Lycopodium japonicum

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Nomenclature

Other Names:

Historical Use of Lycopodium japonicum

Lycopodium japonicum in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Shenjincao

Chinese Name  :

Common Name  :Club Moss

Specific Name  : Herba lycoopodii

Scientific Name:
Collection  : The drug is collected in summer and autumn when foliage branch growing luxuriantly, removed from foreign matter and dried in the sun.

Description  : Stolons thin-cylindrical, slightly curved up to 2m long, 1 - 3mm in diameter with yellowish white rootlets underneath. Erect stems bifurcated. Leaves densely growing on the stems, spirally arranged crumpled and curved, linear or needle shape, 3 - 5mm long, yellowish green to pale yellowish brown, glabrous, aristate at the apex, margin entire, easily broken. Texture soft, fracture pale yellow in the bark and whitish in wood, odorless and taste weak.

Identification  : 1.Transverse section of the stem: Epidermal cells 1 row, cortex broad, scattered with leaf trace bundles, bearing 10 - 20 or more rows of sclerenchymatous cells below the epidermis and outside the stele respectively and 3 - 5 rows of parenchymatous cells with slightly thickened walls between them, endodermis indistinct. Pericycle consisting of several rows of parenchymatous cells, plectostele, bundles of xtlem irregularly strip shaped or branch intermingled with bundles of phloem, some cells containing yellowish brown masses.2.To 3g of the powder add 30ml of ethanol, heat under reflux for 20 minutes and filter. Evaporate the filtrate to dryness, add 10ml of 1% hydrochloric acid solution to the residue, stir and filter. Adjust the filtrate to pH8 with ammonia TS, extract with 10ml of chloroform, evaporate the chloroform extract to dryness and dissolve the residue in 5 ml of 1% hydrochloric acid solution. Transfer 1ml of each of the above solution to 2 test tube, add 2 drops of potassium iodobismuthate iodide TS to one tube, an orange red precipitate is produced. Add 2 drops of silicotungstic acid TS to the other, a white precipitate is produced.

Processing  : Eliminate foreign matter, wash clean, cut into sections and dry.

Action  : To relieve rheumatic conditions and muscular contracture.

Indication  : arthralgia with limited mobility of the joints

Precautions  :

Dosage  : 3 to 12 g.

Storage  : Preserve in a dry place.

Synonymns for Lycopodium japonicum

Patent Medicines and Medicines with Multiple Ingredients that include Lycopodium japonicum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Lycopodium japonicum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Xin Li, Mingqin Kang, Ningning Ma, Tan Pang, Yanjun Zhang, Hua Jin, Zhen Yang, Lili Song
##Title##
Evid Based Complement Alternat Med: 2019, 2019;5165029
[PubMed:31354854] [WorldCat.org] [DOI] (P e)

Yu Zhu, Liao-Bin Dong, Zhi-Jun Zhang, Min Fan, Qin-Feng Zhu, Yan-Yan Qi, Yu-Chen Liu, Li-Yan Peng, Xing-De Wu, Qin-Shi Zhao
Three new Lycopodium alkaloids from Lycopodium japonicum.
J Asian Nat Prod Res: 2019, 21(1);17-24
[PubMed:29373928] [WorldCat.org] [DOI] (I p)

Zhang-Hua Sun, Wei Li, Gui-Hua Tang, Sheng Yin
A new serratene triterpenoid from Lycopodium japonicum.
J Asian Nat Prod Res: 2017, 19(3);299-303
[PubMed:27416018] [WorldCat.org] [DOI] (I p)

Yong-Qiang Tian, Guang-Wan Hu, Ming-Quan Guo
Components and Anti-HepG2 Activity Comparison of Lycopodium Alkaloids from Four Geographic Origins.
Evid Based Complement Alternat Med: 2016, 2016;4631843
[PubMed:27022402] [WorldCat.org] [DOI] (P p)

Qian Yang, Yuquan Zhu, Wei Peng, Rui Zhan, Yegao Chen
A New Lycopodine-type Alkaloid from Lycopodium japonicum.
Nat. Prod. Res.: 2016, 30(19);2220-4
[PubMed:26912449] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects