Ophiopogon japonicus

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Tcm407.jpg
P196 2.jpg

Nomenclature

Other Names:

Historical Use of Ophiopogon japonicus

Ophiopogon japonicus in Traditional Chinese Medicine

Background

Cundong ´ç¶¬ Maidong Âó¶¬ Chinese Name (pinyin): Maimendong

Chinese Name  :

Common Name  :Ophiopogon Root

Specific Name  : Radix Ophiopogonis

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-12g

Storage  :

Tcm407.jpg
P196 2.jpg

Nomenclature

Other Names:

Historical Use of Ophiopogon japonicus

Ophiopogon japonicus in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Maidong

Chinese Name  :

Common Name  :Dwarf Lilyturf Tuber

Specific Name  : Radix ophiopogonis

Scientific Name:
Collection  : The drug is collected in summer, washed clean, sun-dried and piled up repeatedly until nearly dry. Removed from rootlet and dried.

Description  : Fusiform with two ends slightly tapering, 1.5 - 3 cm long, 3 - 6 mm in diameter, externally yellowish white, finely wrinkled longitudinally. Texture tough, fracture yellowish white, translucent, stele small, odour slightly aromatic, taste sweetish and bitterish.

Identification  : Transverse section: Epidermis consisting of 1 layer of cells. Velamen of 3 - 5 layers of lignified cells. Cortex broad, scattered with mucilage cells containing raphides oc calcium oxalate, some needles up to 10 µm in diameter. Endodermis cells with evenly thickened and lignified walls and with passage cells, a layer of stone cells lying at the outside of endodermis, the inner and lateral walls thickened, finely and dosely pitted, Stele relatively small. Phloem bundles 16 - 22, each located between the xylem arms respectively. Vessels tracheids, fibres and lignified parenchymatous cells in the inner side of the xylem bundles linking up to a ring. Pith small, parenchymatous cells subrounded.1.Examine a thin slice of the drug under ultra violet light (365 nm), a pale blue fluorescence is produced.Water: Carry out the method for determination of water (Appendix lX H, method 1) not more than 18.0%Extractives: Carry out the cold extraction for water soluble extractive (Appendix X A) not less than 60.0%.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, press to be flattened and dry.

Action  : To mourish yin and promote the production of body fluid, to moisten the lung, and to ease the mind.

Indication  : dry cough, phthisical cough; thirst due to impairment of body fluid; fidgetness and insomnia; diabetes caused by internal heat; constipation; diphtheria

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a cool and dry place, protected from moisture.

Tcm407.jpg
P196 2.jpg

Nomenclature

Other Names:

Historical Use of Ophiopogon japonicus

Ophiopogon japonicus in Traditional Chinese Medicine

Background

Cundong ´ç¶¬ Maidong Âó¶¬ Chinese Name (pinyin): Maimendong

Chinese Name  :

Common Name  :Ophiopogon Root

Specific Name  : Radix Ophiopogonis

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  :

Indication  :

Precautions  :

Dosage  : 6-12g

Storage  :

Tcm407.jpg
P196 2.jpg

Nomenclature

Other Names:

Historical Use of Ophiopogon japonicus

Ophiopogon japonicus in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Maidong

Chinese Name  :

Common Name  :Dwarf Lilyturf Tuber

Specific Name  : Radix ophiopogonis

Scientific Name:
Collection  : The drug is collected in summer, washed clean, sun-dried and piled up repeatedly until nearly dry. Removed from rootlet and dried.

Description  : Fusiform with two ends slightly tapering, 1.5 - 3 cm long, 3 - 6 mm in diameter, externally yellowish white, finely wrinkled longitudinally. Texture tough, fracture yellowish white, translucent, stele small, odour slightly aromatic, taste sweetish and bitterish.

Identification  : Transverse section: Epidermis consisting of 1 layer of cells. Velamen of 3 - 5 layers of lignified cells. Cortex broad, scattered with mucilage cells containing raphides oc calcium oxalate, some needles up to 10 µm in diameter. Endodermis cells with evenly thickened and lignified walls and with passage cells, a layer of stone cells lying at the outside of endodermis, the inner and lateral walls thickened, finely and dosely pitted, Stele relatively small. Phloem bundles 16 - 22, each located between the xylem arms respectively. Vessels tracheids, fibres and lignified parenchymatous cells in the inner side of the xylem bundles linking up to a ring. Pith small, parenchymatous cells subrounded.1.Examine a thin slice of the drug under ultra violet light (365 nm), a pale blue fluorescence is produced.Water: Carry out the method for determination of water (Appendix lX H, method 1) not more than 18.0%Extractives: Carry out the cold extraction for water soluble extractive (Appendix X A) not less than 60.0%.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, press to be flattened and dry.

Action  : To mourish yin and promote the production of body fluid, to moisten the lung, and to ease the mind.

Indication  : dry cough, phthisical cough; thirst due to impairment of body fluid; fidgetness and insomnia; diabetes caused by internal heat; constipation; diphtheria

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a cool and dry place, protected from moisture.

Synonymns for Ophiopogon japonicus

Patent Medicines and Medicines with Multiple Ingredients that include Ophiopogon japonicus

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Ophiopogon japonicus in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Yuanyuan Zhang, Yazheng Zhao, Yan Wu, Jin Qi, Fang Li, Junping Kou, Boyang Yu
Ophiopogon Saponin C1 Inhibits Lung Tumors by Stabilizing Endothelium Permeability via Inhibition of PKCδ.
Int. J. Biol. Sci.: 2020, 16(3);396-407
[PubMed:32015677] [WorldCat.org] [DOI] (I e)

Xu Deng, Jinju Xu, Chaoying Tong, Fangying Shi, Shuyun Shi
Homoisoflavonoids profiling of Ophiopogon japonicus by off-line coupling high-speed counter-current chromatography with high performance liquid chromatography-diode array detector-quadrupole time-of-flight tandem mass spectrometry.
J Sep Sci: 2020;
[PubMed:31999027] [WorldCat.org] [DOI] (I a)

Qi-Wei Yao, Xiao-Ying Wang, Jian-Cheng Li, Jun Zhang
Ophiopogon japonicus inhibits radiation-induced pulmonary inflammation in mice.
Ann Transl Med: 2019, 7(22);622
[PubMed:31930023] [WorldCat.org] [DOI] (P p)

Sairong Fan, Junfeng Zhang, Qi Xiao, Peng Liu, Yining Zhang, Enze Yao, Xiaoming Chen
Cardioprotective effect of the polysaccharide from Ophiopogon japonicus on isoproterenol-induced myocardial ischemia in rats.
Int. J. Biol. Macromol.: 2020, 147;233-240
[PubMed:31923517] [WorldCat.org] [DOI] (I a)

Zhiwang Song, Xiaojun Xiang, Junhe Li, Jun Deng, Ziling Fang, Ling Zhang, Jianping Xiong
Ruscogenin induces ferroptosis in pancreatic cancer cells.
Oncol. Rep.: 2020, 43(2);516-524
[PubMed:31894321] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects