Ligusticum sinense

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Nomenclature

Other Names:

Historical Use of Ligusticum sinense

Ligusticum sinense in Traditional Chinese Medicine

Background

Chuangaoben ´¨Ë›±¾ Chinese Name (pinyin): Gaoben

Chinese Name  :

Common Name  :Ligusticum Root

Specific Name  : Rhizoma ligustici

Scientific Name:
Collection  : The drug is collected in autumn after the withering of the stem and leaf, or in next spring when seedling is emerging, remove from soil and dried.

Description  : Irregularly tubercular, cylindrical or somewhat twisted, branched, 3 - 10 cm long, 1 - 2 cm in diameter. Externally brown or dark brown, rough with longitudinal wrinkles. The upper part remaining some sunken and rounded stem bases. The lower part bearing numerous dotted, prominent root scars and radial roots. Texture light relatively hard, easily broken. Fracture yellow or yellowish white fibrous. Odour, strongly aromatic. Taste pungent bitter and slightly numbling.

Identification  :

Processing  : Eliminate foreign matter, wash soften thoroughly, cut into thick slices and dry in the sun.

Action  : To relieve pain by dispelling wind, cold and damp.

Indication  : pain at the top of the head in colds; rheumatic arthralgia

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a cool and dry place, protected from moisture and moth.

Synonymns for Ligusticum sinense

Patent Medicines and Medicines with Multiple Ingredients that include Ligusticum sinense

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Ligusticum sinense in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Amin Asadollahi, Mehdi Khoobdel, Alireza Zahraei-Ramazani, Sahar Azarmi, Sayed Hussain Mosawi
Effectiveness of plant-based repellents against different Anopheles species: a systematic review.
Malar. J.: 2019, 18(1);436
[PubMed:31864359] [WorldCat.org] [DOI] (I e)

Xiaoyi Zhang, Jiushi Liu, Shiman Gao, Rongchang Chen, Yaodong Qi, Bengang Zhang, Xiaobo Sun, Haitao Liu, Peigen Xiao
Ultra-performance convergence chromatography, a more efficient method for chemical quality evaluation of Gaoben medicinal materials compared with the ultra-performance liquid chromatography.
J Chromatogr A: 2020, 1616;460755
[PubMed:31812274] [WorldCat.org] [DOI] (I p)

Qian Wei, Jianbo Yang, Li Li, Yalun Su, Aiguo Wang
Novel phthalide dimers from the aerial parts of Ligusticum sinense Oliv cv. Chaxiong.
Fitoterapia: 2019, 137;104174
[PubMed:31100437] [WorldCat.org] [DOI] (I p)

Zhen-Wen Liu, Yu-Zhen Gao, Jing Zhou
##Title##
Front Plant Sci: 2019, 10;429
[PubMed:31024595] [WorldCat.org] [DOI] (P e)

Min-Chi Cheng, Tzong-Huei Lee, Yi-Tzu Chu, Li-Ling Syu, Su-Jung Hsu, Chia-Hsiung Cheng, Jender Wu, Ching-Kuo Lee
Melanogenesis Inhibitors from the Rhizoma of Ligusticum Sinense in B16-F10 Melanoma Cells In Vitro and Zebrafish In Vivo.
Int J Mol Sci: 2018, 19(12);
[PubMed:30545008] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects