Picrasma quassioides

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Nomenclature

Other Names:

Historical Use of Picrasma quassioides

Picrasma quassioides in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Kumu

Chinese Name  :

Common Name  :Indian Quassiawood

Specific Name  : Ramulus et folium picrasmae

Scientific Name:
Collection  : The drug is collected in summer and autumn and dried.

Description  : Stems cylindrical, varying in length, 0.5 - 2 cm in diameter, externally greyish green or brownish green with fine and dense longitudinal striations and numerous dotted lenticels, texture fragile, easily broken, fracture uneven, pale yellow, the young branches pale colored and large medullated, compound leaves odd pinnate easily falling off, leaflets ovate elongated elliptical or ovate lanceolate, subsessile, 4 - 16 cm long, 1.5 - 6 cm wide, apex acute, base oblique or slightly rounded, margins crenate both surface usually green. Sometimes the lower surface pale purplish red. Pubescent along the midrib. Odour slight, taste extremely bitter

Identification  : 1.Powder: yellowish green, upper epidermal cells of the leaf polygonal, stomata anomocytic, usually visible on the lower epidermal. Mesophyll cells frequently containing clusters of calcium oxalate, fibre bundles subrounded by parenchymatous cells containing of clusters of calcium oxalate, forming crystal fibres.2.Macerate 1g of the powder in 10 ml methanol overnight, filter and evaporate the filtrate to dryness. Dissolve the residue in 10 ml of methanol and use it as the test solution. Prepare a solution of Ramulus et Folium Picrasme reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G containing sodium carboxymethyl cellulose as the coating substance and a mixture of chloroform-methanol (85:15) as the mobile phase. Apply separately 10 µl of each of the above two solutions to the plate. After developing and removal of the plate, dry it in the air. Spray with modified potassium iodobismuthate TS. A spot in the chromatogram obtained from the test solution correspond in colour and position to the spot in the chromatogram obtained from the reference drug solution.

Processing  : Eliminate foreign matter, wash the stems clean, soften thoroughly, cut into slices and dry in the sun. Spray the leaves with clean water, moisten briefly, cut into slivers and dry in the sun.

Action  : To act against bacteria and relieve inflammation, to remove damp, and to counteract toxicity.

Indication  : colds, acute tonsilitis, pharyngitis, colitis, bacillary dysentery, eczema, boils, venomous snake bite

Precautions  :

Dosage  : 3 to 4.5 g of its branches or 1 to 3 g of its leaves; appropriate quantity for external use.

Storage  : Preserve in a dry place.

Synonymns for Picrasma quassioides

Patent Medicines and Medicines with Multiple Ingredients that include Picrasma quassioides

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Picrasma quassioides in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Rui Xu, Dongdong Zhang, Fangfang Shu, Zehai Long, Yiming Li, Zhengtao Wang, Li Yang, Rui Wang
Picraquanines A-C, three new phenolic derivatives from the stems of Picrasma quassioides.
Nat. Prod. Res.: 2020;1-7
[PubMed:32056448] [WorldCat.org] [DOI] (I a)

Jie Zhang, Chuan-Xi Wang, Xiao-Jun Song, Shuang Li, Huan Zhao, Guo-Dong Chen, Dan Hu, Hao Gao, Xin-Sheng Yao
A pair of new tirucallane triterpenoid epimers from the stems of Picrasma quassioides.
Chin J Nat Med: 2019, 17(12);906-911
[PubMed:31882044] [WorldCat.org] [DOI] (I p)

Cui He, Yaqi Wang, Tingmi Yang, Hengshan Wang, Haibing Liao, Dong Liang
##Title##
J. Agric. Food Chem.: 2020, 68(1);117-127
[PubMed:31820963] [WorldCat.org] [DOI] (I p)

Fangfei Li, Hanxun Wang, Ying Wang, Shasha Feng, Baichun Hu, Xiangyu Zhang, Jian Wang, Wei Li, Maosheng Cheng
Computational investigation reveals Picrasidine C as selective PPARα lead: binding pattern, selectivity mechanism and ADME/tox profile.
J. Biomol. Struct. Dyn.: 2019;1-18
[PubMed:31787028] [WorldCat.org] [DOI] (I a)

Jie Zhang, Chuan-Xi Wang, Xiao-Jun Song, Shuang Li, Cai-Lian Fan, Guo-Dong Chen, Dan Hu, Xin-Sheng Yao, Hao Gao
A new cinnamamide derivative and two new β-carboline alkaloids from the stems of Picrasma quassioides.
Fitoterapia: 2019, 139;104375
[PubMed:31629050] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects