- 1 Nomenclature
- 2 Historical Use of Picrasma quassioides
- 3 Background
- 4 Pharmaceutical Information
- 5 Evidence or the Use of Picrasma quassioides in the Treatment of Epilepesy
- 6 Safety
Historical Use of Picrasma quassioides
Picrasma quassioides in Traditional Chinese Medicine
Chinese Name (pinyin): Kumu
Chinese Name :
Common Name :Indian Quassiawood
Specific Name : Ramulus et folium picrasmae
Collection : The drug is collected in summer and autumn and dried.
Description : Stems cylindrical, varying in length, 0.5 - 2 cm in diameter, externally greyish green or brownish green with fine and dense longitudinal striations and numerous dotted lenticels, texture fragile, easily broken, fracture uneven, pale yellow, the young branches pale colored and large medullated, compound leaves odd pinnate easily falling off, leaflets ovate elongated elliptical or ovate lanceolate, subsessile, 4 - 16 cm long, 1.5 - 6 cm wide, apex acute, base oblique or slightly rounded, margins crenate both surface usually green. Sometimes the lower surface pale purplish red. Pubescent along the midrib. Odour slight, taste extremely bitter
Identification : 1.Powder: yellowish green, upper epidermal cells of the leaf polygonal, stomata anomocytic, usually visible on the lower epidermal. Mesophyll cells frequently containing clusters of calcium oxalate, fibre bundles subrounded by parenchymatous cells containing of clusters of calcium oxalate, forming crystal fibres.2.Macerate 1g of the powder in 10 ml methanol overnight, filter and evaporate the filtrate to dryness. Dissolve the residue in 10 ml of methanol and use it as the test solution. Prepare a solution of Ramulus et Folium Picrasme reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G containing sodium carboxymethyl cellulose as the coating substance and a mixture of chloroform-methanol (85:15) as the mobile phase. Apply separately 10 µl of each of the above two solutions to the plate. After developing and removal of the plate, dry it in the air. Spray with modified potassium iodobismuthate TS. A spot in the chromatogram obtained from the test solution correspond in colour and position to the spot in the chromatogram obtained from the reference drug solution.
Processing : Eliminate foreign matter, wash the stems clean, soften thoroughly, cut into slices and dry in the sun. Spray the leaves with clean water, moisten briefly, cut into slivers and dry in the sun.
Action : To act against bacteria and relieve inflammation, to remove damp, and to counteract toxicity.
Indication : colds, acute tonsilitis, pharyngitis, colitis, bacillary dysentery, eczema, boils, venomous snake bite
Dosage : 3 to 4.5 g of its branches or 1 to 3 g of its leaves; appropriate quantity for external use.
Storage : Preserve in a dry place.
Synonymns for Picrasma quassioides
Patent Medicines and Medicines with Multiple Ingredients that include Picrasma quassioides
Evidence or the Use of Picrasma quassioides in the Treatment of Epilepesy
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
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