Opiates

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Opiates is a non-scientific common name that may refer to a number of plant species and varieties.

Nomenclature

Other Names:

Historical Use of Opiates

Opiates in Traditional Chinese Medicine

Description

Historical Use of Opiates in Western Medicine

Quote Paraph: Under the subject "Of Wounds in General" and the subtopic "Of Convulsions", Boerhaave writes "234. The Cure is perform'd, 1. By removing whatever doth irritate, by the skilful hand of a Surgeon (187, 188.) 2. By softning [WORD IS DIFFICULT TO READ; may say foftning, fostning, or sostning] the sharp Acrimony, or dissipating it. 2. By changing the condition of the Nerves with means describ'd in (228, 229.) [...] 229. The Sense of Pain may be removed, though its Cause subsists, 1. By making the Nerve incapable of feeling, by a pressure, cutting, or burning of the fame. 2. By blunting the very head and fountain of all Feeling with Opiates : Which also remove several Effects proceeding from the Sense of Pain, (226.)"
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Primary Source: Boerhaave. Boerhaave's aphorisms concerning the knowledge and cure of diseases. Translated by Delacoste J. London. Cowse and Innys in St. Paul's Church-Yard. 1715. p. 56.

Background

Synonymns for Opiates

Patent Medicines and Medicines with Multiple Ingredients that include Opiates

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Opiates in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Yu-Chi Wang, Sanjeet S Grewal, Anshit Goyal, Mohammed Ali Alvi, Gregory Worrell, Benjamin Brinkmann, Lily Wong-Kisiel, Jeffrey Britton, W Richard Marsh, David Burkholder, Eric Payne, Cheolsu Shin, Gregory Cascino, Brian N Lundstrom, Min-Hsien Wu, Jamie J Van Gompel
Comparison of narcotic pain control between stereotactic electrocorticography and subdural grid implantation.
Epilepsy Behav: 2020, 103(Pt A);106843
[PubMed:31882325] [WorldCat.org] [DOI] (I p)

A B Olorukooba, S Odoma
Elucidation of the possible mechanism of analgesic action of methanol stem bark extract of Uapaca togoensis pax in mice.
J Ethnopharmacol: 2019, 245;112156
[PubMed:31415847] [WorldCat.org] [DOI] (I p)

Hongmei Dai, Peipei Wang, Huafang Mao, Xiao Mao, Shan Tan, Zhiheng Chen
Dynorphin activation of kappa opioid receptor protects against epilepsy and seizure-induced brain injury via PI3K/Akt/Nrf2/HO-1 pathway.
Cell Cycle: 2019, 18(2);226-237
[PubMed:30595095] [WorldCat.org] [DOI] (I p)

María Rodríguez-Muñoz, Yara Onetti, Elsa Cortés-Montero, Javier Garzón, Pilar Sánchez-Blázquez
Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor.
Mol Brain: 2018, 11(1);51
[PubMed:30223868] [WorldCat.org] [DOI] (I e)

Armin Shirzadian, Sattar Ostadhadi, Mahsa Hassanipour, Hamed Shafaroodi, Mina Khoshnoodi, Arya Haj-Mirzaian, Mohammad Sharifzadeh, Shayan Amiri, Mehdi Ghasemi, Ahmad Reza Dehpour
Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and cannabinoids.
Epilepsy Behav: 2018, 87;25-31
[PubMed:30170259] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects