Peony root

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Peony root is a non-scientific common name that may refer to a number of plant species and varieties.


Other Names:

Historical Use of Peony root

Peony root in Traditional Chinese Medicine


Historical Use of Peony root in Western Medicine

Quote Paraph: per De Horta writing in 1754 in Mexico, "During the fit, anodyne and sedative substances such as a distillate of the fragrant flowers of the salvia an rosemary and of the so often recommended peony root were to be given."
Sec Auth: Eadie MJ and Bladin PF
Title: A Disease Once Sacred. John Libbey & Company Ltd, 2001
Page: 191
Source: A Disease Once Sacred, John Libbey & Company Ltd, 2001, M.J. Eadie and P.F. Bladin
Complete: Eadie MJ, Bladin PF. A disease once sacred: a history of the medical understanding of epilepsy. Eastleigh: John Libbey; 2001. p. 191.
Primary Source:


Synonymns for Peony root

Patent Medicines and Medicines with Multiple Ingredients that include Peony root

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Peony root in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Dong-Hai Liu, Elvis Agbo, Shu-Hong Zhang, Jin-Ling Zhu
Anticonvulsant and Neuroprotective Effects of Paeonol in Epileptic Rats.
Neurochem. Res.: 2019, 44(11);2556-2565
[PubMed:31520267] [] [DOI] (I p)

Eiichi Sugaya, Wen Jin, Aiko Sugaya, Katsuyoshi Sunaga, Tadashi Tsuda
Inhibitory effects of peony root extract on the large conductance calcium-activated potassium current essential in production of bursting activity.
J Herb Pharmacother: 2006, 6(2);65-77
[PubMed:17182486] [] (P p)

Katsuyoshi Sunaga, Eiichi Sugaya, Kagemasa Kajiwara, Tadashi Tsuda, Aiko Sugaya, Minoru Kimura
Molecular mechanism of preventive effect of peony root extract on neuron damage.
J Herb Pharmacother: 2004, 4(1);9-20
[PubMed:15273073] [] (P p)

T Tsuda, A Sugaya, H Ohguchi, N Kishida, E Sugaya
Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model.
Exp. Neurol.: 1997, 146(2);518-25
[PubMed:9270063] [] [DOI] (P p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects