Pinellia ternata
Contents
- 1 Nomenclature
- 2 Historical Use of Pinellia ternata
- 3 Background
- 4 Nomenclature
- 5 Historical Use of Pinellia ternata
- 6 Background
- 7 Nomenclature
- 8 Historical Use of Pinellia ternata
- 9 Background
- 10 Nomenclature
- 11 Historical Use of Pinellia ternata
- 12 Background
- 13 Nomenclature
- 14 Historical Use of Pinellia ternata
- 15 Background
- 16 Nomenclature
- 17 Historical Use of Pinellia ternata
- 18 Background
- 19 Pharmaceutical Information
- 20 Evidence or the Use of Pinellia ternata in the Treatment of Epilepesy
- 21 Safety
Nomenclature
Other Names:
Historical Use of Pinellia ternata
Pinellia ternata in Traditional Chinese Medicine
Background
Fabanxia ·¨°ëÏÄ
Jiangbanxia ½ª°ëÏÄ
Qingbanxia Çå°ëÏÄ
Shengbanxia Éú°ëÏÄ
Chinese Name (pinyin): Banxia
Chinese Name :
Common Name :Pinellia Tuber
Specific Name : Rhizoma pinelliae
Scientific Name:
Collection : The drug is collected in summer and autumn, wash clean removed from the outer bark and fibrous root and dried in t the sun.
Description : Sub-spheroidal, some slightly oblique. 1 - 1.5 cm in diameter. Externally white or yellowish, apex marked with a dented stem scar, sub-rounded by close and dotted root scars. Base obtuse and rounded and relatively smooth. Texture hard fracture white and starchy. Odourless, taste pungent with numbing and irritating sensation.
Identification : 1.Powder: Whitish, starch granules fairly abundant, simple sub-rounded, polygonal. 2 - 20 µm in diameter, hilum slit shape, V shaped or stellate, compound granules 2 - 6 components. Raphides of calcium oxalate embedded in elliptical mucilage cells or scattered throughout, needle crystals 20 - 110 µm long. Spiral vessels 10 - 24 µm in diameter.2.To 1 g of the powder add 10 ml of methanol. Extract under reflux for 30 minutes, filter, evaporate the filtrate to about 0.5 ml as the test solution. Dissolve arginine CRS, alanine CRS, valine CRS and lucine CRS in 70% of methanol to produce a solution containing 1 mg of each per ml as the as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G containing sodium carboxymethyl cellulose as the coating substance and n-butanol-glacial acetic acid-water (8:3:1) as the mobile phase. Apply separately 5 µl of the test solution. 1 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air. Spray with ninhydrin TS. Heat at 105ºC for several minutes. The spot in the chromatogram obtained with the test solution correspond in position and color to the spot in the chromatogram obtained with the reference solution.
Processing : Rhizome Pinelliae (unprocessed): Eliminate foreign matter. Break to pieces before use.Rhizome Pinelliae (processed with alum): Grade clean according to size, soak in 8% alum solution until the center of the cut surface is devoid or a dry core and the drug has a slight numbing taste. Take out, wash well, cut into thick slices and dry, using 20 kg of alumen per 100 kg of Rhizoma Pinelliae. Elliptical sub-rounded or irregular pieces, cut surface grey to greyish white, bundles trace visible, greyish white, pointed or short line shape, purplish red striations under the remaining cork. Texture fragile, easily broken, fracture horny, odor slight, taste slightly salty, astringent and numb.Rhiome Pinelliae (processed with ginger): Grade clean according to size, soak in water until the center of the cut surface is devoid of a dry core. Add alumen and the decocted slices of Rhizoma Zingeberis Recens to Rhizoma Pinelliae, boil thoroughly. Take out, dry in the air to half dryness, then cut into thin slices and dry. Using 25kg of Rhizoma Zingiberis Recens and 12.5 kg of Rhizoma Pinelliae. It is flaky, irregular pieces or subspheroidal complete tubers. Externally brown to dark brown. Texture hard and fragile, fracture pale yellowish brown frequently horny and lustrous. Odor slight aromatic, taste weak slight with numbing and viscous on chewing.
Action : To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium.
Indication : cough and asthma with much phlegm; dizziness and palpitation due to retention of phlegm and fluid; vertigo caused by wind-phlegm; headache with cold extremities due to attack of phlegm; stuffiness in the chest and epigastrium; globus hystericus;
mixed with ginger: often used for relieving nausea and vomiting
processed with alum: for removing dap heat and phlegm
externally: boils, sores, lymphadenitis
Precautions :
Dosage : 3 to 9 g; for external use, appropriate quantity to be rubbed into juice or ground into powder and applied topially after mixing with liquor.
Storage : Preserve in a ventilated and dry place, protected from moth.
Nomenclature
Other Names:
Historical Use of Pinellia ternata
Pinellia ternata in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Fabanxia
Chinese Name :
Common Name :Pinellia Tuber with Radix Glycyrrhizae and lime
Specific Name : Rhizoma Pinelliae preparata
Scientific Name:
Collection :
Description : Sub-spherical or broken into irregular granules. Externally: yellowish white, yellow or brownish yellow. Texture fragile, loose or hard, granules hard and fragile slightly. Fracture yellow or greyish yellow. Odor slight, taste slightly sweetish and slight numbing.
Identification : 1.Powder: Pale yellow to yellow, identical with the examination as described under the test (1) of Rhizome Pinelliae.2.To 2 g of the powder, add 2 ml of hydrochloric acid and 20 ml of chloroform, heat under reflux for 1 hour, cool, filter. Evaporate the filtrate to dryness. Dissolve the residue in 0.5 ml of absolute ethanol as the test solution. Dissolve glycyrrhetinic acid CRS in absolute ethanol to produce a solution containing 1 mg per ml as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel GF254 as the coating substance and petroleum (30 - 60ºC) benzene-ethyl acetate-glacial acetic acid (10:20:7: 0.5) as the mobile phase. Apply separately 5 µl of test solution, 2 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air and examine under ultra violet light (254 nm). The dark red spot in the chromatogram obtained with the test solution correspond in position to the spot in the chromatogram obtained with the reference solution.
Processing : Grade clean Rhizome Pinelliae according to size, soak in water until no dry core at the central portion of the drug and take out. Decoct liqourice with a quantity of water twice, combine the decoctions and pour into a lime with prepared with suitable amount of water, stir evenly. Add the soak rhizome and stir 1 - 2 times everyday, maintain the solution over pH 12 until the cut surface becomes yellow evenly and taste slight numbing sensation. Take out wash clean and dry in the shade or heat. To each 100kg of Rhizoma Pinelliae add 15 kg of liquorice and 10 kg of lime.
Action :
Indication : cough and asthma with much phlegm; dizziness and palpitation due to retention of phlegm and fluid; vertigo caused by wind-phlegm; headache with cold extremities due to attack of phlegm
Precautions :
Dosage :
Storage :
Nomenclature
Other Names:
Historical Use of Pinellia ternata
Pinellia ternata in Traditional Chinese Medicine
Background
Fabanxia ·¨°ëÏÄ
Jiangbanxia ½ª°ëÏÄ
Qingbanxia Çå°ëÏÄ
Shengbanxia Éú°ëÏÄ
Chinese Name (pinyin): Banxia
Chinese Name :
Common Name :Pinellia Tuber
Specific Name : Rhizoma pinelliae
Scientific Name:
Collection : The drug is collected in summer and autumn, wash clean removed from the outer bark and fibrous root and dried in t the sun.
Description : Sub-spheroidal, some slightly oblique. 1 - 1.5 cm in diameter. Externally white or yellowish, apex marked with a dented stem scar, sub-rounded by close and dotted root scars. Base obtuse and rounded and relatively smooth. Texture hard fracture white and starchy. Odourless, taste pungent with numbing and irritating sensation.
Identification : 1.Powder: Whitish, starch granules fairly abundant, simple sub-rounded, polygonal. 2 - 20 µm in diameter, hilum slit shape, V shaped or stellate, compound granules 2 - 6 components. Raphides of calcium oxalate embedded in elliptical mucilage cells or scattered throughout, needle crystals 20 - 110 µm long. Spiral vessels 10 - 24 µm in diameter.2.To 1 g of the powder add 10 ml of methanol. Extract under reflux for 30 minutes, filter, evaporate the filtrate to about 0.5 ml as the test solution. Dissolve arginine CRS, alanine CRS, valine CRS and lucine CRS in 70% of methanol to produce a solution containing 1 mg of each per ml as the as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G containing sodium carboxymethyl cellulose as the coating substance and n-butanol-glacial acetic acid-water (8:3:1) as the mobile phase. Apply separately 5 µl of the test solution. 1 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air. Spray with ninhydrin TS. Heat at 105ºC for several minutes. The spot in the chromatogram obtained with the test solution correspond in position and color to the spot in the chromatogram obtained with the reference solution.
Processing : Rhizome Pinelliae (unprocessed): Eliminate foreign matter. Break to pieces before use.Rhizome Pinelliae (processed with alum): Grade clean according to size, soak in 8% alum solution until the center of the cut surface is devoid or a dry core and the drug has a slight numbing taste. Take out, wash well, cut into thick slices and dry, using 20 kg of alumen per 100 kg of Rhizoma Pinelliae. Elliptical sub-rounded or irregular pieces, cut surface grey to greyish white, bundles trace visible, greyish white, pointed or short line shape, purplish red striations under the remaining cork. Texture fragile, easily broken, fracture horny, odor slight, taste slightly salty, astringent and numb.Rhiome Pinelliae (processed with ginger): Grade clean according to size, soak in water until the center of the cut surface is devoid of a dry core. Add alumen and the decocted slices of Rhizoma Zingeberis Recens to Rhizoma Pinelliae, boil thoroughly. Take out, dry in the air to half dryness, then cut into thin slices and dry. Using 25kg of Rhizoma Zingiberis Recens and 12.5 kg of Rhizoma Pinelliae. It is flaky, irregular pieces or subspheroidal complete tubers. Externally brown to dark brown. Texture hard and fragile, fracture pale yellowish brown frequently horny and lustrous. Odor slight aromatic, taste weak slight with numbing and viscous on chewing.
Action : To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium.
Indication : cough and asthma with much phlegm; dizziness and palpitation due to retention of phlegm and fluid; vertigo caused by wind-phlegm; headache with cold extremities due to attack of phlegm; stuffiness in the chest and epigastrium; globus hystericus;
mixed with ginger: often used for relieving nausea and vomiting
processed with alum: for removing dap heat and phlegm
externally: boils, sores, lymphadenitis
Precautions :
Dosage : 3 to 9 g; for external use, appropriate quantity to be rubbed into juice or ground into powder and applied topially after mixing with liquor.
Storage : Preserve in a ventilated and dry place, protected from moth.
Nomenclature
Other Names:
Historical Use of Pinellia ternata
Pinellia ternata in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Fabanxia
Chinese Name :
Common Name :Pinellia Tuber with Radix Glycyrrhizae and lime
Specific Name : Rhizoma Pinelliae preparata
Scientific Name:
Collection :
Description : Sub-spherical or broken into irregular granules. Externally: yellowish white, yellow or brownish yellow. Texture fragile, loose or hard, granules hard and fragile slightly. Fracture yellow or greyish yellow. Odor slight, taste slightly sweetish and slight numbing.
Identification : 1.Powder: Pale yellow to yellow, identical with the examination as described under the test (1) of Rhizome Pinelliae.2.To 2 g of the powder, add 2 ml of hydrochloric acid and 20 ml of chloroform, heat under reflux for 1 hour, cool, filter. Evaporate the filtrate to dryness. Dissolve the residue in 0.5 ml of absolute ethanol as the test solution. Dissolve glycyrrhetinic acid CRS in absolute ethanol to produce a solution containing 1 mg per ml as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel GF254 as the coating substance and petroleum (30 - 60ºC) benzene-ethyl acetate-glacial acetic acid (10:20:7: 0.5) as the mobile phase. Apply separately 5 µl of test solution, 2 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air and examine under ultra violet light (254 nm). The dark red spot in the chromatogram obtained with the test solution correspond in position to the spot in the chromatogram obtained with the reference solution.
Processing : Grade clean Rhizome Pinelliae according to size, soak in water until no dry core at the central portion of the drug and take out. Decoct liqourice with a quantity of water twice, combine the decoctions and pour into a lime with prepared with suitable amount of water, stir evenly. Add the soak rhizome and stir 1 - 2 times everyday, maintain the solution over pH 12 until the cut surface becomes yellow evenly and taste slight numbing sensation. Take out wash clean and dry in the shade or heat. To each 100kg of Rhizoma Pinelliae add 15 kg of liquorice and 10 kg of lime.
Action :
Indication : cough and asthma with much phlegm; dizziness and palpitation due to retention of phlegm and fluid; vertigo caused by wind-phlegm; headache with cold extremities due to attack of phlegm
Precautions :
Dosage :
Storage :
Nomenclature
Other Names:
Historical Use of Pinellia ternata
Pinellia ternata in Traditional Chinese Medicine
Background
Fabanxia ·¨°ëÏÄ
Jiangbanxia ½ª°ëÏÄ
Qingbanxia Çå°ëÏÄ
Shengbanxia Éú°ëÏÄ
Chinese Name (pinyin): Banxia
Chinese Name :
Common Name :Pinellia Tuber
Specific Name : Rhizoma pinelliae
Scientific Name:
Collection : The drug is collected in summer and autumn, wash clean removed from the outer bark and fibrous root and dried in t the sun.
Description : Sub-spheroidal, some slightly oblique. 1 - 1.5 cm in diameter. Externally white or yellowish, apex marked with a dented stem scar, sub-rounded by close and dotted root scars. Base obtuse and rounded and relatively smooth. Texture hard fracture white and starchy. Odourless, taste pungent with numbing and irritating sensation.
Identification : 1.Powder: Whitish, starch granules fairly abundant, simple sub-rounded, polygonal. 2 - 20 µm in diameter, hilum slit shape, V shaped or stellate, compound granules 2 - 6 components. Raphides of calcium oxalate embedded in elliptical mucilage cells or scattered throughout, needle crystals 20 - 110 µm long. Spiral vessels 10 - 24 µm in diameter.2.To 1 g of the powder add 10 ml of methanol. Extract under reflux for 30 minutes, filter, evaporate the filtrate to about 0.5 ml as the test solution. Dissolve arginine CRS, alanine CRS, valine CRS and lucine CRS in 70% of methanol to produce a solution containing 1 mg of each per ml as the as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G containing sodium carboxymethyl cellulose as the coating substance and n-butanol-glacial acetic acid-water (8:3:1) as the mobile phase. Apply separately 5 µl of the test solution. 1 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air. Spray with ninhydrin TS. Heat at 105ºC for several minutes. The spot in the chromatogram obtained with the test solution correspond in position and color to the spot in the chromatogram obtained with the reference solution.
Processing : Rhizome Pinelliae (unprocessed): Eliminate foreign matter. Break to pieces before use.Rhizome Pinelliae (processed with alum): Grade clean according to size, soak in 8% alum solution until the center of the cut surface is devoid or a dry core and the drug has a slight numbing taste. Take out, wash well, cut into thick slices and dry, using 20 kg of alumen per 100 kg of Rhizoma Pinelliae. Elliptical sub-rounded or irregular pieces, cut surface grey to greyish white, bundles trace visible, greyish white, pointed or short line shape, purplish red striations under the remaining cork. Texture fragile, easily broken, fracture horny, odor slight, taste slightly salty, astringent and numb.Rhiome Pinelliae (processed with ginger): Grade clean according to size, soak in water until the center of the cut surface is devoid of a dry core. Add alumen and the decocted slices of Rhizoma Zingeberis Recens to Rhizoma Pinelliae, boil thoroughly. Take out, dry in the air to half dryness, then cut into thin slices and dry. Using 25kg of Rhizoma Zingiberis Recens and 12.5 kg of Rhizoma Pinelliae. It is flaky, irregular pieces or subspheroidal complete tubers. Externally brown to dark brown. Texture hard and fragile, fracture pale yellowish brown frequently horny and lustrous. Odor slight aromatic, taste weak slight with numbing and viscous on chewing.
Action : To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium.
Indication : cough and asthma with much phlegm; dizziness and palpitation due to retention of phlegm and fluid; vertigo caused by wind-phlegm; headache with cold extremities due to attack of phlegm; stuffiness in the chest and epigastrium; globus hystericus;
mixed with ginger: often used for relieving nausea and vomiting
processed with alum: for removing dap heat and phlegm
externally: boils, sores, lymphadenitis
Precautions :
Dosage : 3 to 9 g; for external use, appropriate quantity to be rubbed into juice or ground into powder and applied topially after mixing with liquor.
Storage : Preserve in a ventilated and dry place, protected from moth.
Nomenclature
Other Names:
Historical Use of Pinellia ternata
Pinellia ternata in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Fabanxia
Chinese Name :
Common Name :Pinellia Tuber with Radix Glycyrrhizae and lime
Specific Name : Rhizoma Pinelliae preparata
Scientific Name:
Collection :
Description : Sub-spherical or broken into irregular granules. Externally: yellowish white, yellow or brownish yellow. Texture fragile, loose or hard, granules hard and fragile slightly. Fracture yellow or greyish yellow. Odor slight, taste slightly sweetish and slight numbing.
Identification : 1.Powder: Pale yellow to yellow, identical with the examination as described under the test (1) of Rhizome Pinelliae.2.To 2 g of the powder, add 2 ml of hydrochloric acid and 20 ml of chloroform, heat under reflux for 1 hour, cool, filter. Evaporate the filtrate to dryness. Dissolve the residue in 0.5 ml of absolute ethanol as the test solution. Dissolve glycyrrhetinic acid CRS in absolute ethanol to produce a solution containing 1 mg per ml as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel GF254 as the coating substance and petroleum (30 - 60ºC) benzene-ethyl acetate-glacial acetic acid (10:20:7: 0.5) as the mobile phase. Apply separately 5 µl of test solution, 2 µl of the reference solution to the plate. After developing and removal of the plate, dry it in the air and examine under ultra violet light (254 nm). The dark red spot in the chromatogram obtained with the test solution correspond in position to the spot in the chromatogram obtained with the reference solution.
Processing : Grade clean Rhizome Pinelliae according to size, soak in water until no dry core at the central portion of the drug and take out. Decoct liqourice with a quantity of water twice, combine the decoctions and pour into a lime with prepared with suitable amount of water, stir evenly. Add the soak rhizome and stir 1 - 2 times everyday, maintain the solution over pH 12 until the cut surface becomes yellow evenly and taste slight numbing sensation. Take out wash clean and dry in the shade or heat. To each 100kg of Rhizoma Pinelliae add 15 kg of liquorice and 10 kg of lime.
Action :
Indication : cough and asthma with much phlegm; dizziness and palpitation due to retention of phlegm and fluid; vertigo caused by wind-phlegm; headache with cold extremities due to attack of phlegm
Precautions :
Dosage :
Storage :
Synonymns for Pinellia ternata
Patent Medicines and Medicines with Multiple Ingredients that include Pinellia ternata
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Pinellia ternata in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Chen Bo, Mengmeng Liu, Qian You, Xiao Liu, Yanfang Zhu, Yongbo Duan, Dexin Wang, Tao Xue, Jianping Xue
Integrated analysis of transcriptome and miRNAome reveals the heat stress response of Pinellia ternata seedlings.
BMC Genomics: 2024, 25(1);398
[PubMed:38654150]
[WorldCat.org]
[DOI]
(I e)
Jialei Chen, Jialu Wang, Li Liu, Yifei Pei, Ziyi Liu, Xue Feng, Xiwen Li
Transcriptomic and metabolomic profiling provide insight into the role of sugars and hormones in leaf senescence of Pinellia ternata.
Plant Cell Rep: 2024, 43(5);125
[PubMed:38647720]
[WorldCat.org]
[DOI]
(I e)
Minglei Ge, Huizi Ouyang, Ye Shang, Abdulmumin Muhammad Biu, Xiwei Wu, Caixia Li, Fanjiao Zuo, Yameng Zhu, Zixiang Xue, Jia Hao, Jun He
Investigation of the drug-drug interaction and incompatibility mechanism between Aconitum carmichaelii Debx and Pinellia ternata (Thunb.) Breit.
J Ethnopharmacol: 2024, 330;118212
[PubMed:38636577]
[WorldCat.org]
[DOI]
(I a)
Haijiao Shi, Miao Sun, Shuai Wang, Fanyu He, Ronglai Yang, Zheng Li, Wei Chen, Fengrong Wang
Jiawei Dachaihu decoction protects against mitochondrial dysfunction in atherosclerosis (AS) mice with chronic unpredictable mild stress (CUMS) via SIRT1/PGC-1α/TFAM/LON signaling pathway.
J Ethnopharmacol: 2024;118150
[PubMed:38631487]
[WorldCat.org]
[DOI]
(I a)
Fan Feng, Ping Hu, Lei Peng, Jun Chen, Xingkui Tao
Mechanism Research of PZD Inhibiting Lung Cancer Cell Proliferation, Invasion, and Migration Based on Network Pharmacology.
Curr Pharm Des: 2024;
[PubMed:38571356]
[WorldCat.org]
[DOI]
(I a)