Notopterygium incisum

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Nomenclature

Other Names:

Historical Use of Notopterygium incisum

Notopterygium incisum in Traditional Chinese Medicine

Background

Chuanqianghuo ´¨Ç¼»î Xiqianghuo Î÷Ǽ»î Chinese Name (pinyin): Qianghuo

Chinese Name  :

Common Name  :Notopterygium Root

Specific Name  : Rhizoma seu radix notopterygii

Scientific Name:
Collection  : The drug is collected in spring and winter, removed from rootlet and soil, dried in the sun.

Description  : Rhizome of Notopterygium incisum: Cylindrical and somewhat curved. 4 - 13 cm long, 0.6 - 2.5 cm in diameter. Apex with stem scars. Externally brown to blackish brown or yellow where the outer bark fallen off. Internodes shortened, forming dense raised annulations like silk worm (known as Canqiang); or internodes elongated like the nodes of a bamboo (known as Zhujiaqiang). Nodes exhibiting numerous dotted or tuberculate root scar and brown broken scales. Texture light and fragile, easily broken. Fracture uneven with clefts, bark yellowish brown to dark brown, oily with numerous brown oil dots. Wood yellowish white with distinct rays, pith yellow to yelolowish brown. Odor aromatic, taste: slightly bitter and pungent.Rhizome and root of Notopterrygium forbesii: Rhizomes subcylindrical, bearing stems and remains of leaf sheaths, root sub-conical, longitudinally wrinkled and lenticellate, externally brown, with dense annulations near rhizome. 8 - 15 cm long, 1 - 3 cm in diameter (known as Tiaoqiang). Some rhizomes large and stout, irregularly nodiform. Apex bearing several stem bases, roots relatively thin (known as Datouqiang). Texture loose and fragile and easily broken. Fracture slightly even, bark pale brown, wood yellowish white. Odor ant taste relatively slight.

Identification  :

Processing  : Eliminate foreign matters, wash clean, soften thoroughly, cut into thick slices and dry it in the sun.

Action  : To relieve pain and rheumatic conditions.

Indication  : headache in common cold, rheumatic arthralgia and aching of the back and shoulders

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a cool and dry place, protected from moth.

Synonymns for Notopterygium incisum

Patent Medicines and Medicines with Multiple Ingredients that include Notopterygium incisum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Notopterygium incisum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Ko-Ta Chen, Chi-Tai Yeh, Vijesh Kumar Yadav, Narpati Wesa Pikatan, Iat-Hang Fong, Wei-Hwa Lee, Yen-Shuo Chiu
Notopterol mitigates IL-1β-triggered pyroptosis by blocking NLRP3 inflammasome via the JAK2/NF-kB/hsa-miR-4282 route in osteoarthritis.
Heliyon: 2024, 10(6);e28094
[PubMed:38532994] [WorldCat.org] [DOI] (P e)

Qian-Qian Gan, Ping Yang, Hong-Lan Wang, Wen-Tao Zhu, Jing-Cheng Wang, Teng Liu, Jiu-Zhen DU, Shun-Yuan Jiang
[Morphological and biochemical characterization during seed development of Notopterygium incisum].
Zhongguo Zhong Yao Za Zhi: 2024, 49(2);354-360
[PubMed:38403311] [WorldCat.org] [DOI] (P p)

Jianpeng Zhou, Peilei Shi, Rui Ma, Xudong Xie, Lei Zhao, Jun Wang
Notopterol Inhibits the NF-κB Pathway and Activates the PI3K/Akt/Nrf2 Pathway in Periodontal Tissue.
J Immunol: 2023, 211(10);1516-1525
[PubMed:37819772] [WorldCat.org] [DOI] (I p)

Peijun Liu, Weihua Tang, Dong Zhao, Pan Zhou, Ke Hu
##Title##
Front Pharmacol: 2023, 14;1185100
[PubMed:37719850] [WorldCat.org] [DOI] (P e)

Yuhan Qu, Lu Qiu, Hui Qiu, Yue Shen, Min Tang, Yuehui Huang, Yi Peng, Jun Wang, Qiang Fu
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Cytokine: 2023, 169;156309
[PubMed:37517294] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects