Lindera aggregata

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Tcm p52 0044.jpg

Nomenclature

Other Names:

Historical Use of Lindera aggregata

Lindera aggregata in Traditional Chinese Medicine

Background

Taiwuyao ̨ÎÚÒ© Chinese Name (pinyin): Wuyao

Chinese Name  :

Common Name  :Lindera Root

Specific Name  : Radix linderae

Scientific Name:
Collection  : The drug is collecte the whole year round, removed from rootlet, washed clean either slice while fresh and dried in the sun or sun-dried directly.

Description  : Mostly spindle shape, slightly curved, some constricted in the middle to be monoliform. 6 - 15 cm long, 1 - 3 cm in diameter, externally yellowish brown with longitudinal wrinkles and sparse rootlet scars. Texture hard, slices up to 0.2 - 2 mm thick, transversely cut, surface yellow white or yellowish brown, rays radiating annual rings visible, deep in colour in the middle part. Odour aromatic, taste bitterish and pungent with a cooling sensation. Old and not spindle shape top roots can not be use medicinally.

Identification  : Powder: Yellowish white, starch granules fairly abundant, simple granules subspherical oblong or ovoid, 4 - 39 µm in diameter, hilum Y- shaped V- shaped or cleft. Compound granules consisting of 2 - 4 components. Wood fibres yellowish, mostly in bundles, 20 - 30 µm in diameter, walls about 5 µm in thickness with simple pits, lumina filled with granules. Phloem fibres nearly colorless, long spindle shaped, mostly single and scattered, 15 - 17 µm in diameter, walls very thick with indistinct pit canals. Bordered pitted vessels up to about 68 µm in diameter with closely arranged bordered pits. Cell walls of xylem rays slightly thickened, densely pitted. Oil cells oblong, containing brown secretion.

Processing  : Eliminate foreign matter, for the drug not sliced remove rootlets, grade according to size, soften thoroughly and cut into thin slices and dry.

Action  : To smooth the flow of qi and relieve pain, and to warm and tonify the kidney and the urinary bladder.

Indication  : distending pain in the chest and abdomen accompanied by dyspnea; enuresis and frequency of urination due to hypofunction of the urinary bladder; hernia; dysmenorrhea

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a cool and dry place, protected from moth.

Synonymns for Lindera aggregata

Patent Medicines and Medicines with Multiple Ingredients that include Lindera aggregata

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Lindera aggregata in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Jun-Jie Yang, Yi Chen, Mei-Li Guo, Gui-Xin Chou
Chemical constituents from the roots of Lindera aggregata and their biological activities.
J Nat Med: 2020, 74(2);441-447
[PubMed:31912311] [WorldCat.org] [DOI] (I p)

Janet Schloss, Kimberley Ryan, Rebecca Reid, Amie Steel
A randomised, double-blind, placebo-controlled clinical trial assessing the efficacy of bedtime buddy® for the treatment of nocturnal enuresis in children.
BMC Pediatr: 2019, 19(1);421
[PubMed:31706286] [WorldCat.org] [DOI] (I e)

Jun-Wei Ye, De-Zhu Li
##Title##
Appl Plant Sci: 2019, 7(8);e01213
[PubMed:31467802] [WorldCat.org] [DOI] (P e)

Xin Liu, Ji Yang, Jing Fu, Xiao-Jun Yao, Jing-Rong Wang, Liang Liu, Zhi-Hong Jiang, Guo-Yuan Zhu
##Title##
Org. Lett.: 2019, 21(14);5753-5756
[PubMed:31274330] [WorldCat.org] [DOI] (I p)

Xin Liu, Ji Yang, Xiao-Jun Yao, Xing Yang, Jing Fu, Li-Ping Bai, Liang Liu, Zhi-Hong Jiang, Guo-Yuan Zhu
Linderalides A-D, Disesquiterpenoid-Geranylbenzofuranone Conjugates from Lindera aggregata.
J. Org. Chem.: 2019, 84(12);8242-8247
[PubMed:31135158] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects