Paeonia suffruticosa

From Epilepsy Naturapedia
Jump to: navigation, search
P221 1.jpg
P221 2.jpg

Nomenclature

Other Names:

Historical Use of Paeonia suffruticosa

Paeonia suffruticosa in Traditional Chinese Medicine

Background

Danpitan µ¤Æ¤Ì¿ Fendanpi ·Ûµ¤Æ¤ Jiudanpi ¾Æµ¤Æ¤ Chinese Name (pinyin): Mudanpi

Chinese Name  :

Common Name  :Moutan Bark

Specific Name  : Cortex moutan

Scientific Name:
Collection  : The root is collected in autumn, removed from the rootlets, the root bark is stripped off and dried in the sun.

Description  : Quilled or semiquilled, longitudinally fissured, somewhat involute or opened, 5-20cm long, 5-12mm in diameter, 1-4mm thick. The outer surface greyish-brown, showing numerous transverse lenticels and rootlet scars, the exposed layer where cork fallen off appearing pink, the inner surface greyish-yellow or brownish with obvious fine longitudinal striations, usually showing bright crystals. Texture hard and fragile, easily broken, fracture relatively even, starchy, pale pink, odour aromatic, taste slightly bitter and astringent.

Identification  : 1.Powder: Pale reddish brown, starch granules fairly abundant, simple granules subrounded or polygonal, 3-6µm in diameter, hilum pointed, cleft or V-shaped, compound granules of 2-6 components. Clusters of calcium oxalate 9-45µm in diameter, sometimes crystal cells joined arranged in rows or several clusters in one cell. Cork cells rectangular, slightly thick walled, pale red.2.Shake 0.15 of the powder with 25ml of dehydrated ethanol for several minutes and filter. Dilute 1ml of the filtrate to 25ml of dehydrated ethanol. Carry out the method for spectrophotometry (Appendix V A). The light absorption exhibits a maximum at 274nm.3.Shake 1g of the powder with 10ml of ether for 10 minutes and filter. Evaporate the filtrate to dryness, to the residue add 2ml of acetone as the test solution. Dissolve paeonol CRS in acetone to produce a solution containing 5mg per ml as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G as the coating substance and cyclohexane-ethyl acetate (3:1) as the mobile phase. Apply separately to the plate 10µl of each of the two solutions. After developing and removal of the plate, dry it in the air and spray with a 5% solution of ferric chloride in ethanol acidified with hydrochloric acid. Dry the plate with a current or hot air until the spots are observe clearly. A bluish brown spot is shown in the chromatogram obtained with the test solution correspond in position and colour with the spot in the chromatogram obtained with the reference solution.Water: Carry out the determination of water (Appendix lX H, mathod 2) not more than 13.0%Total Ash: Not more than 5.0% (Appendix lX K).Assay: Distill 0.2g of the powder, accurately weighed with steam, collect about 450ml of distillate, dilute 500ml with water and shake well. Carry out the method for spectrophotomery (Appendix V A) measure the absorbance of the solution at 274nm and calculate the content of C9H10O3, taking 862 as the value of A (1%, 1cm). It contains not less than 1.20% of paeonol (C9H10O3,) calculated on the dried basis.

Processing  : Wash rapidly, soften cut into slices and dry in the sun.

Action  : To remove heat from blood, to activate blood circulation and eliminate blood stasis.

Indication  : eruptions in epidemic diseases; spitting of blood, epistaxis; consumptive fever occurring at night and subsiding in the mornin without sweating; amenorrhea, dysmenorrhea; carbuncles and sores; traumatic injuries

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a cool and dry place.

Synonymns for Paeonia suffruticosa

Patent Medicines and Medicines with Multiple Ingredients that include Paeonia suffruticosa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Paeonia suffruticosa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Jie Gao, Jingqi Xue, Yuqian Xue, Rong Liu, Xiuxia Ren, Shunli Wang, Xiuxin Zhang
Transcriptome sequencing and identification of key callus browning-related genes from petiole callus of tree peony (Paeonia suffruticosa cv. Kao) cultured on media with three browning inhibitors.
Plant Physiol. Biochem.: 2020, 149;36-49
[PubMed:32035251] [WorldCat.org] [DOI] (I a)

Gaoming Lei, Chaoying Song, Yongqiang Luo
##Title##
Nat. Prod. Res.: 2020;1-5
[PubMed:31928365] [WorldCat.org] [DOI] (I a)

Chao Zhang, Lili Zhang, Jianxin Fu, Li Dong
Isolation and characterization of hexokinase genes PsHXK1 and PsHXK2 from tree peony (Paeonia suffruticosa Andrews).
Mol. Biol. Rep.: 2020, 47(1);327-336
[PubMed:31677036] [WorldCat.org] [DOI] (I p)

Aleksandra Shedoeva, David Leavesley, Zee Upton, Chen Fan
Wound Healing and the Use of Medicinal Plants.
Evid Based Complement Alternat Med: 2019, 2019;2684108
[PubMed:31662773] [WorldCat.org] [DOI] (P e)

Jilei Wang, Guiying Wu, Haiping Chu, Zhongyu Wu, Jingyong Sun
Paeonol Derivatives and Pharmacological Activities: A Review of Recent Progress.
Mini Rev Med Chem: 2019;
[PubMed:31644406] [WorldCat.org] [DOI] (I a)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects