Lycopus lucidus

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Other Names:

Historical Use of Lycopus lucidus

Lycopus lucidus in Traditional Chinese Medicine


Zelanye ÔóÀ¼Ò¶ Chinese Name (pinyin): Zelan

Chinese Name  :

Common Name  :Bugleweed

Specific Name  : Herba lycopi

Scientific Name:
Collection  : The drug is collected in between summer and autumn when the stems and the leaves are growing luxuriantly and dried in the sun.

Description  : tems square, infrequently branched, shallowly furrowed longitudinally on four sides, 50 - 100cm long, 2 - 6mm in diameter, externally yellowish green or purplish, nodes apparently purple, white tomentose, texture fragile, fracture yellowish white, pith hollowed. Leaves opposite, short petiole, lamina mostly crumpled when whole, lanceolate or oblong, 5 - 10cm long. The upper surface greyish green and densely glandular-dotted, pubescent on both surfaces, apex acute, margins serrate. Flowers yellowish brown, aggregated leaf axils in venticillate cymes, corolla mostly fallen off, bracts and calyx persistent, odorless and taste weak.

Identification  :

Processing  : Eliminate foreign matter, wash briefly, soften thoroughly, cut into sections and dry.

Action  : To activate blood circulation and eliminate blood stasis, and to induce diuresis.

Indication  : menstrual disorders, amenorrhea, dysmenorrhea, postpartum abdominal pain due to blood stasis; edema

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a ventilated dry place.

Synonymns for Lycopus lucidus

Patent Medicines and Medicines with Multiple Ingredients that include Lycopus lucidus

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Lycopus lucidus in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Shengfang Xie, Fengfeng Ge, Yuanzhang Yao, Wei Zhang, Shuopeng Wang, Min Zhang, Rongling Zhong, Liming Fang, Ding Qu
The aqueous extract of Lycopus lucidus Turcz exerts protective effects on podocytes injury of diabetic nephropathy via inhibiting TGF-β1 signal pathway.
Am J Transl Res: 2019, 11(9);5689-5702
[PubMed:31632540] [] (P e)

Jinlu Liu, Sai Bhuvanagiri, Xiaohan Qu
The protective effects of lycopus lucidus turcz in diabetic retinopathy and its possible mechanisms.
Artif Cells Nanomed Biotechnol: 2019, 47(1);2900-2908
[PubMed:31307239] [] [DOI] (I p)

Da-Won Jeong, Eun-Young Kim, Jae-Hyun Kim, Bina Lee, SooYeon Hong, Jae Ho Park, Hyuk-Sang Jung, Youngjoo Sohn
Evid Based Complement Alternat Med: 2019, 2019;3231784
[PubMed:30915145] [] [DOI] (P e)

Mi Ra Lee, Hye Jin Yang, Kwang Il Park, Jin Yeul Ma
Lycopus lucidus Turcz. ex Benth. Attenuates free fatty acid-induced steatosis in HepG2 cells and non-alcoholic fatty liver disease in high-fat diet-induced obese mice.
Phytomedicine: 2019, 55;14-22
[PubMed:30668424] [] [DOI] (I p)

Kwang-Youn Kim, Tae Woo Oh, Jin-Yeul Ma, Kwang-Il Park
Evid Based Complement Alternat Med: 2018, 2018;9513290
[PubMed:30105080] [] [DOI] (P e)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects