Phytolacca acinosa

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Other Names:

Historical Use of Phytolacca acinosa

Phytolacca acinosa in Traditional Chinese Medicine


Shanglugen É̽¸ù Chinese Name (pinyin): Shanglu

Chinese Name  :

Common Name  :Phytolacca Root

Specific Name  : Radix phytolaccae

Scientific Name:
Collection  : The drug is collected from autumn to next spring, remove from rootlet and soil, cut into slice or piece and cried in the sun or in the shade.

Description  : Irregular slices or pieces, cut transversely or longitudinally, varying thickness. The outer bark greyish yellow or greyish brown. Transversely cut pieces tortous with shrunken edges, 2 - 8 cm in diameter. Cut surface pale yellowish brown or yellowish white, wood prominent, forming several bulged concentric rings. Longitudinally cut pieces curved or rolled, 5 - 8 cm long, 1 - 2 cm wide, wood showing parallel, bulged stripes. Texture hard, odour slight, taste slightly sweet and numb after chewing for a long time.

Identification  : Transverse section:Root of Phytolacca acinosa: Cork consisting of several to over 10 layers of cells, cortex narrow. Fibro vascular tissue forming structure with several concentric cambium rings, each having dozens of vascular bundles. Phloem at the outer side of vascular bundles. Xylem at the inner side, wood fibres numerous, often several ones grouped or around the vessels. Parenchymatous cells containing raphides of calcium oxalate, a few containing prisms or clusters of calcium oxalate, also containing starch granules. Powder: Greyish white, needle crystals of calcium oxalate in bundles or scattered throughout, needle crystal fine, raphides, 40 - 72 µm long, prims or clusters of calcium oxalate observed. Wood fibres mostly in bundles, 10 - 20µm in diameter, walls thickened or slightly thickened with numerous X-shaped pits. Cork cells brownish yellow, rectangular or polygonal, some containing granules. Starch granules simple, subrounded or oblong, 3 - 28 µm in diameter, hilum cleft like, pointed stellate and V shaped, striations indistinct, compound granules rare of 2 - 3 components.Root of Phytolacca americana: Raphides of calcium oxalate relatively long up to 98 µm, prisms and clusters absent

Processing  : Eliminate foreign matterProcessed with vinegar: Stir fry the clean Radix Phytolocae as described under the method for stir frying with vinegar (Appendix ll D) to dryness using 30 kg of vinegar per 100 kg of Radix Phytolocae.

Action  : To cause drastic purgation and also diuresis, to counteract toxicity, and to reduce nodulation.

Indication  : anasarca with oliguria; and constipation external: carbuncles and sores

Precautions  : Contraindicated in pregnancy.

Dosage  : 3 to 9 g; for external use, appropriate quantity of the fresh root to be pounded into paste or the dried root to be ground into powder, and applied topically.

Storage  : Preserve in a dry place, protected from mould and moth.

Synonymns for Phytolacca acinosa

Patent Medicines and Medicines with Multiple Ingredients that include Phytolacca acinosa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Phytolacca acinosa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Yi Tao, Enci Jiang, Baochang Cai
Development of an ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry method for comparative pharmacokinetics of six triterpenoids in rat plasma and application to different forms of Phytolacca acinosa.
J Sep Sci: 2020;
[PubMed:31930669] [] [DOI] (I a)

Nicolas Grosjean, Marie Le Jean, Charlotte Berthelot, Michel Chalot, Elisabeth Maria Gross, Damien Blaudez
Accumulation and fractionation of rare earth elements are conserved traits in the Phytolacca genus.
Sci Rep: 2019, 9(1);18458
[PubMed:31804509] [] [DOI] (I e)

Guo Yu, Jie Liu, Yumei Long, Zhe Chen, Geoffrey I Sunahara, Pingping Jiang, Shaohong You, Hua Lin, He Xiao
Phytoextraction of cadmium-contaminated soils: comparison of plant species and low molecular weight organic acids.
Int J Phytoremediation: 2019;1-9
[PubMed:31522543] [] [DOI] (I a)

Dipika Rana, Anupam Bhatt, Brij Lal
Ethnobotanical knowledge among the semi-pastoral Gujjar tribe in the high altitude (Adhwari's) of Churah subdivision, district Chamba, Western Himalaya.
J Ethnobiol Ethnomed: 2019, 15(1);10
[PubMed:30744678] [] [DOI] (I e)

Fukushi Abekura, Junyoung Park, Choong-Hwan Kwak, Sun-Hyung Ha, Seung-Hak Cho, Young-Chae Chang, Ki-Tae Ha, Hyeun-Wook Chang, Young-Choon Lee, Tae-Wook Chung, Cheorl-Ho Kim
Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells.
Int. Immunopharmacol.: 2019, 68;156-163
[PubMed:30639961] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects