Momordica cochinchinensis

Background

Chinese Name (pinyin): Mubiezi

Chinese Name  :

Common Name  :Cochinchina Momordica Seed

Specific Name  : Semen momordicae

Scientific Name:
Collection  : The ripe fruit is collected in winter, cut and a half dried in the sun. The removed from the pulp and dried.

Description  : Flattened plate like, slightly raised or dented in the center,2 - 4cm in diameter about thick. Externally greyish brown to blackish brown with reticulated pattern and a yellowish hilum at the relatively larger dentate protruding the in the margin. Tetsta hard and brittle, endotesta greyish green, tomentous like. 2 cotyledons, yellowish white, oily. Odor characteristically greasy and taste bitter.

Identification  : 1. Powder: Yellowish-grey. Sclerenchymatous cells elliptical or sub-rounded, sinuous-margined, 51-117µm in diameter, with thickened and lignified walls, and lumina distinct and some narrowed. Parenchymatous cells of cotyledons polygonal, containing fixed oil masses and aleurone grains; fixed oil masses sub-rounded, 27-73µm in diameter, reticulated striations visible on the surface.2. To 2g of the coarse powder add 20ml of ether macerate warmly for 30 minutes and filter. Place 2ml of the ether extract into a glass dish, evaporate to dryness. To the residue add a small quantity of anhydrous sodium sulfate, heat, bubbles and thick white irritating gas are produced. 3. To 2g of the coarse powder add 20ml of water, heat on a water bath for 30 minutes, filter. Place 2ml of the filtrate into a stoppered test tube, shake vigorously for 1 minute, a large amount of foam is produced, which persists for 10 minutes.

Processing  : Semen Momordicae: Remove the shell and break the kernel to pieces.

Action  : To promote the subsidence of nodulation and swelling, combat poisons and cure sores.

Indication  : sores and inflammatory swelling, mastitis, scrofula, hemorrhoids, anal fistula, chronic eczema, neurodermatitis,scald

Precautions  :

Dosage  : 0.9 to 1.2 g for oral administration; appropriate quantity to be ground into powder and mixed with oil or vinegar for topical application.

Storage  : Preserve in a dry place.

Evidence or the Use of Momordica cochinchinensis in the Treatment of Epilepesy

1st Five Results: pubmed search

Kanathip Singsai, Niwat Saksit, Puwich Chaikhumwang
Brain acetylcholinesterase activity and the protective effect of Gac fruit on scopolamine-induced memory impairment in adult zebrafish.
IBRO Neurosci Rep: 2024, 16;368-372
[PubMed:38435743] [WorldCat.org] [DOI] (I e)

Márton Ivánczi, Balázs Balogh, Loretta Kis, István Mándity
Molecular Dynamics Simulations of Drug-Conjugated Cell-Penetrating Peptides.
Pharmaceuticals (Basel): 2023, 16(9);
[PubMed:37765059] [WorldCat.org] [DOI] (P e)

Worrapan Poomanee, Nara Yaowiwat, Tunpidcha Pattarachaidaecharuch, Pimporn Leelapornpisid
Optimized multiherbal combination and in vivo anti-skin aging potential: a randomized double blind placebo controlled study.
Sci Rep: 2023, 13(1);5633
[PubMed:37024608] [WorldCat.org] [DOI] (I e)

Lijuan Cai, Rao Pan, Qun Zeng, Xiaoyan Zhang, Rongbin Zeng, Qianglong Zhu
##Title##
Mitochondrial DNA B Resour: 2023, 8(3);329-332
[PubMed:36876141] [WorldCat.org] [DOI] (I e)

Dao Nguyen, Jessica Holien, Chaitali Dekiwadia, Thilini Thrimawithana, Terrence Piva, Tien Huynh
##Title##
Pharmaceuticals (Basel): 2023, 16(1);
[PubMed:36678596] [WorldCat.org] [DOI] (P e)