Lygodium japonicum

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Other Names:

Historical Use of Lygodium japonicum

Lygodium japonicum in Traditional Chinese Medicine


Chinese Name (pinyin): Haijinsha

Chinese Name  :

Common Name  :Climbing Fern Spore

Specific Name  : Spora lygodii

Scientific Name:
Collection  : The plant is collected in autumn when the spore has not fallen off and dried in the sun. The spore is tapped out, remove from the stem and leaf.

Description  : Powder like, brownish yellow or pale brownish yellow. Texture light and smooth with lubricant feeling when twisted with the finger. Odor slight and taste weak.

Identification  : 1.Scatter small quantity of spores on fire, a slightly bursting noise and a bright flame are produced.2.Powder: brownish yellow, spore tetrahedral or triangular conical, tri-phase conical in top view. Y-shaped fissures visible, sub-triangular in lateral view, sub-rounded in bottom view, 60 - 85µm in diameter with glandular sculptures in outer walls.Acid insoluble ash: Not more than 15% (Appendix 1X K)

Processing  :

Action  : To remove damp-heat and relieve dysuria.

Indication  : acute urinary tract infection. urolithiasis, hematuria, chyluria, urethral pain with difficult urination

Precautions  :

Dosage  : 6 to 15 g.

Storage  : Preserve in a dry place.

Synonymns for Lygodium japonicum

Patent Medicines and Medicines with Multiple Ingredients that include Lygodium japonicum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Lygodium japonicum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Young-Chang Cho, Ba Reum Kim, Hien Thi Thu Le, Sayeon Cho
Anti‑inflammatory effects on murine macrophages of ethanol extracts of Lygodium japonicum spores via inhibition of NF‑κB and p38.
Mol Med Rep: 2017, 16(4);4362-4370
[PubMed:29067444] [] [DOI] (I p)

Florencia Berruezo, Flávio S J de Souza, Pablo I Picca, Sergio I Nemirovsky, Leandro Martínez Tosar, Mercedes Rivero, Alejandro N Mentaberry, Alicia M Zelada
Sequencing of small RNAs of the fern Pleopeltis minima (Polypodiaceae) offers insight into the evolution of the microrna repertoire in land plants.
PLoS ONE: 2017, 12(5);e0177573
[PubMed:28494025] [] [DOI] (I e)

Naoko Takahashi, Chieko Kami, Isao Ota, Nana Morita, Ryoko Imaichi
Developmental morphology of the typical cordate gametophyte of a homosporous leptosporangiate fern, Lygodium japonicum (Lygodiaceae), focusing on the initial cell behavior of two distinct meristems.
Am. J. Bot.: 2015, 102(2);197-207
[PubMed:25667072] [] [DOI] (I p)

Koichiro Aya, Masaaki Kobayashi, Junmu Tanaka, Hajime Ohyanagi, Takayuki Suzuki, Kenji Yano, Tomoyuki Takano, Kentaro Yano, Makoto Matsuoka
De novo transcriptome assembly of a fern, Lygodium japonicum, and a web resource database, Ljtrans DB.
Plant Cell Physiol.: 2015, 56(1);e5
[PubMed:25480117] [] [DOI] (I p)

Hyuk Jin Cho, Woong Jin Bae, Su Jin Kim, Sung Hoo Hong, Ji Youl Lee, Tae-Kon Hwang, Yeong Jin Choi, Sung Yeoun Hwang, Sae Woong Kim
The inhibitory effect of an ethanol extract of the spores of Lygodium japonicum on ethylene glycol-induced kidney calculi in rats.
Urolithiasis: 2014, 42(4);309-15
[PubMed:24972555] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects