Perilla frutescens var. crispa
Contents
- 1 Nomenclature
- 2 Historical Use of Perilla frutescens
- 3 Background
- 4 Nomenclature
- 5 Historical Use of Perilla frutescens
- 6 Background
- 7 Nomenclature
- 8 Historical Use of Perilla frutescens
- 9 Background
- 10 Nomenclature
- 11 Historical Use of Perilla frutescens
- 12 Background
- 13 Nomenclature
- 14 Historical Use of Perilla frutescens
- 15 Background
- 16 Nomenclature
- 17 Historical Use of Perilla frutescens
- 18 Background
- 19 Nomenclature
- 20 Historical Use of Perilla frutescens
- 21 Background
- 22 Nomenclature
- 23 Historical Use of Perilla frutescens
- 24 Background
- 25 Pharmaceutical Information
- 26 Evidence or the Use of Perilla frutescens in the Treatment of Epilepesy
- 27 Safety
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Zisugeng
Chinese Name :
Common Name :Perilla Stem
Specific Name : Caulis perillae
Scientific Name:
Collection : The drug is collected in autumn after fruit is ripe, removed from foreign matter and dried in the sun or cut into slices when fresh and dried in the sun.
Description : Square, four angles obtuse, varying in length, 0.5-1.5cm in diameter. Externally purplish-brown or dark purple, with longitudinal furrows and fine longitudinal striations, nodes slightly inflated with opposite branch scars and leaf scars. Texture light and hard, fracture lobed. Slices 2-5mm thick, often rhomboidal, wood yellowish-white, medullary rays fine dense, radiate, pith white, lax or fallen off, odour, slightly aromatic and taste weak.
Identification :
Processing : eliminate foreign matter, soak briefly, soften thoroughly and cut into thick slices and dry.
Action : To regulate the flow of qi and the function of the stomach, to alleviate pain, and to prevent abortion.
Indication : feeling of stuffiness in the chest, epigastralgia, belching and vomiting; threatened abortion
Precautions :
Dosage : 5 to 9 g.
Storage : Preserve in a cool and dry place.
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Lao Sugeng ÀÏËÕ¹£
Suye ËÕÒ¶
Zisuye ×ÏËÕÒ¶
Chinese Name (pinyin): Zisu
Chinese Name :
Common Name :Purple common Perilla
Specific Name : Folium et Caulis Perillae
Scientific Name:
Collection :
Description :
Identification :
Processing :
Action :
Indication :
Precautions :
Dosage : 6-12g for decocted/30-60g for fish or crab poisoning
Storage :
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Zisuye
Chinese Name :
Common Name :Perilla Leaf
Specific Name : Folium perillae
Scientific Name:
Collection : The drug is collected in summer when foliage branch growing luxuriantly, removed from foreign matter and dried in the sun.
Description : Mostly crumpled, rolled and broken, when whole, ovate, 4 0 11cm long, 2.5 - 9cm wide, apex long acuminate or acute, base rounded or broadly cuneate, margin crenate. Both surface purple or upper surface green and the lower purple with scattered greyish white hairs and numerous point shaped glandular scales, petioles 2 - 7mm in diameter, purplish green with a pith in the center of fructure, odor delicately aromatic, taste slightly pungent.
Identification : 1.Leaf in the surface view: Some epidermal cells containing purplish pigment, a red color is produced immediately on adding 10% hydrochloric acid nsolution, or a green color is produced on adding 5% potassium hydroxide solution, subsequently cahnged to yellowish green.2.To 0.7g of the powder in a round bottom flask add 250ml of water, mix well and connect the flask with volatile oil determination apparatus. Add water from the top of the apparatus until it reaches the mark and overflows to the flask. Add to the flask 1.5ml of petroleum ether (60 - 90ºC) and connect the flask to boil and continue heating to gentle boiling for 2 hours, cool, separate the petroleum ether layer and used it as the test solution. Prepare the solution of 0.7g Folium Perillae reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G as the coating substance and petroleum ether (60 - 90ºC)-ethyl acetate (19:1) as the mobile phase. Apply separately 10µl each of the two solutions to the plate. After developing (with 15cm developing distance) and removal of the plate, dry it in the air, spray with dinitrophenylhrdrazine TS and wait. The spots in the chromatogram obtained with the test solution correspond in position and color to the spots in the chromatogram obtained with the reference dreug solution.
Processing : Eliminate foreign matter and old branches, spray with water, cut into pieces and dry.
Action : To induce perspiration and dispel cold, and to regulate the stomach function.
Indication : common cold with cough and nausea; vomiting of pregnancy; fish or crab poisoning
Precautions :
Dosage : 4.5 to 9 g.
Storage : Preserve in a cool and dry place.
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Chaosuzi ³´ËÕ×Ó
Suzi ËÕ×Ó
Chinese Name (pinyin): Zisuzi
Chinese Name :
Common Name :Perilla Fruit
Specific Name : Fructus perillae
Scientific Name:
Collection : The drug is collected in autumn when ripe, remove from foreign matter and dried in the sun.
Description : Ovoid or subspherical, 1.5mm in diameter. Externally greyish brown with dark purple and slightly protuberant reticulate striations, base slightly acute with greyish white and pointed fruit stalk scar. Pericarp thin and fragile, easily broken, seeds yellowish white, testa membranous, cotyledons 2, whitish and oily, odor aromatic on pressing, taste slightly pungent.
Identification :
Processing : Eliminate foreign matter, wash, clean and dry.Stir fried: stir fry as described under the method of simple stir frying (Appendix ll D) until the drug burst.
Action : To relieve dyspnea and cough, to eliminate phlegm, and to relax bowels.
Indication :
Precautions :
Dosage : 3 to 9 g.
Storage : Preserve in a ventilated and dry place, protected from moth.
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Zisugeng
Chinese Name :
Common Name :Perilla Stem
Specific Name : Caulis perillae
Scientific Name:
Collection : The drug is collected in autumn after fruit is ripe, removed from foreign matter and dried in the sun or cut into slices when fresh and dried in the sun.
Description : Square, four angles obtuse, varying in length, 0.5-1.5cm in diameter. Externally purplish-brown or dark purple, with longitudinal furrows and fine longitudinal striations, nodes slightly inflated with opposite branch scars and leaf scars. Texture light and hard, fracture lobed. Slices 2-5mm thick, often rhomboidal, wood yellowish-white, medullary rays fine dense, radiate, pith white, lax or fallen off, odour, slightly aromatic and taste weak.
Identification :
Processing : eliminate foreign matter, soak briefly, soften thoroughly and cut into thick slices and dry.
Action : To regulate the flow of qi and the function of the stomach, to alleviate pain, and to prevent abortion.
Indication : feeling of stuffiness in the chest, epigastralgia, belching and vomiting; threatened abortion
Precautions :
Dosage : 5 to 9 g.
Storage : Preserve in a cool and dry place.
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Lao Sugeng ÀÏËÕ¹£
Suye ËÕÒ¶
Zisuye ×ÏËÕÒ¶
Chinese Name (pinyin): Zisu
Chinese Name :
Common Name :Purple common Perilla
Specific Name : Folium et Caulis Perillae
Scientific Name:
Collection :
Description :
Identification :
Processing :
Action :
Indication :
Precautions :
Dosage : 6-12g for decocted/30-60g for fish or crab poisoning
Storage :
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Zisuye
Chinese Name :
Common Name :Perilla Leaf
Specific Name : Folium perillae
Scientific Name:
Collection : The drug is collected in summer when foliage branch growing luxuriantly, removed from foreign matter and dried in the sun.
Description : Mostly crumpled, rolled and broken, when whole, ovate, 4 0 11cm long, 2.5 - 9cm wide, apex long acuminate or acute, base rounded or broadly cuneate, margin crenate. Both surface purple or upper surface green and the lower purple with scattered greyish white hairs and numerous point shaped glandular scales, petioles 2 - 7mm in diameter, purplish green with a pith in the center of fructure, odor delicately aromatic, taste slightly pungent.
Identification : 1.Leaf in the surface view: Some epidermal cells containing purplish pigment, a red color is produced immediately on adding 10% hydrochloric acid nsolution, or a green color is produced on adding 5% potassium hydroxide solution, subsequently cahnged to yellowish green.2.To 0.7g of the powder in a round bottom flask add 250ml of water, mix well and connect the flask with volatile oil determination apparatus. Add water from the top of the apparatus until it reaches the mark and overflows to the flask. Add to the flask 1.5ml of petroleum ether (60 - 90ºC) and connect the flask to boil and continue heating to gentle boiling for 2 hours, cool, separate the petroleum ether layer and used it as the test solution. Prepare the solution of 0.7g Folium Perillae reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G as the coating substance and petroleum ether (60 - 90ºC)-ethyl acetate (19:1) as the mobile phase. Apply separately 10µl each of the two solutions to the plate. After developing (with 15cm developing distance) and removal of the plate, dry it in the air, spray with dinitrophenylhrdrazine TS and wait. The spots in the chromatogram obtained with the test solution correspond in position and color to the spots in the chromatogram obtained with the reference dreug solution.
Processing : Eliminate foreign matter and old branches, spray with water, cut into pieces and dry.
Action : To induce perspiration and dispel cold, and to regulate the stomach function.
Indication : common cold with cough and nausea; vomiting of pregnancy; fish or crab poisoning
Precautions :
Dosage : 4.5 to 9 g.
Storage : Preserve in a cool and dry place.
Nomenclature
Other Names:
Historical Use of Perilla frutescens
Perilla frutescens in Traditional Chinese Medicine
Background
Chaosuzi ³´ËÕ×Ó
Suzi ËÕ×Ó
Chinese Name (pinyin): Zisuzi
Chinese Name :
Common Name :Perilla Fruit
Specific Name : Fructus perillae
Scientific Name:
Collection : The drug is collected in autumn when ripe, remove from foreign matter and dried in the sun.
Description : Ovoid or subspherical, 1.5mm in diameter. Externally greyish brown with dark purple and slightly protuberant reticulate striations, base slightly acute with greyish white and pointed fruit stalk scar. Pericarp thin and fragile, easily broken, seeds yellowish white, testa membranous, cotyledons 2, whitish and oily, odor aromatic on pressing, taste slightly pungent.
Identification :
Processing : Eliminate foreign matter, wash, clean and dry.Stir fried: stir fry as described under the method of simple stir frying (Appendix ll D) until the drug burst.
Action : To relieve dyspnea and cough, to eliminate phlegm, and to relax bowels.
Indication :
Precautions :
Dosage : 3 to 9 g.
Storage : Preserve in a ventilated and dry place, protected from moth.
Synonymns for Perilla frutescens
Patent Medicines and Medicines with Multiple Ingredients that include Perilla frutescens
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Perilla frutescens in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Ling Zhu, Lijun Guan, Kunlun Wang, Chuanying Ren, Yang Gao, Jialei Li, Song Yan, Xindi Zhang, Xinmiao Yao, Ye Zhou, Bo Li, Shuwen Lu
##Title##
Front Nutr: 2024, 11;1359813
[PubMed:38585610]
[WorldCat.org]
[DOI]
(P e)
Vasudeva Reddy Netala, Tianyu Hou, Siva Sankar Sana, Huizhen Li, Zhijun Zhang
##Title##
Molecules: 2024, 29(6);
[PubMed:38542889]
[WorldCat.org]
[DOI]
(I e)
So Jung Jang, Kyu Jin Sa, Zhen Yu Fu, Ju Kyong Lee
##Title##
Heliyon: 2024, 10(5);e26720
[PubMed:38455579]
[WorldCat.org]
[DOI]
(P e)
Hyung Jong Nam, Min Jung Park, Bo Sun Joo, Yean Kyoung Koo, SukJin Kim, Sang Don Lee, Hyun Jun Park
##Title##
World J Mens Health: 2024;
[PubMed:38449453]
[WorldCat.org]
[DOI]
(P a)
Guanwen Xie, Xiuzai Zou, Zishan Liang, Ke Zhang, Duan Wu, Honglei Jin, Hongbin Wang, Qi Shen
GBF family member PfGBF3 and NAC family member PfNAC2 regulate rosmarinic acid biosynthesis under high light.
Plant Physiol: 2024;
[PubMed:38441888]
[WorldCat.org]
[DOI]
(I a)