Peucedanum praeruptorum

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Nomenclature

Other Names:

Historical Use of Peucedanum praeruptorum

Peucedanum praeruptorum in Traditional Chinese Medicine

Background

Nenqianhu ÄÛÇ°ºú Chinese Name (pinyin): Qianhu

Chinese Name  :

Common Name  :Peucedanum Root

Specific Name  : Radix peucedani

Scientific Name:
Collection  : The drug is collected in winter and next spring, when stem and leaves wither or before floral stem grows, remove from rootlet, wash clean and dried in the sun or at a low temperature.

Description  : Root of Peucedanum praeruptorum: Irregular cylindrical, conical or fusiform, slightly twisted, the lower part frequently branched. 3 - 15 cm long, 1 - 2 cm in diameter. Externally blackish brown or greyish yellow frequently with stem scars and fibrous remains of pericladia at the root stock with numerous fine annular striations at the upper end and longitudinally furrowed or wrinkled with transverse lenticels at the lower part. Texture relatively flexible, hard when dried, easily broken, fracture uneven, pale yellowish white. Numerous brownish yellow oily spots scattered in cortex, cambium ring brown, rays radiated. Odour aromatic, taste slightly bitter and pungent.

Identification  : 1.Macerate 1 g of the powder in 10 ml of ether for 2 hours. Apply 2 drops of the ether solution respectively to two pieces of filter paper. Examine under ulktra violet light (365 nm), a pale blue fluorescence is shown. Add several drops of 15% sodium hydroxide solution on the spots. the fluorescence disappears after 2 minutes. Protect one piece of filter paper from light and expose to other one to light and examine under ultra violet light after about 3 hours, the spot on the paper exposed to the light shows an intensively blue fluorescence and the spot protected from light shows no fluorescence.2.Heat under reflux 5 g of the powder in 30 ml of ethanol for 10 minutes and filter. Evaporate 2 ml of the filtrate to dryness, Dissolve the residue in 1 ml of glacial acetic acid then add 5 drops of acetyl chloride and a few crystal of zinc chloride and heat on a water bath for 1 - 2 minutes. A red color is producedExtractives: Carry out the cold maceration methanol as described under the determination of ethanol soluble extractives (Appendix X A), using 50% ethanol as the solvent not less than 20.0%.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thin slices and dry in the sun.Processed with honey: Stir fry the slices as described under the method for stir frying with honey (Appendix ll D) until not sticky to the fingers.

Action  : To dispel wind and remove heat, and to relieve cough and resolve phlegm.

Indication  : cough and dyspnea in respiratory infections with copious or yellowish sticky expectoration

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in cool nd dry place, protected from mould and moth.

Synonymns for Peucedanum praeruptorum

Patent Medicines and Medicines with Multiple Ingredients that include Peucedanum praeruptorum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Peucedanum praeruptorum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Yucheng Zhao, Nana Wang, Huali Wu, Yuanze Zhou, Chuanlong Huang, Jun Luo, Zhixiong Zeng, Lingyi Kong
Structure-based tailoring of the first coumarins-specific bergaptol O-methyltransferase to synthesize bergapten for depigmentation disorder treatment.
J Adv Res: 2020, 21;57-64
[PubMed:31666994] [WorldCat.org] [DOI] (P e)

Ling Li Chen, Shan Shan Chu, Ling Zhang, Jin Xie, Min Dai, Xin Wu, Hua Sheng Peng
##Title##
Molecules: 2019, 24(7);
[PubMed:30979075] [WorldCat.org] [DOI] (I e)

Yucheng Zhao, Nana Wang, Ziwei Sui, Chuanlong Huang, Zhixiong Zeng, Lingyi Kong
##Title##
Int J Mol Sci: 2019, 20(7);
[PubMed:30934718] [WorldCat.org] [DOI] (I e)

Xin-Yu Li, Yuan-Yuan Zu, Wei Ning, Ming-Xu Tang, Chi Gong, Sheng-Li Niu, Hui-Ming Hua
##Title##
J Asian Nat Prod Res: 2020, 22(3);287-294
[PubMed:30621449] [WorldCat.org] [DOI] (I p)

Ziwei Sui, Jun Luo, Ruolan Yao, Chuanlong Huang, Yucheng Zhao, Lingyi Kong
Functional characterization and correlation analysis of phenylalanine ammonia-lyase (PAL) in coumarin biosynthesis from Peucedanum praeruptorum Dunn.
Phytochemistry: 2019, 158;35-45
[PubMed:30448740] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects