Sinopodophyllum emodi by Sephadex LH-20 Column and High-Speed Counter-Current Chromatography.
Molecules: 2015, 21(1);E10
[PubMed:26703555] [WorldCat.org] [DOI] (I e)

Tingting Liu, Lei Yang, Xiaoyu Sui, Jie Zhang, Li Li, Shuang Fu, Wenjing Li, Xin Liang
Vacuum-powered bubble-assisted solvent extraction followed by macroporous resin enrichment for isolation of podophyllotoxin from Sinopodophyllum emodi.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.: 2015, 1002;364-71
[PubMed:26363371] [WorldCat.org] [DOI] (I p)

Ningwei Lu, Qiong An, Ning Li, Yuming Dong
RP-HPLC method using one marker for quantification of four podophyllum lignans in medicinal plants.
J Chromatogr Sci: 2014, 52(6);514-9
[PubMed:23766105] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects